[1]眭岩,魏孔熙,张强.中药复方液外洗联合硫磺软膏外涂治疗马拉色菌毛囊炎临床观察[J].西部中医药,2024,37(08):134-136.[doi:10.12174/j.issn.2096-9600.2024.08.30]
　SUI Yan,WEI Kongxi,ZHANG Qiang.Clinical Observation on Treating Malassezia Folliculitis by Herbal Compound Liquid for External Cleaning and Sulphur Ointment for External Application[J].Western Journal of Traditional Chinese Medicine,2024,37(08):134-136.[doi:10.12174/j.issn.2096-9600.2024.08.30]
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中药复方液外洗联合硫磺软膏外涂治疗马拉色菌毛囊炎临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年08期
页码:
134-136
栏目:
衷中参西
出版日期:
2024-08-15

文章信息/Info

Title:
Clinical Observation on Treating Malassezia Folliculitis by Herbal Compound Liquid for External Cleaning and Sulphur Ointment for External Application
作者:
眭岩, 魏孔熙, 张强
甘肃中医药大学第三附属医院，甘肃 白银 730900
Author(s):
SUI Yan, WEI Kongxi, ZHANG Qiang
The Third Affiliated Hospital of Gansu University of Chinese Medicine, Baiyin 730900, China
关键词:
毛囊炎; 马拉色菌; 中药外洗; 硫磺软膏; 血清炎症因子; IgE抗体
Keywords:
folliculitis; malassezia; herbs for external cleaning; sulphur ointment; serum inflammatory factors; IgE antibody
分类号:
R275.9
DOI:
10.12174/j.issn.2096-9600.2024.08.30
文献标志码:
B
摘要:
目的观察中药复方液外洗联合10%硫磺软膏外涂治疗马拉色菌毛囊炎的临床疗效。 方法将60例马拉色菌毛囊炎患者随机分为观察组与对照组，每组30例。观察组采用中药复方液外洗联合10%硫磺软膏外涂，对照组使用10%硫磺软膏外涂，连续治疗4周。观察两组临床疗效，于治疗前后采用酶联免疫吸附法测定两组患者血清白细胞介素6（interleukin-6，IL-6）、白细胞介素10（interleukin-6，IL-10）、白细胞介素18（interleukin-18，IL-18）水平，采用双抗体夹心法测定IgE抗体水平。 结果治疗后两组血清炎症因子IL-6、IL-10、IL-18水平均下降（P＜0.05），且观察组降低较对照组明显（P＜0.05）。治疗后两组血清IgE抗体水平较治疗前下降，观察组治疗前后比较，差异有统计学意义（P＜0.05）；对照组治疗前后比较，差异无统计学意义（P＞0.06）；治疗后观察组较对照组下降明显（P＜0.05）。 结论中药复方液外洗联合10%硫磺软膏外涂，可有效治疗马拉色菌毛囊炎，可消除红肿痒痛等症状，同时可降低炎症效应及抑制过激的免疫反应。
Abstract:
ObjectiveTo observe therapeutic effects of external herbal compound liquid and 10% sulphur ointment for external application in the treatment of malassezia folliculitis. MethodsSixty patients were randomly separated into the observation group and the control group with 30 cases in each group. Herbal compound liquid for external cleaning and 10% sulphur ointment for external application were administered to the observation group, and 10% sulphur ointment for external application to the control group, they were treated for four weeks consecutively. To observe clinical effects between both groups, ELISA method was adopted to detect the levels of IL-6, IL-10 and IL-18 in the two groups before and after the treatment, double-antibody sandwich ELISA was adopted to measure the levels of IgE antibody. ResultsAfter the treatment, the levels of IL-6, IL-10 and IL-18 lowered in the two groups (P<0.05), and the decrease of the observation group was more evident than the control group (P<0.05). After treating, the levels of IgE antibodies reduced than before treating in the two groups, the difference showed statistical meaning before and after the treatment (P<0.05); the difference has no statistical meaning in the control group before and after the treatment (P<0.05); after the treatment, the observation group lowered more obviously than the control group (P<0.05). ConclusionHerbal compound liquid for external cleaning and 10% sulphur ointment for external application could effectively treat malassezia folliculitis, relieve the symptoms including redness, swelling, itching and pain, meanwhile, reduce inflammatory effects and inhibit excessive immune response.

备注/Memo

备注/Memo:
眭岩（1972—），男，副主任医师。研究方向：难治性皮肤病的中西医结合治疗。E-mail：865459320@qq.com。甘肃省教育厅高等学校创新基金项目（2021B-167）。
更新日期/Last Update: 2024-08-15