[1]陈柏尧,苏燕婷,文彬,等.半夏泻心汤治疗慢性萎缩性胃炎研究概述[J].西部中医药,2023,36(01):149-152.[doi:10.12174/j.issn.2096-9600.2023.01.35]
 CHEN Boyao,SU Yanting,WEN Bin,et al.An Overview of the Treatment of Chronic Atrophic Gastritis by Banxia Xiexin Tang[J].Western Journal of Traditional Chinese Medicine,2023,36(01):149-152.[doi:10.12174/j.issn.2096-9600.2023.01.35]
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半夏泻心汤治疗慢性萎缩性胃炎研究概述
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年01期
页码:
149-152
栏目:
出版日期:
2023-01-15

文章信息/Info

Title:
An Overview of the Treatment of Chronic Atrophic Gastritis by Banxia Xiexin Tang
作者:
陈柏尧1, 苏燕婷1, 文彬2, 付蕾2, 邓鑫1,2
1.广西中医药大学,广西 南宁 530000
2.广西中医药大学附属瑞康医院,广西 南宁 530000
Author(s):
CHEN Boyao1, SU Yanting1, WEN Bin2, FU Lei2, DENG Xin1,2
1.Guangxi University of Chinese Medicine, Nanning 530000, China
2.Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530000, China
关键词:
慢性萎缩性胃炎半夏泻心汤作用机制综述
Keywords:
chronic atrophic gastritismechanismoverview
分类号:
R256.33
DOI:
10.12174/j.issn.2096-9600.2023.01.35
文献标志码:
A
摘要:
以半夏泻心汤为切入点,对半夏泻心汤治疗慢性萎缩性胃炎(chronic atrophic gastritis,CAG)的相关研究进行概述,指出大多数CAG的发生、发展与Hp感染密切相关,因此,抑制Hp及逆转胃癌前病变(precancerous lesion of gastric cancer,PLGC)成为治疗CAG的重要思路,半夏泻心汤治疗CAG有抑制Hp、逆转PLGC及修复、保护胃黏膜等作用,其治疗CAG的潜在生物学机制具有多成分-多靶点-多途径的特点,但仍需联合现代医学多中心、大规模地研究半夏泻心汤的作用机制,为半夏泻心汤治疗消化道疾病的药理学研究和临床应用提供更多理论依据。
Abstract:
By taking Banxia Xiexin Tang as the breakthrough point, and reviewing the relevant studies on the treatment of CAG with Banxia Xiexin Tang, it is pointed out that the onset and development of most of CAG are closely related to Hp infection, Hence inhibiting Hp and reversing PLGC have become the important thinking of treating CAG, and Banxia Xiexin Tang could inhibit Hp, reverse PLGC, repair and protect gastric mucosa in the treatment of CAG, its potential biological mechanism of treating CAG has the characteristics of multi-component, multi-target and multi-pathway, while multi-center large-scale studies on the mechanism of the prescription are still needed by combining with modern medicine, which could provide more theoretical basis for pharmacological research and clinical application of Banxia Xiexin Tang in the treatment of digestive tract diseases.

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备注/Memo

备注/Memo:
陈柏尧(1993—),男,硕士学位,医师。研究方向:消化系统疾病。国家自然科学基金(81860790,81660743);广西卫生计划委员会自筹课题(Z2016205)。
更新日期/Last Update: 2023-01-15