[1]朱若维,李雪菲,牛露娜,等.基于数据挖掘探讨国医大师治疗胸痹心痛痰瘀互结证用药规律及经验[J].西部中医药,2024,37(03):28-31.[doi:10.12174/j.issn.2096-9600.2024.03.06]
　ZHU Ruowei,LI Xuefei,NIU Luna,et al.TCM National Master's Medication Rules and Experience of the Treatment of Thoracic Obstruction and Cardiac Pain of Intermingled Phlegm and Blood Stasis Pattern Based on Data Mining[J].Western Journal of Traditional Chinese Medicine,2024,37(03):28-31.[doi:10.12174/j.issn.2096-9600.2024.03.06]
点击复制

基于数据挖掘探讨国医大师治疗胸痹心痛痰瘀互结证用药规律及经验
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年03期
页码:
28-31
栏目:
二次研究
出版日期:
2024-03-15

文章信息/Info

Title:
TCM National Master's Medication Rules and Experience of the Treatment of Thoracic Obstruction and Cardiac Pain of Intermingled Phlegm and Blood Stasis Pattern Based on Data Mining
作者:
朱若维, 李雪菲, 牛露娜, 邓秘, 郭惠怡, 荆鲁
中国中医科学院眼科医院，北京 100040
Author(s):
ZHU Ruowei, LI Xuefei, NIU Luna, DENG Mi, GUO Huiyi, JING Lu
Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China
关键词:
胸痹心痛; 痰瘀互结证; 冠心病; 数据挖掘; 国医大师
Keywords:
thoracic obstruction and cardiac pain; intermingled phlegm and blood stasis; coronary heart disease; data mining; TCM national master
分类号:
R256.22
DOI:
10.12174/j.issn.2096-9600.2024.03.06
文献标志码:
A
摘要:
目的探讨国医大师治疗胸痹心痛痰瘀互结证的用药规律及治疗经验。 方法以题目“胸痹心痛”“胸痹”“心痛”“冠心病”并包含120位国医大师姓名，和/或作者中包含国医大师姓名为检索式，检索中国知网、维普、万方等数据库，整理筛选后纳入胸痹心痛痰瘀互结证相关文献，文献中涉及的处方经中医传承辅助平台V3.0统计分析，总结国医大师的用药规律及其经验。 结果胸痹心痛痰瘀互结证以胸闷、胸痛为主症，伴有气短、乏力、眠差等次症；舌象以舌暗红，苔白腻为主；脉象以脉弦滑和脉细为主；高频药物主要有丹参、川芎、瓜蒌等；药物功效使用频次最多的依次是活血化瘀类、补虚类、理气类、化痰止咳平喘类及清热类等；使用频次最多的3组药对分别为瓜蒌-薤白、丹参-瓜蒌、丹参-党参，3个核心组合中以川芎、丹参、黄芪、郁金、瓜蒌（核心组合2）出现频次最多。 结论国医大师治疗胸痹心痛痰瘀互结证以活血化瘀、补气化痰为主，常用血府逐瘀汤、丹参饮、瓜蒌薤白半夏汤、温胆汤等方剂化裁加减，随证治之。
Abstract:
Objective: To investigate TCM national masters' medication rules and therapeutic experience in the treatment of thoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern. MethodsThe literature on thoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern was searched from CNKI, CQVIP, Wanfang and other databases, with the titles of "thoracic obstruction and cardiac pain", "thoracic obstruction" "cardiac pain", "coronary heart disease", including the names of 120 national masters of Chinese medicine, and/or the authors' names containing the names of the national masters of Chinese medicine as retrieval formula, and the papers were included after sorting and selecting, the prescriptions were analyzed statistically via traditional Chinese medicine inheritance support system (TCMISS V3.0) to summarize the national masters' medication rules and therapeutic experience. ResultsThoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern is mainly characterized by chest tightness and chest pain, accompanied by shortness of breath, fatigue, poor sleep and other secondary symptoms, demonstrating dark red tongue and white and greasy tongue fur, slippery string and thin pulse; the high-frequency drugs mainly include Danshen (Salviae miltiorrhizae radix et rhizoma), Chuanxiong (Chuanxiong rhizoma) and Gualou (Trichosanthis fructus) and others; the statistical analysis of the efficacy of the drugs showed that the drugs with the highest frequency of use were the types of activating blood and removing blood stasis, tonifying deficiency, regulating Qi, resolving phlegm and relieving cough and asthma, clearing away heat; the association cluster analysis showed that three most frequent drug combinations were Gualou-Xiebai (Allii macrostemonis bulbus), Danshen-Gualou, Danshen-Dangshen (Codonopsis radix) respectively, and three core combinations, among them, Chuanxiong, Danshen, Huangqi (Astragali radix), Yujin (Curcumae radix) and Gualou appeared the most frequently. ConclusionTCM national masters' treatment of thoracic obstruction and cardiac pain of intermingled phlegm and blood stasis pattern mainly adopts activating blood and removing blood stasis, tonifying Qi and resolving phlegm, the commonly-used prescription is Xuefu Zhuyu Tang, Danshen Yin, Gualou Xiebai Banxia Tang and Wendan Tang, modified in the application of the symptoms.

相似文献/References:

[1]牛嘉暄,赵英强,杨继,等.基于健脾化湿法论治胸痹心痛的研究进展[J].西部中医药,2023,36(05):158.[doi:10.12174/j.issn.2096-9600.2023.05.37]
　NIU Jiaxuan,ZHAO Yingqiang,YANG Ji,et al.Research Progress on the Treatment of Chest Pain and Heartache by Invigorating-spleen Resolving-dampness Method[J].Western Journal of Traditional Chinese Medicine,2023,36(03):158.[doi:10.12174/j.issn.2096-9600.2023.05.37]
[2]代昌波,张军,马一平.化痰散瘀汤治疗斑块型银屑病（痰瘀互结证）疗效观察及临床作用机制研究[J].西部中医药,2023,36(08):74.[doi:10.12174/j.issn.2096-9600.2023.08.18]
　DAI Changbo,ZHANG Jun,MA Yiping.Observation on Curative Effects of Resolving-phlegm Eliminating-stasis Decoction in the Treatment of Plaque Psoriasis of Phlegm and Blood Stasis Intermingling Pattern and Study on Clinical Mechanism[J].Western Journal of Traditional Chinese Medicine,2023,36(03):74.[doi:10.12174/j.issn.2096-9600.2023.08.18]

备注/Memo

备注/Memo:
朱若维（1996—），男，在读硕士研究生。研究方向：心血管疾病的中西医诊治。北京市中医药科技发展资金项目（JJ-2020-83）。
更新日期/Last Update: 2024-03-15