[1]明海霞,陈彦文,王强,等.甘肃金银花对小鼠红细胞免疫功能影响的实验研究*[J].西部中医药,2012,25(12):16-17.
 MING Hai-xia,CHEN Yan-wen,WANG Qiang,et al.Experimental Study of Gansu Honeysuckle on Immunologic Function of Erythrocytes in Mice[J].Western Journal of Traditional Chinese Medicine,2012,25(12):16-17.
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甘肃金银花对小鼠红细胞免疫功能影响的实验研究*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
25
期数:
2012年12期
页码:
16-17
栏目:
出版日期:
2012-12-15

文章信息/Info

Title:
Experimental Study of Gansu Honeysuckle on Immunologic Function of Erythrocytes in Mice
文章编号:
1004-6852(2012)12-0016-02
作者:
明海霞陈彦文王强董晓丽金戈李扬黄世佐
甘肃中医学院,甘肃 兰州 730000
Author(s):
MING Hai-xia, CHEN Yan-wen, WANG Qiang, DONG Xiao-li, JIN Ge, LI Yang, HUANG Shi-zuo
Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China
关键词:
甘肃金银花正品金银花流式细胞术红细胞免疫
Keywords:
Gansu honeysuckle native honeysuckle flow cytometry immunologic function of erythrocyte
分类号:
R285.5
文献标志码:
A
摘要:
目的:比较甘肃金银花与正品金银花对小鼠红细胞免疫功能的影响。方法:采用流式细胞技术对小鼠红细胞的免疫黏附功能(C3bR 受体和免疫复合物)进行测定,观察甘肃金银花与正品金银花对小鼠红细胞免疫功能影响的差异。结果:甘肃金银花和正品金银花干预的小鼠红细胞 C3bR 指数与病理性循环免疫复合物(IC)指数显著高于空白对照组(P<0.05),但甘肃金银花和正品金银花各浓度组之间无显著性差异。结论:甘肃金银花和正品金银花均可增加小鼠红细胞的免疫功能,即在红细胞免疫功能方面甘肃金银花与正品金银花具有相同的药用价值。
Abstract:
Objective: To compare the effects of Gansu honeysuckle and native one on immunologic function of red blood cells in mice. Method: Immunological and adhesive functions (C3bR receptor and immune complex) of erythrocytes in mice were detected by flow cytometry, the differences of Gansu honeysuckle and native one on immunologic function of erythrocytes in mice were observed and explored. Result: C3bR index and immune complex (IC)oferythrocytesinmiceof Gansu honeysuckle and native one groups were higher than that of blank group (P<0.05)and there was no significant difference in different concentrations between groups of Gansu honeysuckle and native one. Conclusion:Gansu honeysuckle and native one can enhance immunologic function of erythrocytes in mice, i.e.Gansu honeysuckle and native one have the same medicinal values on immunologic function of erythrocytes.

参考文献/References:

[1] 郭峰,虞紫茜,赵中平.红细胞免疫功能初步研究[J].中华麻醉学杂志,1982,62(12):715-716. [2] 王海滨,张景萍,沈茜,等.红细胞补体受体 1 型分子定量测定方法[J].中华医学检验杂志,1999,22(6):342-343. [3] 郭峰,钱宝华,闵碧荷.血液免疫学研究[M].上海:第二军医大学出版社,1998:1. [4] 李亚荣,杨沛霖.金银花有效成分检测方法研究进展[J].西部中医药,2012,25(6):109-110.

备注/Memo

备注/Memo:
收稿日期:2012-08-23 * 基金项目:甘肃中医学院中青年基金项目(编号 05ZQ-04) 作者简介:明海霞(1976—),女,博士研究生,副教授。研究方向:人体生理功能的辨证研究。
更新日期/Last Update: 1900-01-01