[1]王学琦,李丰华,张荣华,等.温肾汤治疗早期糖尿病肾病80例[J].西部中医药,2013,26(09):62-63.
　WANG Xueqi,LI Fenghua,ZHANG Ronghua,et al.WenShenTang for 80 Cases of Early Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(09):62-63.
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温肾汤治疗早期糖尿病肾病80例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年09期
页码:
62-63
栏目:
出版日期:
2013-09-15

文章信息/Info

Title:
WenShenTang for 80 Cases of Early Diabetic Nephropathy
文章编号:
1004-6852(2013)09-0062-02
作者:
王学琦，李丰华，张荣华，俞登虎
古浪县人民医院内科，甘肃 古浪 733100
Author(s):
WANG Xueqi, LI Fenghua, ZHANG Ronghua, YU Denghu
Department of Internal Medicine of Gulang County People′s Hospital, Gulang 733100, China
关键词:
糖尿病肾病; 温肾汤; 尿蛋白; 血脂
Keywords:
diabetic nephropathy;  WenShenTang;  proteinuria;  blood lipid
分类号:
R587.2
文献标志码:
B
摘要:
目的：观察温肾汤治疗早期糖尿病肾病（DN）的临床疗效。方法：80例早期DN患者在采用糖尿病教育、调节控制饮食、适当运动、药物控制血糖的基础上给予温肾汤，1剂/d，水煎分2次口服。4周为1疗程，连续治疗2个疗程后观察患者尿微量蛋白/肌酐（MA/Cr）、血β2微球蛋白（β2-MG）、尿β2-MG、尿α1微球蛋白（α1-MG）、血肌酐（SCr）、血浆纤维蛋白（FIB）、血脂[总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）]变化情况。结果：治疗后MA/Cr、血β2-MG、尿β2-MG、尿α1-MG、血SCr、血FIB均有减少（P＜0.05），TC、TG、LDL-C、HDL-C明显改善（P＜0.05）。结论：温肾汤能有效延缓早期DN的进展，减少尿蛋白，显著改善血脂。
Abstract:
Objective: To observe clinical effects of WenShenTang in treating early diabetic nephropathy (DN). Method: All 80 patients took WenShenTang on the foundation of diabetes education, diet regulation, proper exercise and blood glucose controlling through drugs, one dose per day, water decocted and taking twice. Four weeks were one course of treatment, and the changes of microalbuminuria/creatinine(MA/Cr), blood β2 microglobulin (β2-MG), urinary β2 microglobulin (β2-MG), urinary α1 microglobulin (α1-MG), serum creatinine(SCr), plasma fibrinogen (FIB), total cholesterol (TC), glycerin trilaurate (TG), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol(LDL-C) were observed after two consecutive courses of treatment. Result: After treating, MA/Cr, blood β2-MG, urinary β2-MG, urinary α1-MG, SCr and FIB were decreased (P＜0.05), TC, TG, LDL-C and HDL-C were improved obviously(P＜0.05). Conclusion: WenShenTang could effectively delay the development of early DN, reduce proteinuria and remarkably improve blood lipid.

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备注/Memo

备注/Memo:
收稿日期：2013-05-28 作者简介：王学琦（1963—），男，副主任医师。研究方向：心血管疾病的中西医诊治。
更新日期/Last Update: 2013-09-15