[1]刘安国,严兴科△,阚丽丽,等.铺灸疗法为主治疗强直性脊柱炎的Meta分析*[J].西部中医药,2013,26(12):51-54.
　LIU Anguo,YAN Xingke,KAN Lili,et al.Meta Analysis of Primary Treatment for Ankylosing Spondylitis by Long Snake Moxibustion[J].Western Journal of Traditional Chinese Medicine,2013,26(12):51-54.
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铺灸疗法为主治疗强直性脊柱炎的Meta分析*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年12期
页码:
51-54
栏目:
出版日期:
2013-12-15

文章信息/Info

Title:
Meta Analysis of Primary Treatment for Ankylosing Spondylitis by Long Snake Moxibustion
文章编号:
1004-6852(2013)12-0051-04
作者:
刘安国1，严兴科1△，阚丽丽2，董莉莉1，王军燕1
1甘肃中医学院针灸推拿系，甘肃 兰州 730000；2 甘肃中医学院中医医疗系
Author(s):
LIU Anguo1, YAN Xingke1△, KAN Lili2, DONG Lili1, WANG Junyan1
1 Department of Acupuncture and Massage in Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China; 2 Department of Traditional Chinese Medical Treatment in Gansu University of Traditional Chinese Medicine
关键词:
强直性脊柱炎; 铺灸; 药物铺灸; 长龙灸; 督灸; Meta分析
Keywords:
ankylosing spondylitis;  spreading moxibustion;  drug spreading moxibustion;  long dragon moxibustion;  moxibustion along Du meridian;  Meta analysis
分类号:
R593.23
文献标志码:
A
摘要:
目的：评价铺灸疗法治疗强直性脊柱炎(Ankylosing Spondylitis，AS)疗效的优越性、远期疗效及安全性。方法：计算机检索从2000年到2012年在中国知网(CNKI)、万方数据库(WF)中收录的有关铺灸疗法为主治疗AS的随机对照试验（randomized controlled trial，RCT）文献，对文献进行质量评价，并用Review Manager 5.1软件进行荟萃分析(Meta分析)。结果：总共纳入临床随机对照试验文献17篇，涉及患者共1 700名。Meta分析结果显示铺灸疗法治疗强直性脊柱炎的总体有效率优于口服西药疗法和单纯针刺疗法。与口服西药疗法比较，合并后效应指标RR=1.24，95%(Confidence Interval,CI)为(1.14，1.35)；与针刺疗法比较，合并后效应指标RR=1.27，95%CI(1.05，1.53)。结论：此次纳入研究文献质量普遍偏低：全部为单中心RCT研究，无多中心研究。其次，随机分组方法不够准确，多数文献未描述随访、脱落、远期疗效情况，诊断标准、疗效评价指标种类繁多，未能采取国际公认的标准。与口服西药疗法比较，铺灸疗法的总体有效率远高于口服西药疗法，疗效优越且复发率较低，无毒副作用，安全可靠；和针刺疗法比较，虽然药物铺灸疗法总体有效率较高，由于纳入研究数目较少，总病例数亦少，无远期疗效和安全性方面对比，其结果有待于大样本、多中心、方法科学的高质量临床研究加以验证。
Abstract:
Objective: To evaluate the advantages of long snake moxibustion in treating ankylosing spondylitis (AS)，theraprutic effect and the safety. Method: All the papers about randomized controlled trial of spreading moxibustion for AS were searched from 2000 to 2012 in CNKI and WanFang database, quality estimation was performed and all the papers were analyzed with Review Manager 5.1 software. Result: There were 17 pieces included, involving 1 700 patients. Meta analysis results indicated that total effective rate of spreading moxibustion in treating AS was superior to that of oral Western medicine and acupuncture therapy. Compared with oral Western medicine, merged effective indexe RR=1.24, 95%, (Confidence Interval, CI) was(1.14, 1.35); compared with the acupuncture therapy, merged effective indexe RR=1.27, 95%CI(1.05, 1.53). Conclusion: First of all, the included literature was in low quality and lacked multi-centered study. Next, randomized grouping method was inaccurate, the descriptions of follow-ups, drop and long-term effects weren't found in most of the papers, there were many indexes judging diagnostic standard and clinical efficacy but short of the standard. Total effective rate of spreading moxibustion was higher than that of oral Western medicine, the therapy, safe and reliable, could obtain better effects, with low recurrence rate and minor adverse reactions; although total effective rate of drug spreading moxibustion was higher, with a small number of samplings, less medical cases and lack of the comparisons in long-term effects and the safety, the results were needed to be verified by high quality RCT.

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备注/Memo

备注/Memo:
收稿日期：2013-02-26。*基金项目：2011年度甘肃省中医药科研项目资助(编号GZK-2011-6)。作者简介：刘安国(1987—)，男，硕士研究生。研究方向：针灸技术规范与临床疗效评价。△通讯作者：严兴科(1974—)，男，博士学位，教授。研究方向：针灸调节效应的生物学机制。
更新日期/Last Update: 2013-12-15