[1]张翠英,吉锋.解毒通脉胶囊治疗冠心病不稳定型心绞痛临床研究*[J].西部中医药,2015,28(01):1-3.
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解毒通脉胶囊治疗冠心病不稳定型心绞痛临床研究*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年01期
页码:
1-3
栏目:
出版日期:
2015-01-15

文章信息/Info

文章编号:
1004-6852(2015)01-0001-03
作者:
张翠英1，吉锋2
1 陕西中医学院附属医院心病科一病区，陕西 咸阳 712000； 2 陕西中医学院
关键词:
冠心病; 不稳定型心绞痛（UA）; 解毒通脉胶囊; 临床研究
分类号:
R541.4
文献标志码:
A
摘要:
目的:探讨解毒通脉胶囊治疗冠心病不稳定型心绞痛的临床疗效及作用机制。方法：将冠心病不稳定型心绞痛热毒痰瘀型患者60例按2∶1随机分为治疗组40例、对照组20例，对照组给予常规西医治疗，包括硝酸酯类药物、抗血小板聚集药物、他汀类药物，同时静脉滴注极化液等,并根据病情加用低分子肝素等药物,治疗组在此基础上加用解毒通脉胶囊口服，3粒/次,3次/d，2组疗程均为4周。结果：2组治疗后心绞痛疗效及硝酸甘油停减率比较差异有统计学意义(P＜0.05)；2组治疗后心电图疗效比较差异无统计学意义(P＞0.05)；2组治疗前后ET-1、NO组内比较差异有统计学意义(P＜0.05)，2组治疗后ET-1、NO组间比较，差异有统计学意义(P＜0.05)。结论：解毒通脉胶囊治疗冠心病不稳定型心绞痛可提高临床疗效，机制可能与降低患者血浆中ET-1含量，升高血清NO含量有关。

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备注/Memo

备注/Memo:
*基金项目：陕西省中医管理局中医药科研课题(编号2007074)。作者简介：张翠英(1961—)，女，硕士研究生导师，主任医师。研究方向：心血管疾病的中西医结合诊治。
更新日期/Last Update: 2015-01-15