[1]汪永国.参芪地黄汤对难治性肾病综合征患者肾功能的影响[J].西部中医药,2016,29(05):76-78.
　WANG Yongguo.The Effects of ShenQi DiHuang Tang on Renal Function of the Patients with Refractory Nephrotic Syndrome[J].Western Journal of Traditional Chinese Medicine,2016,29(05):76-78.
点击复制

参芪地黄汤对难治性肾病综合征患者肾功能的影响()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
29
期数:
2016年05期
页码:
76-78
栏目:
出版日期:
2016-05-15

文章信息/Info

Title:
The Effects of ShenQi DiHuang Tang on Renal Function of the Patients with Refractory Nephrotic Syndrome
文章编号:
1004-6852(2016)05-0076-03
作者:
汪永国
临泽县人民医院，甘肃 临泽 734200
Author(s):
WANG Yongguo
Linze County People′s Hospital, Linze 734200, China
关键词:
肾病综合征; 难治性; 参芪地黄汤; 肾功能
Keywords:
nephrotic syndrome;  refractory;  ShenQi DiHuang Tang;  renal function
分类号:
R246.1
文献标志码:
B
摘要:
目的:探讨参芪地黄汤对难治性肾病综合征患者肾功能的影响。方法：将150例患者随机分为观察组和对照组各75例。对照组给予对症处理及标准激素治疗；观察组在对照组基础上给予中药参芪地黄汤治疗，观察并记录2组患者治疗前后尿白蛋白量、内生肌酐清除率、尿素氮、血肌酐、血浆白蛋白等肾功能变化情况、中医证候积分情况及临床疗效和不良反应的发生情况。结果：尿白蛋白量、内生肌酐清除率、尿素氮、血肌酐、血浆白蛋白含量2组均较治疗前改善，差异有统计学意义(P＜0.05)，观察组改善更明显(P＜0.05)。中医证候积分治疗后2组均降低(P＜0.05)；观察组降低更明显(P＜0.05)。总有效率观察组为88.00%，对照组为65.30%，2组比较差异有统计学意义(P＜0.05)。不良反应发生率观察组为6.67%，对照组为20.00%，，2组比较差异有统计学意义(P＜0.05)。结论：参芪地黄汤治疗难治性肾病综合征，可改善患者肾功能，提高临床疗效，降低药物不良反应。
Abstract:
Objective: To explore the effects of ShenQi DiHuang Tang on renal function of the patients with refractory nephrotic syndrome. Methods: All 150 patients were randomly allocated to the observation group and the control group, 75 cases each group. The control group accepted corresponding therapy and standard hormone; the observation group took ShenQi DiHuang Tang on the foundation of the control group accepted. The changes of renal function including urinary albumin, endogenous creatinine clearance rate, usea nitrogen, serum creatinine, serum albumin and others, TCM symptome scales, clinical effects and the incidence of adverse reaction of both groups were observed and recorded. Results: The contents of urinary albumin, endogenous creatinine clearance rate, usea nitrogen, serum creatinine and serum albumin in both groups improved after treating compared with before treating obviously, and the difference had statistical meaning (P＜0.05), the improvement of the observation group was more obvious (P＜0.05). TCM symptom scales decreased significantly in both groups after treating (P＜0.05); and the decrease of the observation group was more significant (P＜0.05). Total effective rate of the observation group was 88.00%, higher than 65.30% of the control group, and the difference indicated statistical meaning (P＜0.05). The incidence of adverse reaction of the observation group was 6.67%, lower than 20.00% of the control group, and the difference presented statistical meaning (P＜0.05). Conclusion: ShenQi DiHuang Tang in treating of the patients with refractory nephrotic syndrome could improve renal function and clinical effects, decrease the incidence of drug adverse reaction.

相似文献/References:

[1]李卓慧.基于文献的肾病综合征蛋白尿中医证素分布及组合规律研究[J].西部中医药,2012,25(08):61.
　LI Zhuo-hui.Combination and Distribution of TCM Syndrome Elements of Proteinuria Induced by Nephritic Syndrome Based on Literature[J].Western Journal of Traditional Chinese Medicine,2012,25(05):61.
[2]王建明.中西医结合治疗小儿肾病综合征临床疗效分析[J].西部中医药,2013,26(07):92.
　WANG Jianming.Treatment for Children Suffering from Nephrotic Syndrome with Integrative Medicine[J].Western Journal of Traditional Chinese Medicine,2013,26(05):92.
[3]刘秀芳,马郑萍,马彩云.大剂量环磷酰胺冲击联合激素治疗难治性肾病综合征的护理探析[J].西部中医药,2013,26(11):122.
　LIU Xiufang,MA Zhengping,MA Caiyun.Nursing Exploration on Stosstherapy with Heavy Dose of Cyclophosphamide and Hormone in Treating Refractory Nephrotic Syndrome[J].Western Journal of Traditional Chinese Medicine,2013,26(05):122.
[4]张高林.马鸿斌教授治疗肾病综合征经验探析[J].西部中医药,2014,27(02):60.
　ZHANG Gaolin.Professor Ma Hongbin′s Experience of Treating Nephrotic Syndrome[J].Western Journal of Traditional Chinese Medicine,2014,27(05):60.
[5]张永科,马天寿.小柴胡汤联合多靶点激素治疗肾病综合征60例[J].西部中医药,2014,27(10):120.
[6]张继波,覃娜莎,熊有明,等.怡肾抗凝散穴位贴敷治疗肾病综合征60例[J].西部中医药,2014,27(12):9.
[7]李福荣.六味地黄汤联合激素治疗原发性肾病综合征30例[J].西部中医药,2014,27(12):89.
[8]刘明龙,高毅,赵健雄.赵健雄教授治疗肾病综合征经验总结[J].西部中医药,2015,28(04):45.
[9]杨世霞,康娟.补阳还五汤联合环磷酰胺治疗儿童激素抵抗性肾病综合征23例[J].西部中医药,2017,30(04):99.
　YANG Shixia,KANG Juan.BuYang HuanWu Tang Combined with Cyclophosphamide in the Treatment 23 Cases of Children with Steroid Resistant Nephrotic Syndrome[J].Western Journal of Traditional Chinese Medicine,2017,30(05):99.
[10]葛红娣,刘秀艳,翟力军.小柴胡汤加减对肾病综合征血清IGF-1及结合蛋白的影响[J].西部中医药,2019,32(04):1.
　GE Hongdi,LIU Xiuyan,ZHAI Lijun.Impact of Modified XiaoChaiHu Decoction on IGF-1 and Its Binding Protein in Nephrotic Syndrome[J].Western Journal of Traditional Chinese Medicine,2019,32(05):1.

备注/Memo

备注/Memo:
收稿日期：2015-12-07作者简介：汪永国(1976—)，男，主治医师。研究方向：中医内科。
更新日期/Last Update: 2016-05-15