[1]乔莉,郑慧,杨丽霞,等.基于CNKI数据挖掘分析黄芪多糖治疗糖尿病的文献特征和研究现状[J].西部中医药,2017,30(03):56-59.
　QIAO Li,ZHENG Hui,YANG Lixia,et al.Analysis of Literature Characteristics and Research Status of Astragalus Polysaccharides in Treating Diabetes Based on CNKI Data Mining[J].Western Journal of Traditional Chinese Medicine,2017,30(03):56-59.
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基于CNKI数据挖掘分析黄芪多糖治疗糖尿病的文献特征和研究现状()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年03期
页码:
56-59
栏目:
出版日期:
2017-03-15

文章信息/Info

Title:
Analysis of Literature Characteristics and Research Status of Astragalus Polysaccharides in Treating Diabetes Based on CNKI Data Mining
文章编号:
1004-6852(2017)03-0056-04
作者:
乔莉1，郑慧1，杨丽霞2，李雪英3，李钦4，刘铜华5
1 甘肃省中医院，甘肃 兰州 730050； 2 甘肃省中医药研究院；3 甘肃中医药大学；4 甘肃省中医学校；5 北京中医药大学
Author(s):
QIAO Li1, ZHENG Hui1, YANG Lixia2, LI Xueying3, LI Qin4, LIU Tonghua5
1 Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China; 2 Gansu Provincial Academy of Chinese Medicine; 3 Gansu University of Traditional Chinese Medicine; 4 Gansu Traditional Chinese Medicine School; 5 Beijing University of Traditional Chinese Medicine
关键词:
CNKI数据库; 黄芪多糖; 糖尿病; 文献
Keywords:
CNKI database;  astragalus polysaccharides;  diabetes;  literature
分类号:
R587.1
文献标志码:
A
摘要:
目的：通过数据挖掘，分析黄芪多糖治疗糖尿病的研究现状。方法：从中国知网(CNKI)数据库自建库起至2015年8月检索关键词“黄芪多糖”“糖尿病”，纳入黄芪多糖治疗糖尿病的全部文献，然后从文献年度分布、发表类型、学科分布、基金类型方面分析黄芪多糖治疗糖尿病的文献特征；从文献的主要单位及作者、主要疾病分布、研究类型方面分析黄芪多糖治疗糖尿病的研究现状。结果：从CNKI数据库文献检索发现黄芪多糖治疗糖尿病的研究共有257篇相关文献。其中196篇文献发表在学术期刊上，23篇为国内重要会议论文，17篇为优秀硕士学位论文，12篇为博士学位论文，少数分布在报纸、特色期刊及国际会议论文。从学科分布看，主要集中在中药学(152篇)和中医学(63篇)。国家自然科学基金资助最多(28篇)，其他分散在各省科研计划中。研究最多的机构是武汉大学(71篇)，其次是复旦大学附属华山医院(40)篇。研究内容主要针对糖尿病肾病(41篇)、糖尿病心血管病变(17篇)、糖尿病足(16篇)，主要以动物实验为主(114篇)，临床研究较少(8篇)。结论：黄芪多糖治疗糖尿病的研究呈逐年增长趋势，近10年增长迅速；在糖尿病方面药理作用广泛，可以治疗糖尿病肾病、糖尿病心肌病、糖尿病足、糖尿病视网膜病变等，尤其对糖尿病肾病作用显著。但大多数研究仅限于动物实验，临床研究不足，需要广大科研人员推进临床应用方面的研究。
Abstract:
Objective: To analyze the research status of Astragalus Polysaccharides (APS) in the treatment of diabetes through data mining. Methods: Keywords "APS" and "diabetes" were retrieved in the CNKI database from the day of database building to August，2015, and all literatures of APS in treating diabetes were included. Then, the literature characteristics of APS in the treatment of diabetes were analyzed from the aspects of annual distribution, publication type, subject distribution and fund types; the research status quo of APS in the treatment of diabetes mellitus was analyzed from the aspects of the main units and authors, the distribution of main diseases and the types of research. Results: Through searching in the literature, it was found that there were 257 relevant documents in total. Among them, 196 articles were published in the academic journals, 23 articles were the domestic important conference papers, and 17 articles were the excellent master’s theses, 12 ones were the doctoral dissertation. A small number of them were published in newspapers, characteristic periodicals and international conferences. From the perspective of subject distribution, they focused mainly on Chinese medicine (152 articles) and traditional Chinese medicine (63 articles). Beside, most of them were supported by the National Natural Science Foundation of China (28 articles), others were scattered in the provincial scientific research plans. What’s more, the institution who has the most researches was Wuhan University(71 articles), and the following one was Huashan Hospital Affiliated to Fudan University (40 articles). Moreover, the main contents of this study were diabetic nephropathy (41 articles), diabetic cardiovascular disease (17 articles) and diabetic foot (16 articles), mainly in animal experiments (114 articles) while less in clinical researches (8 articles). Conclusion: The study on the treatment of diabetes mellitus with APS is showing a trend of increasing year by year, and increasesrapidly in the recent ten years; It is widely used in the treatment of diabetes mellitus, diabetic nephropathy, diabetic cardiomyopathy, diabetic foot, diabetic retinopathy and so on, especially good for the diabetic nephropathy. Nevertheless, most studies are limited to animal experiments, and clinical research is insufficient. Therefore, more researchers need to promote the study of clinical application research.

相似文献/References:

[1]苏韫,刘永琦,颜春鲁,等.黄芪多糖对脑缺血再灌注大鼠脑组织Bcl-2、Bax蛋白及NO含量的影响[J].西部中医药,2016,29(03):10.
　SU Yun,LIU Yongqi,YAN Chunlu,et al.Influence of Astragalus Polysaccharides on the Contents of Bcl-2, Bax Protein and NO in the Brain Tissue of the Rats with Cerebral Ischemia Reperfusion[J].Western Journal of Traditional Chinese Medicine,2016,29(03):10.
[2]张玉梅,杨丽霞△,孟祥云.基于CNKI数据库分析葛根素治疗糖尿病的研究现状[J].西部中医药,2019,32(06):57.
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[3]杜雪洋,梁建庆,何建成,等.黄芪多糖的药理作用研究[J].西部中医药,2019,32(06):152.
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　LI Rui,WANG Yu.Research Progress of Anti-tumor Mechanism of Astragalus Polysaccharide[J].Western Journal of Traditional Chinese Medicine,2022,35(03):150.[doi:10.12174/j.issn.2096-9600.2022.09.32]
[5]王奇钰,吴晗,唐立垚,等.黄芪多糖对VEGF-C表达的抑制与结直肠癌细胞内淋巴管生成的相关性研究[J].西部中医药,2023,36(03):47.[doi:10.12174/j.issn.2096-9600.2023.03.09]
　WANG Qiyu,WU Han,TANG Liyao,et al.Correlation Study on the Inhibition of VEGF-C Expression by Astragalus Polysaccharides and Lymphangiogenesis in Colorectal Cancer Cells[J].Western Journal of Traditional Chinese Medicine,2023,36(03):47.[doi:10.12174/j.issn.2096-9600.2023.03.09]

备注/Memo

备注/Memo:
收稿日期：2016-03-08 *基金项目：国家自然科学基金(编号81202971)；甘肃省中医药管理局科研项目(编号GZK-2015-45，GZK-2016-48)。 作者简介：乔莉(1976—)，女，硕士学位，副主任中药师。研究方向：甘肃道地药材的开发与应用。
更新日期/Last Update: 2017-03-15