益气祛瘀化痰汤治疗脑动脉供血不足50例-《西部中医药》

文章信息/Info

Title:: Study of Nourishing Qi and Removing Blood Stasis and Phlegm Decoction in the Treatment of 50 Cases of Cerebral Arterial Insufficiency

Author(s):: XU Zhongbo1, FENG Xin2, TU Ren′an3; 1 Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China; 2 Maternal and Child Care Service Center of Jiangxi Province; 3 Traditional Chinese Medicine Hospital of Yugan County

Keywords:: insufficiency blood supply; cerebral artery; nourishing Qi and removing blood stasis and phlegm; transcranial doppler; hemorheology

摘要:: 目的：观察益气祛瘀化痰汤治疗脑动脉供血不足患者的临床疗效。方法：符合纳入标准的50例患者，给予益气祛瘀化痰汤治疗，连续治疗30天。治疗结束后判断临床疗效，比较治疗前后患者大脑中动脉、大脑前动脉、大脑后动脉平均血流速度和搏动指数、血液流变学的变化水平。结果：痊愈18例，显效15例，有效14例，无效3例，总有效率94.0%。全血黏度(高切、低切)、血浆黏度、红细胞变形指数、大脑中动脉、大脑前动脉、大脑后动脉平均血流速度和搏动指数等指标治疗后均有改善，与治疗前比较差异均有统计学意义(P＜0.05)。结论：益气祛瘀化痰汤能够通过扩张脑动脉，改善脑部血液循环、血流变水平，使脑动脉供血不足患者的症状得以缓解，且疗效明显。

Abstract:: Objective: To investigate the clinical effect of nourishing Qi and removing blood stasis and phlegm decoction in the treatment of patients with cerebral arterial insufficiency. Methods: 50 patients who were eligible for included criterion were treated by nourishing Qi and removing blood stasis and phlegm decoction, and the total treatment courses were 30 days. After finished the treatment courses, clinical effects were evaluated. Mean blood velocity, pulsatility indexes and change levels of hemorheology of middle cerebral artery, anterior cerebral artery and posterior cerebral artery were compared before and after treatment. Results: Recovery in 18 cases, markedly effective in 15 cases, effective in 14 cases, ineffective in 3 cases, and the total effective rate was 94.0%. Blood viscosity (high and low-shear), plasma viscosity, red cell deformability, mean blood velocity, pulsatility indexes of hemorheology of middle cerebral artery, anterior cerebral artery and posterior cerebral artery and other indexes all improved after treatment, compared with pre-treatment, the differences were statistically significant (P＜0.05). Conclusion: Nourishing Qi and and removing blood stasis and phlegm decoction can relieve symptoms of patients with cerebral arterial insufficiency and achieve significant effects by dilating cerebral arteries, improving cerebral blood circulation and blood rheology indexes of whole blood flow.