[1]黄东生,惠振亮.酸枣仁汤联合艾司唑仑治疗肝郁血虚型失眠43例[J].西部中医药,2017,30(10):93-95.
　HUANG Dongsheng,HUI Zhenliang.SuanZaoRen Decoction Jointed with Estazolam in Treating 43 Patients with Insomnia of Liver Depression and Blood Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2017,30(10):93-95.
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酸枣仁汤联合艾司唑仑治疗肝郁血虚型失眠43例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年10期
页码:
93-95
栏目:
出版日期:
2017-10-15

文章信息/Info

Title:
SuanZaoRen Decoction Jointed with Estazolam in Treating 43 Patients with Insomnia of Liver Depression and Blood Deficiency Pattern
文章编号:
1004-6852(2017)10-0093-03
作者:
黄东生1，惠振亮2
1 清涧县中医医院内科，陕西 清涧 718399； 2 陕西省中医医院脑病科
Author(s):
HUANG Dongsheng1, HUI Zhenliang2
1 Department of Internal Medicine, Qingjian County TCM Hospital, Qingjian 718399, China; 2 Department of Encephalopathy, Shaanxi Provincial TCM Hospital
关键词:
失眠症; 肝郁血虚型; 艾司唑仑; 酸枣仁汤
Keywords:
insomnia;  liver depression and blood deficiency pattern;  estazolam;  SuanZaoRen decoction
分类号:
R256.23
文献标志码:
B
摘要:
目的：观察酸枣仁汤联合艾司唑仑治疗肝郁血虚型失眠的临床疗效。方法：将83例肝郁血虚型失眠患者按照随机数字表法分为观察组（43例）及对照组（40例）。对照组使用艾司唑仑治疗，观察组患者在对照组治疗的基础上加用酸枣仁汤，2组均连续治疗1个月。观察2组治疗前后匹兹堡睡眠质量指数量表（PSQI）评分、睡眠状态自评量表（SRSS）评分、中医证候评分的变化情况及临床疗效和不良反应。结果：PSQI及SRSS评分治疗前后2组组内比较，差异有统计学意义（P＜0.05）；治疗后2组组间比较，差异也有统计学意义（P＜0.05）。总有效率观察组为88.37%，对照组为70.00%，2组比较差异有统计学意义（P＜0.05）。入睡困难、早醒、多梦、醒后难以入睡、情绪抑郁等中医证候单项评分治疗前后2组组内比较，差异有统计学意义（P＜0.05）；治疗后2组组间比较，差异也有统计学意义（P＜0.05）。不良反应发生率观察组为6.98%，对照组为27.50%，2组比较差异有统计学意义（P<0.05）。结论：酸枣仁汤联合艾司唑仑治疗肝郁血虚型失眠的临床疗效优于单用艾司唑仑治疗，可有效改善患者睡眠质量，安全性高。
Abstract:
Objective: To survey clinical effects of SuanZaoRen decoction combined with estazolam in treating insomnia of liver depression and blood deficiency pattern. Methods: All 83 patients were divided into the observation group (43 cases) and the control group (40 cases) according to random number table method. The patients in the control group were treated by estazolam, while the observation group took SuanZaoRen decoction on the foundation of the treatment the control group accepted, both groups were treated for one month consecutively. PSQI scales, SRSS scales, TCM syndrome scales, clinical effects and adverse reactions of both groups were observed before and after treating. Results: When PSQI scales and SRSS sales were compared before and after treating within the groups, and the difference had statistical meaning (P＜0.05); it had statistical meaning in the comparisons between both groups after treating (P＜0.05). Total effective rate of the observation group was 88.37%, higher than 70.00% of the control group, and the difference indicated statistical meaning (P＜0.05). The difference showed statistical meaning (P＜0.05) in the comparisons of single item scales of TCM syndromes such as difficulty falling asleep, early awakening, dreaminess, hard to sleep after waking up, depression and others; the difference presented statistical meaning in the comparisons between both groups after treating (P＜0.05). The incidence of adverse reaction in the observation group was 6.98%, lower than 27.50% of the control group, and the difference had statistical meaning (P＜0.05). Conclusion: Clinical effects of SuanZaoRen decoction combined with estazolam in treating insomnia of liver depression and blood deficiency pattern are superior to the effects of estazolam only, which could effectively improve sleep quality of the patients with high safety.

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备注/Memo

备注/Memo:
收稿日期：2017-04-25 作者简介：黄东生(1966—)，男，副主任医师。研究方向：脾胃病的中医诊治。
更新日期/Last Update: 2017-10-15