[1]张慧田,周知然,雷云霞△.益气除湿法联合美沙拉嗪治疗溃疡性结肠炎临床观察[J].西部中医药,2018,31(05):87-89.
　ZHANG Huitian,ZHOU Zhiran,LEI Yunxia.Clinical Observation on Qi-invigorating Damp-eliminating Method Combined with Mesalazine in Treating Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2018,31(05):87-89.
点击复制

益气除湿法联合美沙拉嗪治疗溃疡性结肠炎临床观察()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年05期
页码:
87-89
栏目:
出版日期:
2018-05-15

文章信息/Info

Title:
Clinical Observation on Qi-invigorating Damp-eliminating Method Combined with Mesalazine in Treating Ulcerative Colitis
文章编号:
1004-6852(2018)05-0087-03
作者:
张慧田，周知然，雷云霞△
新疆维吾尔自治区中医医院，新疆 乌鲁木齐 830000
Author(s):
ZHANG Huitian, ZHOU Zhiran, LEI Yunxia△
TCM Hospital Affiliated to Xinjiang Medical University, Urumqi 830000, China
关键词:
溃疡性结肠炎; 美沙拉嗪; 益气除湿
Keywords:
ulcerative colitis;  mesalazine;  Qi-invigorating damp-eliminating
分类号:
R574.62
文献标志码:
B
摘要:
目的：观察益气除湿法联合美沙拉嗪治疗溃疡性结肠炎的临床疗效。方法：将溃疡性结肠炎患者88例随机分为治疗组和对照组各44例，对照组服用美沙拉嗪肠溶片，治疗组在对照组基础上加用益气除湿法治疗。治疗3个月后比较2组患者临床症状改善情况、结肠黏膜病变评分变化情况及不良反应。结果：总有效率治疗组为86.4%，高于对照组的50.0%（P＜0.05），2组患者治疗后腹胀、腹泻、腹痛、脓血便、里急后重评分均较治疗前下降（P＜0.05），治疗组治疗后各症状评分较对照组下降明显（P＜0.05）；治疗组治疗后结肠镜下结肠黏膜病变评分较治疗前及对照组治疗后下降明显（P＜0.05）。结论：益气除湿法联合美沙拉嗪治疗溃疡性结肠炎临床疗效优于单纯西药治疗，而且不良反应少。
Abstract:
Objective: To observe clinical effects of Qi-invigorating damp-eliminating method and mesalazine in the treatment for ulcerative colitis (UC). Methods: All 88 UC patients were randomized into the treatment group and the control group, 44 cases each group, the patients in the control group were medicated with mesalazine enteric-coated tablets, and the ones in the treatment group with Qi-invigorating damp-eliminating prescription on the foundation of the therapy the control group accepted. Adverse reaction, the changes of colonic mucosal lesion scores and the improvements of clinical symptoms were compared in three months between both groups. Results: Total effective rate of the treatment group was 86.37%, significantly higher than 50.00% of the control group (P＜0.05), the scores of abdominal distension, diarrhea, abdominal pain, pus and blood stool, and tenesmus in both groups after treating decreased compared with before treating (P＜0.05), the decrease of the treatment group was more obvious than that of the control group notably after treating (P＜0.05), colonic mucosal lesion scores under the colonoscope in the treatment group after treating lowered remarkably compared with before treating and these of the control group after treating (P＜0.05). Conclusion: Clinical effects of Qi-invigorating damp-eliminating method and mesalazine in the treatment for UC are superior to these of only western medicine, and the therapy shows fewer adverse reactions.

相似文献/References:

[1]李明彦,刘召.三黄汤口服并灌肠治疗溃疡性结肠炎临床观察[J].西部中医药,2014,27(11):127.
[2]孙军刚,刘琦,吴巧凤△.针刺对溃疡性结肠炎Th17/Treg免疫平衡的调节作用[J].西部中医药,2015,28(01):129.
[3]杨斌,王碧霞.美沙拉嗪栓联合穴位贴治疗溃疡性结肠炎中期效果探讨[J].西部中医药,2015,28(05):112.
[4]张军,叶玉伟.中医药治疗溃疡性结肠炎研究进展概况[J].西部中医药,2013,26(12):150.
　ZHANG Jun,YE Yuwei.A Survey of TCM in Treating Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2013,26(05):150.
[5]陈晨.中药保留灌肠治疗急性期溃疡性结肠炎的研究[J].西部中医药,2014,27(05):135.
　CHEN Chen.Research on Retention Enema with Herbs in Treating Ulcerative Colitis at Acute Exacerbation Stage[J].Western Journal of Traditional Chinese Medicine,2014,27(05):135.
[6]李有成,严文有,陈俊英,等.加味阳和四神汤/浸膏剂治疗慢性溃疡性结肠炎疗效观察[J].西部中医药,2014,27(05):104.
　LI Youcheng,YAN Wenyou,CHEN Junying,et al.Observation on Modified YangHe SiShen Decoction or Extract in Treating Chronic Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2014,27(05):104.
[7]王福亭.致康胶囊对溃疡性结肠炎患者血清TNF-α、IL-6及CRP的影响[J].西部中医药,2016,29(02):100.
　WANG Futing.Influence of ZhiKang Capsules on Serum TNF-α, IL-6 and CRP of the Patients with Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2016,29(05):100.
[8]张亮,王玮,邱连利△.温通针法治疗脾肾阳虚型溃疡性结肠炎35例[J].西部中医药,2017,30(12):100.
　ZHANG Liang,WANG Wei,QIU Lianli.Warming Needling Method in Treating 35 Cases of Ulcerative Colitis of Spleen-kidney Yang-deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2017,30(05):100.
[9]周春芳.强肝软坚汤加味治疗溃疡性结肠炎机制研究[J].西部中医药,2018,31(03):97.
　ZHOU Chunfang.Study on the Mechanism of Modified Liver-strengthening Mass-softening Decoction in Treating Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2018,31(05):97.
[10]石磊,韩亚飞,贾博宜,等.清肠温中方对溃疡性结肠炎模型大鼠炎性因子的影响[J].西部中医药,2018,31(06):16.
　SHI Lei,HAN Yafei,JIA Boyi,et al.Effects of Intestine-clearing Middle Energizer-warming Prescription on Inflammatory Factors of TNBS - induced UC Rat Model[J].Western Journal of Traditional Chinese Medicine,2018,31(05):16.
[11]崔童.肠安康胶囊联合美沙拉嗪治疗溃疡性结肠炎疗效观察[J].西部中医药,2015,28(01):78.
[12]李丽梅,王永强.参苓白术散联合美沙拉嗪治疗溃疡性结肠炎临床观察[J].西部中医药,2021,34(10):124.[doi:10.12174/j.issn.2096-9600.2021.10.31]
　LI Limei,WANG Yongqiang.Clinical Observation on Shenling Baizhu Powder and Mesalazine in Treating Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2021,34(05):124.[doi:10.12174/j.issn.2096-9600.2021.10.31]
[13]苏海燕,陈怀霞,陈晓彤,等.四神丸合理中汤联合美沙拉嗪治疗溃疡性结肠炎作用机制研究[J].西部中医药,2023,36(01):92.[doi:10.12174/j.issn.2096-9600.2023.01.21]
　SU Haiyan,CHEN Huaixia,CHEN Xiaotong,et al.Study on the Mechanism of Sishen Pills, Lizhong Tang and Mesalazine in the Treatment of Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2023,36(05):92.[doi:10.12174/j.issn.2096-9600.2023.01.21]

备注/Memo

备注/Memo:
收稿日期：2017-08-04 作者简介：张慧田(1984—)，女，硕士学位，主治医师。研究方向：消化系统疾病的诊治。 △通讯作者：雷云霞(1975—)，女，博士学位，副主任医师。研究方向：脾胃病的临床与基础研究。
更新日期/Last Update: 2018-05-15