[1]王雁.黄芪党参葛根汤加减联合硫酸镁治疗妊娠期高血压64例[J].西部中医药,2018,31(06):96-98.
　WANG Yan.Treating 64 Cases of Gestational Hypertension by Modified HuangQi DangShen GeGen Decoction and Magnesium Sulphuricum[J].Western Journal of Traditional Chinese Medicine,2018,31(06):96-98.
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黄芪党参葛根汤加减联合硫酸镁治疗妊娠期高血压64例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年06期
页码:
96-98
栏目:
出版日期:
2018-06-15

文章信息/Info

Title:
Treating 64 Cases of Gestational Hypertension by Modified HuangQi DangShen GeGen Decoction and Magnesium Sulphuricum
文章编号:
1004-6852(2018)06-0096-03
作者:
王雁
兰州军区总医院安宁分院，甘肃 兰州 730070
Author(s):
WANG Yan
Anning Branch, Lanzhou General Hospital of Lanzhou Command, Lanzhou 730070, China
关键词:
妊娠期高血压; 黄芪党参葛根汤; 硫酸镁
Keywords:
gestational hypertension;  HuangQi DangShen GeGen decoction;  magnesium sulphuricum
分类号:
R714.24+6
文献标志码:
B
摘要:
目的：观察黄芪党参葛根汤联合硫酸镁注射液治疗妊娠期高血压的临床疗效。方法：将128例患者随机分为对照组和观察组，每组64例，对照组给予硫酸镁注射液治疗，观察组在此基础上给予黄芪党参葛根汤水煎分服，1剂/d。2组均治疗1周。观察2组临床疗效，检测脐动脉收缩压与舒张压比值(S/D)、C反应蛋白(CRP)浓度、血液黏度等常规产前指标，统计胎儿分娩方式、宫缩乏力、产后出血、胎儿窘迫和新生儿感染等产后指标发生率，评价临床用药的安全性。结果：对照组痊愈15例，显效22例，有效13例，无效14例，总有效率78.13%；观察组痊愈19例，显效25例，有效15例，无效5例，总有效率92.19%。观察组临床疗效优于对照组，差异有统计学意义(P＜0.05)。S/D、CPR、血液黏度、红细胞压积等指标同组治疗前后比较，差异有统计学意义(P＜0.05)；治疗后组间比较，差异也有统计学意义(P＜0.05)。观察组自然分娩率高于对照组，差异有统计学意义(P＜0.05)；宫缩乏力、产后出血、胎儿窘迫、新生儿感染等并发症发生率观察组均低于对照组，差异有统计学意义(P＜0.05)。结论：黄芪党参葛根汤联合硫酸镁注射液治疗妊娠期高血压临床疗效显著，可有效改善产前、产后等危险指标，药物安全性高。
Abstract:
Objective: To explore clinical effects of HuangQi DangShen GeGen decoction combined with magnesium sulphuricum injection in the treatment for gestational hypertension. Methods: All 128 patients were separated into 64 cases in the control group and 64 cases in the observation group, the control group were given magnesium sulphuricum injection, the observation group HuangQi DangShen GeGen decoction combined with magnesium sulphuricum injection, water decocted, one dose each day. Both groups were treated for one week. Clinical effects of both groups were observed, routine prenatal indexes such as blood viscosity, the concentrations of C-reactive protein (CRP), the ratio of systolic and diastolic blood pressure of umbilical artery (S/D) and others were detected, the incidences of postpartum indexes such as fetal delivery mode, uterine inertia, postpartum bleeding, fetal distress, infection of newborn and others were counted to assess the safety of clinical medication. Results: There were 15 cases cured, 22 cases markedly effective, 13 cases effective and 14 cases ineffective, total effective rate of the control group was 78.13%; 19 cases cured, 25 cases markedly effective, 15 cases effective and five cases ineffective, total effective rate of the observation group was 92.19%. The observation group was superior to the control group, and the difference had statistical meaning (P＜0.05). The difference had statistical meaning in the comparisons of S/D, CRP, blood viscosity and hematocrit between before and after treating in the same group (P＜0.05); the difference was statistically significant in the comparison between both groups after treating (P＜0.05). The observation group was higher than the control group in the rate of natural labor, and there was a significant difference (P＜0.05); the observation group was lower than the control group in the incidences of uterine inertia, postpartum bleeding, fetal distress, infection of newborn and others, and the difference was statistically significant (P＜0.05). Conclusion: HuangQi DangShen GeGen decoction combined with magnesium sulphuricum injection could obtain notable effects in the treatment for gestational hypertension, it could effectively improve prenatal and postpartum dangerous indexes with high drug safety.

备注/Memo

备注/Memo:
收稿日期：2017-11-20 作者简介：王雁(1980—)，女，主治医师。研究方向：产科疾病的临床治疗。
更新日期/Last Update: 2018-06-15