[1]钟秋红,王萍.正柴胡饮颗粒联合甲巯咪唑治疗甲状腺功能亢进疗效观察[J].西部中医药,2019,32(01):92-94.
　ZHONG Qiuhong,WANG Ping.Observation on Clinical Effects of ZhengChaiHuYin Granules and Methidathion in Treating Hyperthyroidism[J].Western Journal of Traditional Chinese Medicine,2019,32(01):92-94.
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正柴胡饮颗粒联合甲巯咪唑治疗甲状腺功能亢进疗效观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年01期
页码:
92-94
栏目:
出版日期:
2019-01-15

文章信息/Info

Title:
Observation on Clinical Effects of ZhengChaiHuYin Granules and Methidathion in Treating Hyperthyroidism
文章编号:
1004-6852(2019)01-0092-03
作者:
钟秋红，王萍
苏州市吴江区中医医院，江苏 苏州 215221
Author(s):
ZHONG Qiuhong, WANG Ping
Wujiang District TCM Hospital, Suzhou 215221, China
关键词:
甲状腺功能亢进; 正柴胡饮颗粒; 甲巯咪唑
Keywords:
hyperthyroidism;  ZhengChaiHuYin granules;  methidathion
分类号:
R265
文献标志码:
B
摘要:
目的：观察正柴胡饮颗粒联合甲巯咪唑治疗甲状腺功能亢进的临床疗效。方法：将甲状腺功能亢进患者80例按照随机数字表法分为观察组与对照组各40例，对照组口服甲巯咪唑，观察组在对照组基础上口服正柴胡饮颗粒，比较2组患者甲状腺激素变化情况、不良反应以及复发情况。结果：干预后2组患者血清游离三碘甲腺原氨酸(FT3)及血清游离甲状腺素(FT4)水平均低于干预前(P＜0.05)，促甲状腺激素(TSH)水平高于干预前(P＜0.05)；干预后观察组FT3及FT4水平低于对照组(P＜0.05)，TSH水平高于对照组(P＜0.05)。2组消化道不适、肝功能损伤、肾功能损伤及骨髓抑制等发生情况比较差异无统计学意义(P＞0.05)。观察组1年复发率、2年复发率及总复发率低于对照组(P＜0.05)。结论：正柴胡饮颗粒联合甲巯咪唑能有效调节甲状腺功能亢进患者甲状腺相关激素水平，治疗安全性高，不增加不良反应，能有效降低复发率。
Abstract:
Objective: To survey clinical effects of ZhengChaiHuYin granules combined with methidathion in the treatment for hyperthyroidism. Methods: Eighty patients were randomized into the observation group and the control group according to random number table method, 40 cases each group, the control group took methidathion, and the observation group ZhengChaiHuYin granules on the foundation of the therapy the control group accepted, the relapse conditions, adverse reaction and the changes of thyroid hormone of both groups were compared. Results: After the intervention, the levels of FT3 and FT4 of both groups were lower than before intervention(P＜0.05), the levels of TSH were higher than before intervention(P＜0.05), after treating, the levels of FT3 and FT4 of the observation group were lower than these of the control group after the intervention(P＜0.05), the levels of TSH were higher than these of the control group after the intervention (P＜0.05); there was no difference in the comparisons of gastrointestinal discomforts, liver function injury, renal function injury and arrest of bone marrow between both groups(P＞0.05); the observation group was less than the control group in relapse rate within one year and within two years (P＜0.05), and total relapse rate(P＜0.05). Conclusion: The combination of ZhengChaiHuYin granules and methidathion could effectively regulate the level of thyroid related hormone of the patients, which possesses high therapeutic safety, would not increase adverse reaction and effectively reduce the relapse rate.

相似文献/References:

[1]陈海红.甲状腺功能亢进症合并糖尿病58例护理体会[J].西部中医药,2015,28(12):131.
[2]聂晓燕.中西医结合护理在2型糖尿病合并甲状腺功能亢进患者中的应用效果[J].西部中医药,2019,32(04):120.
　NIE Xiaoyan.The Effects of Integrative Medicine Nursing Applied to the Patients Suffering Diabetes Mellitus Complicated with Hyperthyroidism[J].Western Journal of Traditional Chinese Medicine,2019,32(01):120.

备注/Memo

备注/Memo:
收稿日期：2018-06-20 作者简介：钟秋红(1977—)，女，主管药师。研究方向：药物临床应用。
更新日期/Last Update: 2019-01-15