[1]王娜莎,韩波.抗核抗体与椎-基底动脉供血不足患者中医证型的关系[J].西部中医药,2019,32(03):90-92.
　WANG Nasha,HAN Bo.Relationship between Antinuclear Antibodies and TCM Patterns of Vertebrobasilar Insufficiency[J].Western Journal of Traditional Chinese Medicine,2019,32(03):90-92.
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抗核抗体与椎-基底动脉供血不足患者中医证型的关系
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年03期
页码:
90-92
栏目:
出版日期:
2019-03-15

文章信息/Info

Title:
Relationship between Antinuclear Antibodies and TCM Patterns of Vertebrobasilar Insufficiency
文章编号:
1004-6852(2019)03-0090-03
作者:
王娜莎，韩波
辽宁中医药大学附属医院，辽宁 沈阳 110032
Author(s):
WANG Nasha, HAN Bo
The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China
关键词:
椎-基底动脉供血不足; 中医证型; 抗核抗体
Keywords:
vertebrobasilar insufficiency;  TCM patterns;  antinuclear antibodies
分类号:
R255.3
摘要:
目的：探讨抗核抗体(ANA)与椎-基底动脉供血不足(VBI)患者中医证型的关系。方法：采用间接免疫荧光法检测VBI组（106例）和健康对照组（30例）的血清ANA。结果：1)VBI组ANA阳性比例高于健康对照组，差异有统计学意义(P＜0.05)；2)VBI组患者各证型除痰湿中阻证组外，其余各证型组ANA阳性率均高于健康对照组，各证型ANA阳性比例高低依次为：气血亏虚证＞肾精不足证＞肝阳上亢证＞痰湿中阻证＞健康对照组；气血亏虚证、肾精不足证与健康对照组ANA阳性比例分布比较差异具有统计学意义(P＜0.05)。结论：VBI患者各证型与ANA阳性比例高低有一定联系，早期ANA检测可评估VBI患者是否存在免疫系统紊乱 情况。
Abstract:
Objective: To discuss the relationship between antinuclear antibodies (ANA) and TCM patterns of vertebrobasilar insufficiency (VBI). Methods: ANA in the serum of VBI group (106 cases) and healthy control group (30 cases) was detected using indirect immunofluorescence(IFL). Results: 1) VBI group was higher than healthy control group in ANA positive rate, and the difference had statistical meaning(P＜0.05); 2) VBI group was higher than healthy control group in ANA positive rates of different patterns except phlegm-damp obstruction pattern, the positive rates of ANA of different patterns ranked from high to low:Qi and blood deficiency pattern＞kidney-essence insufficiency pattern>liver-Yang hyperactivity pattern＞phlegm-damp obstruction pattern>healthy control group; the difference has been found when Qi and blood insufficiency pattern and kidney-essence insufficiency pattern were compared with healthy control group in ANA positive rate (P＜0.05). Conclusion: Different patterns of VBI patients show certain connections to ANA positive rates, early determination of ANA could be used to assess whether the disorders existed in immune system of VBI patients.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期：2018-01-23 *基金项目：辽宁省科学技术计划项目(编号2017010186-301)。 作者简介：王娜莎(1983—)，女，硕士学位，主治医师。研究方向：神经内科疾病的中西医结合诊治。
更新日期/Last Update: 2019-03-15