[1]刘彩霞,李娜△.MTX肌注联合中药口服治疗剖宫产瘢痕妊娠早期流产的临床价值[J].西部中医药,2019,32(06):111-113.
　LIU Caixia,LI Na.Clinical Value of Intramuscular Injection of MTX Combined with Oral Administration of Herbs in the Treatment for Early Abortion of Caesarean Scar Pregnancy[J].Western Journal of Traditional Chinese Medicine,2019,32(06):111-113.
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MTX肌注联合中药口服治疗剖宫产瘢痕妊娠早期流产的临床价值
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年06期
页码:
111-113
栏目:
出版日期:
2019-06-15

文章信息/Info

Title:
Clinical Value of Intramuscular Injection of MTX Combined with Oral Administration of Herbs in the Treatment for Early Abortion of Caesarean Scar Pregnancy
文章编号:
1004-6852(2019)06-0111-03
作者:
刘彩霞1，李娜2△
1 榆林市榆阳区中医医院，陕西 榆林 719000； 2 吴堡县医院
Author(s):
LIU Caixia 1, LI Na 2△
1 Yuyang District TCM Hospital of Yulin City, Yulin 719000, China; 2 Wubu County Hospital
关键词:
剖宫产瘢痕妊娠; MTX肌注; 中药; β-hCG水平; 不良反应
Keywords:
caesarean scar pregnancy;  intramuscular injection of MTX;  herbs;  the levels of β-hCG;  adverse reaction
分类号:
R714.21
文献标志码:
B
摘要:
目的：探讨MTX肌注联合中药口服治疗剖宫产瘢痕妊娠早期流产的临床价值。方法：将59例患者按照不同的治疗方式分为对照组（29例）和观察组（30例），对照组采用甲氨蝶呤(MTX)肌注治疗，观察组在对照组治疗的基础上给予中药口服治疗，比较2组治疗效果、临床症状恢复时间、治疗前后β-hCG水平变化及不良反应发生率。结果：杀胚成功率观察组为90.00%，对照组为72.41%，2组比较差异有统计学意义(P＜0.05)；出血持续时间、异常回声消失时间、血β-hCG达标时间及月经恢复时间2组比较，差异有统计学意义(P＜0.05)；血β-hCG水平治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后相同时间点2组组间比较，差异有统计学意义(P＜0.05。不良反应发生率2组比较，差异无统计学意义(P＞0.05)。结论：MTX肌注联合中药口服有助于提高杀胚成功率，改善患者的临床症状及β-hCG水平，且不增加不良反应。
Abstract:
Objective: To discuss clinical values of intramuscular injection of MTX combined with oral administration of herbs in the treatment for early abortion of caesarean scar pregnancy (CSP). Methods: All 59 patients were divided into the control group (29 cases) and the observation group (30 cases) according to different therapeutic ways, the control group accepted intramuscular injection of MTX, and the observation group took herbs orally on the foundation of the therapy the control group accepted, to compare therapeutic effects, the recovery time of clinical symptoms, the levels of β-hCG before and after treatment and the incidence of adverse reaction in both groups. Results: The success rate of killing the embryo in the observation group was 90.00%, higher than 72.41% of the control group, and the difference showed statistical meaning(P＜0.05); The difference had statistical meaning in menstruation recovery time, the time of β-hCG reaching the standard, disappearing time of abnormal echo and bleeding duration between both groups(P＜0.05); the difference showed statistical meaning in the levels of β-hCG within two groups before and after treating(P＜0.05); the difference presented statistical meaning between both groups after treating at the same time(P＜0.05). The difference had no statistical meaning in the incidence of adverse reaction between both groups(P＞0.05). Conclusion: Intramuscular injection of MTX combined with oral administration of herbs could help raise the success rate of killing the embryo, improve clinical symptoms of the patients and the levels of β-hCG, and it would not increase adverse reaction.

备注/Memo

备注/Memo:
收稿日期：2018-10-27*基金项目：西安市卫生局课题(编号J201601009)。作者简介：郭珍(1982—)，女，硕士学位，主治医师。研究方向：中西医结合治疗脑血管病。△通讯作者：盛刚(1980—)，男，硕士学位，主治医师。研究方向：针灸学。
更新日期/Last Update: 2019-06-15