中药口服与穴位贴敷治疗小儿支原体肺炎疗效观察-《西部中医药》

文章信息/Info

Title:: Observation on Clinical Effects of Oral TCM and Acupoint Application in the Treatment of Mycoplasma Pneumonia in Children

Author(s):: ZHU Xiaoqing1, GUO Yaxiong2; 1 Pediatric Department, Fufeng County TCM Hospital, Fufeng 722200, China; 2 Pediatric Department, First Affiliated Hospital of Shaanxi University of Chinese Medicine

Keywords:: mycoplasma pneumonia in children; syndrome scores; inflammatory factors; syndrome differentiation and treatment; TCM; acupoint application

摘要:: 目的：观察中药口服与穴位贴敷治疗小儿支原体肺炎的临床疗效。方法：将支原体肺炎患儿270例根据入院顺序随机分为对照组和研究组各135例，对照组患儿口服中药汤剂，研究组患儿在对照组基础上联合穴位贴敷，比较两组患儿临床疗效、治疗前后中医证候评分及炎性因子水平。结果：研究组总有效率高于对照组(P＜0.05)，研究组患儿临床症状及体征消失时间、住院时间均短于对照组，两组比较差异有统计学意义(P＜0.05)；治疗后两组患儿白细胞介素6(interleukin-6，IL-6)、白细胞介素8(interleukin-8，IL-8)、超敏C反应蛋白(high-sensitivity C-reactive protein，hs-CRP)及肿瘤坏死因子α(tumor necrosis factor α，TNF-α)水平较治疗前降低，且研究组低于对照组(P＜0.05)。结论：中药口服联合穴位贴敷可有效改善支原体肺炎患儿的临床症状及体征，抑制机体炎性反应效果优于口服中药汤剂。

Abstract:: Objective: To observe clinical effects of oral TCM and acupoint application in the treatment of mycoplasma pneumonia in children. Methods: A total of 270 children were randomized into the control group and the study group in light of admission order, 135 cases each group, the control group took TCM decoction, and the study group were given acupoint application, to compare clinical effects, TCM syndrome integrals and the levels of inflammatory factors between both groups. Results: Total effective rate of the study group was higher than that of the control group (P＜0.05), the study group was shorter than the control gorup in the disappearing time of clinical symptoms and body signs, and hospitalization time, and the difference showed statistical meaning (P＜0.05). after treating, the levels of IL-6, IL-8, hs-CRP and TNF-α reduced compared with these before treating in both groups, and the study group was shorter than the control group(P＜0.05). Conclusion: Oral TCM combined with acupoint application could effectively improve clinical symptoms and body signs, and inhibit body inflammatory reaction of the children.