[1]王文学.健脾止泻汤联合鞣酸蛋白酵母散治疗小儿腹泻临床观察[J].西部中医药,2020,33(08):109-111.[doi:10.12174/j.issn.1004-6852.2020.08.29]
　WANG Wenxue.Clinical Observation on Spleen-invigorating Diarrhea-stopping Decoction Joined with Albumin Tannate and Barm Powder in Treating Infantile Diarrhea[J].Western Journal of Traditional Chinese Medicine,2020,33(08):109-111.[doi:10.12174/j.issn.1004-6852.2020.08.29]
点击复制

健脾止泻汤联合鞣酸蛋白酵母散治疗小儿腹泻临床观察
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年08期
页码:
109-111
栏目:
出版日期:
2020-08-15

文章信息/Info

Title:
Clinical Observation on Spleen-invigorating Diarrhea-stopping Decoction Joined with Albumin Tannate and Barm Powder in Treating Infantile Diarrhea
文章编号:
1004-6852(2020)08-0109-03
作者:
王文学
扶风县中医医院中医儿科，陕西 扶风 722200
Author(s):
WANG Wenxue
Pediatric Department, Fufeng County TCM Hospital, Fufeng 722200, China
关键词:
腹泻; 健脾止泻汤; 鞣酸蛋白酵母散; 临床疗效; 免疫功能; 小儿
Keywords:
diarrhea;  spleen-invigorating diarrhea-stopping decoction;  albumin tannate and barm powder;  clinical effects;  immunologic function;  infants
分类号:
R723.11
DOI:
10.12174/j.issn.1004-6852.2020.08.29
文献标志码:
B
摘要:
目的：观察健脾止泻汤联合鞣酸蛋白酵母散治疗小儿腹泻的临床疗效及对患儿免疫功能的影响。方法：将198例患儿随机分为两组，对照组(98例)采用鞣酸蛋白酵母散进行治疗，观察组(100例)在对照组治疗的基础上治以健脾止泻汤，两组均连续治疗6天。比较两组临床有效率、临床症状改善情况、免疫功能相关指标、不良反应及复发情况。结果：总有效率观察组为96.00%(96/100)，对照组为85.71%(84/98)，两组比较差异有统计学意义(P＜0.05)。退热时间、腹痛缓解时间、排便恢复正常时间、呕吐缓解时间两组比较，差异有统计学意义(P＜0.05)。CD4+/CD8+、免疫球蛋白A(immunoglobulin A，IgA)及免疫球蛋白G(immunoglobulin G，IgG)水平治疗前后两组组内比较，差异有统计学意义(P＜0.05)；治疗后两组组间比较差异也有统计学意义(P＜0.05)。两组治疗期间均未出现明显不良反应；观察组患儿未见复发，对照组复发5例，复发率观察组显著低于对照组(χ2=5.234，P=0.028)。结论：健脾止泻汤联合鞣酸蛋白酵母散可显著提高小儿腹泻治疗的临床有效性，缩短症状恢复时间，提高患儿免疫力并降低复发率。
Abstract:
Objective: To observe clinical effects of spleen-invigorating diarrhea-stopping decoction joined with albumin tannate and barm powder in treating infantile diarrhea, and its influence on immunologic function. Methods: A total of 198 children were randomized into two groups, the control group (98 cases) adopted albumin tannate and barm powder, and the observation group (100 cases) were treated by spleen-invigorating diarrheastopping decoction based on the therapy the control group accepted, both groups were treated for six days consecutively. To compare clinical effective rate, the improvements of clinical symptoms, the related indexes of immunologic function, adverse reaction and the relapse conditions between both groups. Results: Total effective rate of the observation group was 96.00% (96/100), higher than 85.71% (84/98) of the control group, and the difference had statistical meaning (P＜0.05). The difference had statistical meaning in the time of bringing down fever, relief time of abdominal pain, the time of defecation restoring to normal, relief time of vomiting between both groups (P＜0.05). The difference was statistically significant in the levels of CD4+/CD8, IgA and IgG within two groups before and after treating (P＜0.05); the difference had statistical meaning between both groups after treating (P＜0.05). No obvious adverse reaction happened during therapeutic period in both groups; no relapse occured in the observation group, five cases relapsed in the control group, the relapse rate of the observation group was lower than that of the control group (χ2=5.234, P=0.028). Conclusion: Spleen-invigorating diarrhea-stopping decoction joined with albumin tannate and barm powder in treating infantile diarrhea could notably raise clinical effectiveness, shorten the recovery time of symptoms, lift the immunity and reduce relapse rate.

相似文献/References:

[1]柳树英,杨志华,原睿,等.微生态制剂与肠道菌群平衡观在小儿腹泻中的应用[J].西部中医药,2014,27(12):94.
[2]安娜,代二庆△,任会宁,等.葛根芩连汤及其加减方治疗小儿腹泻的统计分析[J].西部中医药,2015,28(07):68.
[3]吕富社.健脾止泻汤联合西药治疗婴幼儿秋季腹泻40例[J].西部中医药,2013,26(04):73.
　LV Fushe.Treatment for 40 Cases of Infantile Rotavirus Enteritis with JianPi ZhiXieTang Combined with Western Medicine[J].Western Journal of Traditional Chinese Medicine,2013,26(08):73.
[4]关亚珍,指导：张洪涛.矩阵针灸治疗脾虚型慢性腹泻 30 例临床观察[J].西部中医药,2013,26(03):62.
　GUAN Yazhen Director: ZHANG Hongtao.Matrix Acupuncture in Treating 30 Cases of Chronic Diarrhea of Spleen Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2013,26(08):62.
[5]钱丽,华海清△.华海清教授运用中药治疗索拉非尼所致腹泻的经验[J].西部中医药,2013,26(07):40.
　QIAN Li,HUA Haiqing.The Experience of Professor HUA Haiqing Using TCM to Diarrhea Induced by Sorafenib Tosylate[J].Western Journal of Traditional Chinese Medicine,2013,26(08):40.
[6]李新茹,张九云,何莉,等.中药穴位敷贴在婴幼儿腹泻中的应用[J].西部中医药,2016,29(05):131.
　LI Xinru,ZHANG Jiuyun,HE Li,et al.Herbal Acupoint Application Used to the Infants with Diarrhea[J].Western Journal of Traditional Chinese Medicine,2016,29(08):131.
[7]潘俊,茅渊△,费燕.中西药联合治疗功能性腹泻45例[J].西部中医药,2017,30(12):77.
　PAN Jun,MAO Yuan,FEI Yan.Herbs and Western Medicine in Treating 45 Cases of Functional Diarrhea[J].Western Journal of Traditional Chinese Medicine,2017,30(08):77.
[8]李新茹,张九云,何莉,等.裴氏健脾固元膏穴位敷贴联合复合乳酸菌治疗小儿腹泻疗效观察[J].西部中医药,2018,31(07):86.
　LI Xinru,ZHANG Jiuyun,HE Li,et al.Observation on Clinical Effects of Acupoint Application of Pei′s Spleen-invigorating Oringin-securing Plaster and Compound Lactobacillus in Treating Infantile Diarrhea[J].Western Journal of Traditional Chinese Medicine,2018,31(08):86.
[9]李亚兰.中西医结合护理对小儿腹泻护理效果的影响[J].西部中医药,2018,31(08):146.
　LI Yalan.Influence of Integrated Chinese and Western Medicine Nursing on Nursing Effects for Infantile Diarrhea[J].Western Journal of Traditional Chinese Medicine,2018,31(08):146.
[10]王方园,彭莹莹,杨振弢,等.从脾论治肠道菌群失调型慢性腹泻[J].西部中医药,2020,33(03):159.[doi:10.12174/j.issn.1004-6852.2020.03.45]
　WANG Fangyuan,PENG Yingying,YANG Zhentao,et al.Treating Intestinal Flora Disorder Chronic Diarrhea from Spleen[J].Western Journal of Traditional Chinese Medicine,2020,33(08):159.[doi:10.12174/j.issn.1004-6852.2020.03.45]

备注/Memo

备注/Memo:
收稿日期：2019-08-13作者简介：王文学(1977—)，男，副主任医师。研究方向：儿科疾病的中医诊治。
更新日期/Last Update: 2020-08-15