通腑泄浊法对腹腔高压患者分泌型免疫球蛋白A的影响-《西部中医药》

文章信息/Info

Title:: Effects of Bowel-freeing Turbidity-eliminating Method on sIgA in Patients with Intra-abdominal Hypertension

作者:: 白雪松¹, 林鸿峰², 李长辉¹, 袁硕¹, 张东伟¹, 齐文诚¹; 1.辽宁中医药大学附属医院，辽宁沈阳 110032
2.朝阳市第二人民医院

Author(s):: BAI Xuesong¹, LIN Hongfeng², LI Changhui¹, YUAN Shuo¹, ZHANG Dongwei¹, QI Wencheng¹; 1.The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China
2.The Second People′s Hospital of Chaoyang

Keywords:: intra-abdominal hypertension; intraperitoneal pressure; bowel-freeing turbidity-eliminating method; sIgA

摘要:: 目的观察通腑泄浊法对腹腔高压患者分泌型免疫球蛋白A（secretory immunoglobulin A，sIgA）的影响。方法将144例腹腔高压患者按腹腔高压发生的先后顺序，随机分为观察组和对照组，每组72例。给予对照组西药治疗，观察组在对照组治疗基础上给予通腑泄浊法治疗。比较两组腹腔内压、腹围差、腹腔灌注压、急性生理与慢性健康评分（acute physiology and chronic health evaluation，APACHE Ⅱ）及粪sIgA水平。结果治疗后两组腹腔内压、腹围差、腹腔灌注压及APACHEⅡ值均降低，sIgA水平明显升高，治疗前后组内比较及治疗后组间比较，差异均有统计学意义（P＜0.05）。结论通腑泄浊法治疗腹腔高压患者，可明显缓解其临床症状，提高肠黏膜分泌sIgA的水平。

Abstract:: ObjectiveTo observe the effects of bowel-freeing turbidity-eliminating method on sIgA in the patients with intra-abdominal hypertension(IAH). MethodsAll 144 patients were allocated to the observation group and the control group randomly according to the sequence of occurrence of abdominal hypertension, 72 cases in each group. The control group adopted Western medicine, and the observation group bowel-freeing turbidity-eliminating method based on Western medicine. To compare intraperitoneal pressure, abdominal circumference difference, intraperitoneal perfusion pressure, APACHEII and the levels of fecal sIgA between both groups. ResultsAfter the treatment, intraperitoneal pressure, abdominal circumference difference, intraperitoneal perfu-sion pressure, APACHEII values lowered in both groups, the levels of sIgA lifted notably, the differences were statistically significant within two groups before and after treating and between both groups after treating (P<0.05). ConclusionBowel-freeing turbidity-eliminating method for IAH patients could notably relieve clinical symptoms remarkably and raise the secretion of sIgA in intestinal mucosa.