[1]闫起,周忠光,杨波,等.麻木治疗方剂用药规律分析[J].西部中医药,2021,34(07):72-76.[doi:10.12174/j.issn.2096-9600.2021.07.18]
　YAN Qi,ZHOU Zhongguang,YANG Bo,et al.Analysis on the Medication Rules of Therapeutic Prescriptions for Numbness[J].Western Journal of Traditional Chinese Medicine,2021,34(07):72-76.[doi:10.12174/j.issn.2096-9600.2021.07.18]
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麻木治疗方剂用药规律分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年07期
页码:
72-76
栏目:
出版日期:
2021-07-15

文章信息/Info

Title:
Analysis on the Medication Rules of Therapeutic Prescriptions for Numbness
作者:
闫起1,2, 周忠光1, 杨波1, 梁华1, 李泽光2, 赵福红1, 姜北1
1.黑龙江中医药大学，黑龙江 哈尔滨 150040
2.黑龙江中医药大学附属第一医院
Author(s):
YAN Qi1,2, ZHOU Zhongguang1, YANG Bo1, LIANG Hua1, LI Zeguang2, ZHAO Fuhong1, JIANG Bei1
1.Heilongjiang University of Chinese Medicine, Harbin 150040, China
2.First Affiliated Hospital, Heilongjiang University of Chinese Medicine
关键词:
麻木; 《中医方剂大辞典》; 中医传承辅助系统; 用药规律
Keywords:
numbness; TCMISS; medication rules
分类号:
R587.2
DOI:
10.12174/j.issn.2096-9600.2021.07.18
摘要:
目的分析《中医方剂大辞典》中治疗麻木的方剂用药规律。 方法筛选《中医方剂大辞典》所载治疗麻木的方剂，将方剂信息录入中医传承辅助系统，基于关联规则分析、改进的互信息法、复杂系统熵聚类及无监督的熵层次聚类等数据挖掘方法对《中医方剂大辞典》中治疗麻木的方剂用药规律进行分析。 结果共筛选出内服方111首，涉及药物247味，使用频次大于10的药物有38味，最常用的药物包括当归、防风、羌活、人参、白芍、甘草、川芎、黄芪、白术、天麻等；得到常用药物组合19个，如防风-羌活、当归-羌活、当归-白芍、人参-当归等；挖掘出可能的隐性规律药物核心组合，得到用于新方聚类的药物组合7组，并进一步组合得到7首新处方；通过以方测证揭示麻木是以气血亏虚为本，风寒湿邪及痰、瘀为标的病证。 结论治疗麻木的方剂以补气实卫，养血和营为本，以祛风通络，化痰行瘀为标。
Abstract:
ObjectiveTo analyze the medication rules of the prescription for numbness in the dictionary of traditional Chinese medicine prescriptions. MethodsAfter screening the prescriptions of treating numbness recorded in the dictionary of traditional Chinese medicine prescriptions, the information of the prescriptions were typed into TCMISS, to analyze the medication rules of the prescription for numbness in the dictionary of traditional Chinese medicine prescriptions based on data mining methods including association rules analysis, improved mutual information method, entropy clustering of complex system and unsupervised entropy hierachical clustering. ResultsA total of 111 oral prescriptions were selected, involving 247 drugs, and 38 drugs were used more than 10 times, the most commonly used drugs include Danggui (Chinese Angelica), Fangfeng (Divaricate Saposhnikovia Root), Qianghuo (Rhizoma et Radix Notopterygii), Renshen (Ginseng Root), Baishao (Paeonia lactiflora), Gancao (Radix Glycyrrhiza), Chuanxiong (Rhizoma Chuanxiong), Huangqi (Radix astragali), Baizhu (Largehead Atractylodes Rh), Tianma (Rhizom Gastrodiae), etc; 19 commonly used drug combinations were obtained, such as Fangfeng-qianghuo, Danggui-qianghuo, Danggui-Baishao, Renshen-Danggui, and others; the possible recessive core drug combinations were excavated, seven drug combinations were obtained for new prescription clustering eventually, to get seven new prescriptions; numbness is the syndrome of Qi and blood deficiency as the root cause, wind, cold and dampness, phlegm and stasis as the superificial cause revealed by formula test. ConclusionThe prescription for numbness is based on supplementing Qi and strengthening defensive Qi, nourishing blood and harmonizing the nutrient, dispelling wind and clearing collaterals, removing phlegm and blood stasis as the superificial cause.

备注/Memo

备注/Memo:
闫起（1989—），男，博士学位，在站博士后，主治医师。研究方向：衰老及营养代谢相关病证的方剂配伍规律研究，风湿免疫系统疾病的防治。国家自然科学基金项目（81473563）；黑龙江省应用技术研究与开发计划项目（GA20C017）。
更新日期/Last Update: 2021-07-15