[1]李玲,李菁.基于“肝肾同源”理论探讨OPG/RANKL/RANK信号系统在骨转移癌痛中的调控机制[J].西部中医药,2022,35(06):149-152.[doi:10.12174/j.issn.2096-9600.2022.06.37]
　LI Ling,LI Jing.OPG/RANKL/RANK Signaling Regulation Mechanism of Cancer-induced Bone Pain Based on "the Same Source of Liver and Kidney" Theory[J].Western Journal of Traditional Chinese Medicine,2022,35(06):149-152.[doi:10.12174/j.issn.2096-9600.2022.06.37]
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基于“肝肾同源”理论探讨OPG/RANKL/RANK信号系统在骨转移癌痛中的调控机制
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年06期
页码:
149-152
栏目:
研究进展
出版日期:
2022-06-15

文章信息/Info

Title:
OPG/RANKL/RANK Signaling Regulation Mechanism of Cancer-induced Bone Pain Based on "the Same Source of Liver and Kidney" Theory
作者:
李玲1, 李菁2
1.上海中医药大学附属曙光医院，上海 201203
2.湖南中医药大学第一附属医院
Author(s):
LI Ling1, LI Jing2
1.Shuguang Hospital Affiliated to Shanghai University of TCM, Shanghai 201203, China
2.The First Hospital of Hunan University of Chinese Medicine
关键词:
骨转移癌痛; 肝肾同源; OPG/RANKL/RANK信号系统
Keywords:
cancer-induced bone pain; the same source of liver and kidney; OPG/RANKL/RANKsignaling system
分类号:
R733.3
DOI:
10.12174/j.issn.2096-9600.2022.06.37
文献标志码:
A
摘要:
从肝肾同源理论的应用出发，结合骨保护素（osteoprotegerin，OPG）/核因子受体活化因子NF-κB配体（receptor activator of NF-κB ligand，RANKL）/NF-κB受体活化因子（receptor activator for NF-κB，RANK）信号系统在骨代谢中的调控机制，阐释肝肾同源理论应用于临床的客观分子生物学依据，更好地指导临床。
Abstract:
Objective molecular biological evidence of applying "the same source of liver and kidney" is explained on the foundation of the application of the theory, combined with the regulatory mechanism of OPG/RANKL/RANK signaling system in bone metabolism, in order to better guide clinical prevention and treatment of bone metastasis cancer pain.

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备注/Memo

备注/Memo:
李玲（1998—），女，在读硕士研究生。研究方向：肿瘤疾病的中西医结合诊治及研究。2018年度湖南中医药大学校级科研基金项目（2018XJJJ54）。
更新日期/Last Update: 2022-06-24