[1]房庆鹏,王宗杰,于若卉,等.中药外耳道灌洗治疗真菌性耳道炎疗效观察及对耳道环境菌群的影响[J].西部中医药,2023,36(01):116-119.[doi:10.12174/j.issn.2096-9600.2023.01.27]
　FANG Qingpeng,WANG Zongjie,YU Ruohui,et al.Clinical Effects of External Auditory Canal Lavage with TCM in Treating Fungal Otitis Externa and Its influence on Environmental Microflora of Ear Canal[J].Western Journal of Traditional Chinese Medicine,2023,36(01):116-119.[doi:10.12174/j.issn.2096-9600.2023.01.27]
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中药外耳道灌洗治疗真菌性耳道炎疗效观察及对耳道环境菌群的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年01期
页码:
116-119
栏目:
出版日期:
2023-01-15

文章信息/Info

Title:
Clinical Effects of External Auditory Canal Lavage with TCM in Treating Fungal Otitis Externa and Its influence on Environmental Microflora of Ear Canal
作者:
房庆鹏1, 王宗杰1, 于若卉1, 高春2, 褚俊链1
1.沧州中西医结合医院，河北 沧州 061001
2.沧县医院，河北 沧县 061000
Author(s):
FANG Qingpeng1, WANG Zongjie1, YU Ruohui1, GAO Chun2, CHU Junlian1
1.Cangzhou Hospital of Integrated TCM-WM, Cangzhou 061001, China
2.Cangxian County Hospital, Cangxian 061000, China
关键词:
真菌性耳道炎; 耳道菌群; 中药灌洗; 临床疗效
Keywords:
fungal otitis externa; ear canal microflora; herbal lavage; clinical effects
分类号:
R276.1
DOI:
10.12174/j.issn.2096-9600.2023.01.27
文献标志码:
B
摘要:
目的探讨中药外耳道灌洗治疗真菌性耳道炎的临床疗效及对耳道环境菌群的影响。 方法将真菌性耳道炎患者120例随机分成观察组与对照组各60例。对照组采用常规耳道清理联合滴耳液耳浴治疗并护理，观察组在对照组基础上采用中药灌洗液进行外耳道负压灌洗。治疗2个月后观察两组疗效、血清炎症因子水平、治疗前后真菌菌群变化以及不良反应发生情况。 结果观察组总有效率为83.33%，高于对照组的75.00%，差异具有统计学意义（P＜0.05）；治疗后两组患者血清白细胞介素1和白细胞介素6水平均较治疗前降低，观察组下降更明显（t=8.331，7.435，P＜0.001）；治疗后观察组患者耳道曲霉属和白色念珠菌序列数较对照组减少（t=7.331，7.535，P＜0.001）；两组不良反应比较差异无统计学意义（P＞0.05）。 结论中药外耳道灌洗护理治疗能降低真菌性耳道炎患者炎症因子水平与真菌菌群含量，效果优于常规耳道清理联合滴耳液耳浴，且具有良好安全性。
Abstract:
ObjectiveTo survey clinical effects of external auditory canal lavage with TCM in the treatment of fungal otitis externa and its influence on environmental microflora of ear canal. MethodsAll 120 patients were randomized into the observation group and the control group with 60 cases in each group. The control group adopted routine ear canal cleaning and ear drops ear bath, and the observation group accepted negative pressure lavage with herbal lavage solution based on the therapy the control group accepted. Both groups were treated for two months. To survey therapeutic effects, the levels of serum inflammatory factors, the changes of fungal consortium before and after treatment and the incidence of adverse reaction between both groups. ResultsTotal effective rate of the observation group was 83.33%, higher than 75.00% of the control group, and the difference had statistical meaning (P<0.05); after the treatment, the levels of IL-1 and IL-6 of both groups were lower than these before the treatment, the decrease of the observation group was more remarkable (t=8.331, 7.435, P<0.001); after the treatment, the sequence number of aspergillus and candida albicans of the observation group decreased compared with that of the control group (t=7.331, 7.535, P<0.001); the difference had no statistical meaning in side effects between both groups (P>0.05). ConclusionExternal auditory canal lavage with TCM could decrease the levels of inflammatory factors and the contents of fungal consortium in the treatment of fungal otitis externa, and its effects are superior to these of routine ear canal cleaning and ear drops ear bath, presenting good safety.

备注/Memo

备注/Memo:
房庆鹏（1985—），男，主管护师。研究方向：真菌性外耳道炎的治疗护理。
更新日期/Last Update: 2023-01-15