[1]顾笑颜,林昭伶,钟悦,等.三阴型乳腺癌中医体质分布的Meta分析[J].西部中医药,2023,36(02):48-52.[doi:10.12174/j.issn.2096-9600.2023.02.11]
　GU Xiaoyan,LIN Zhaoling,ZHONG Yue,et al.Meta Analysis of TCM Constitution Distribution of Triple-negative Breast Cancer Patients[J].Western Journal of Traditional Chinese Medicine,2023,36(02):48-52.[doi:10.12174/j.issn.2096-9600.2023.02.11]
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三阴型乳腺癌中医体质分布的Meta分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年02期
页码:
48-52
栏目:
出版日期:
2023-02-15

文章信息/Info

Title:
Meta Analysis of TCM Constitution Distribution of Triple-negative Breast Cancer Patients
作者:
顾笑颜1, 林昭伶1, 钟悦1, 黄梅2
1.广州中医药大学第一临床医学院，广东 广州 510405
2.广州中医药大学第一附属医院，广东 广州 510405
Author(s):
GU Xiaoyan1, LIN Zhaoling1, ZHONG Yue1, HUANG Mei2
1.First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, China
2.The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China
关键词:
乳腺癌; 三阴型; 中医体质; Meta分析
Keywords:
breast cancer; triple negative; TCM constitutions; Meta analysis
分类号:
R737.9
DOI:
10.12174/j.issn.2096-9600.2023.02.11
文献标志码:
A
摘要:
目的采用循证医学系统评价研究方法，检索、纳入所有通过对三阴型乳腺癌与中医体质相关性的临床研究文献进行Meta分析，研究三阴型乳腺癌人群的体质分布特点，为中医防治三阴型乳腺癌提供更高级别的循证医学证据。 方法检索国内外6个数据库中三阴型乳腺癌与中医体质相关性的临床研究。运用STATA 13.0统计学软件，根据异质性检验结果，以随机效应模型或固定效应模型合并数据。用漏斗图分析潜在的发表偏倚。 结果共9项研究符合纳入标准，三阴型乳腺癌患者各中医体质类型的比例及95%置信区间依次为气郁质20%（13%～27%）、气虚质18%（14%～23%）、血瘀质14%（9%～20%）、阳虚质12%（5%～21%）、阴虚质10%（6%～15%）、痰湿质9%（7%～12%）、湿热质8%（5%～10%）、平和质3%（0%～9%）、特禀质0%（0%～1%）。 结论气郁质、气虚质、血瘀质和阳虚质是三阴型乳腺癌患者的主要体质类型和危险因素。
Abstract:
ObjectiveTo conduct a Meta analysis of all the clinical research literature about the relationships between triple-negative breast cancer and TCM constitutions after searching and including the papers, and to study the distributions of the constitutions of the people suffering triple-negative breast cancer, so as to provide a higher level evidence-based medical evidence for TCM prevention and therapy of the disease. MethodsClinical studies on the relationship between triple-negative breast cancer and TCM constitutions were searched from six databases at home and abroad, STATA 13.0 statistical software was used to combine data with random effects model or fixed effect model according to the heterogeneity test results. Potential publication bias was analyzed using funnel plots. ResultsAll nine studies met the inclusion standard, the proportions and 95% confidence interval of TCM constitution types in patients with triple-negative breast cancer are Qi-stagnation constitution, 20% (13%~27%), Qi deficiency constitution 18% (14%~23%), blood stasis constitution, 14% (9%~20%), Yang deficiency constitution 12% (5%~21%), Yin deficiency constitution 10% (6%~15%), phlegm damp constitution 9% (7%~12%), damp heat constitution 8% (5%~10%), mild constitution 3% (0%~9%), and special constitution 0%(0%~1%). ConclusionQi stagnation constitution, Qi deficiency constitution, blood stasis constitution and Yang deficiency constitution are the main constitution types of the patients with triple negative breast cancer and risk factors.

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备注/Memo

备注/Memo:
顾笑颜（1994—），女，硕士学位。研究方向：乳腺疾病的中医药防治。广东省科技计划项目（2019A141405045）。
更新日期/Last Update: 2023-02-15