[1]周舒梅,龚卓群,李夏.中药穴位敷贴辅助治疗气阴两虚夹瘀型老年糖尿病肾病疗效观察[J].西部中医药,2023,36(07):117-120.[doi:10.12174/j.issn.2096-9600.2023.07.29]
 ZHOU Shumei,GONG Zhuoqun,LI Xia.Clinical Observation on Acupoint Application of Chinese Medicine as Adjunctive Therapy in the Treatment of Senile Diabetic Kidney Disease of Qi and Yin Deficiency Intermingled with Blood Stasis Pattern[J].Western Journal of Traditional Chinese Medicine,2023,36(07):117-120.[doi:10.12174/j.issn.2096-9600.2023.07.29]
点击复制

中药穴位敷贴辅助治疗气阴两虚夹瘀型老年糖尿病肾病疗效观察
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年07期
页码:
117-120
栏目:
出版日期:
2023-07-15

文章信息/Info

Title:
Clinical Observation on Acupoint Application of Chinese Medicine as Adjunctive Therapy in the Treatment of Senile Diabetic Kidney Disease of Qi and Yin Deficiency Intermingled with Blood Stasis Pattern
作者:
周舒梅, 龚卓群, 李夏
六安市中医院肾病一科,安徽 六安 237000
Author(s):
ZHOU Shumei, GONG Zhuoqun, LI Xia
First Department of Nephrology, Lu'an Hospital of Traditional Chinese Medicine, Lu'an 237000, China
关键词:
糖尿病肾病血糖肾功能穴位敷贴氯沙坦钾片老年人
Keywords:
diabetic kidney diseaseblood glucoserenal functionacupoint applicationlosartan potassium tablesthe elderly
分类号:
R102
DOI:
10.12174/j.issn.2096-9600.2023.07.29
文献标志码:
B
摘要:
目的观察中药穴位敷贴辅助治疗气阴两虚夹瘀型老年糖尿病肾病(diabetic kidney disease,DKD)的疗效。 方法将110例老年2型DKD(Ⅲ期、Ⅳ期)患者采用随机数字表法分为对照组和观察组各55例。对照组在常规治疗基础上口服氯沙坦钾片;观察组在对照组基础上予中药穴位敷贴辅助治疗。治疗8周后观察两组患者血糖水平、肾功能、气阴两虚夹瘀证症状评分及临床疗效。 结果两组治疗后气阴两虚夹瘀证症状评分及空腹血糖(fasting blood glucose,FPG)、餐后2h血糖(2-hour postprandial blood glucose,2h PG)、糖化血红蛋白(glycosylated hemoglobin,HbAlc)均低于治疗前(P<0.01),观察组低于对照组(P<0.01)。治疗后两组患者24 h尿蛋白定量、尿白蛋白/肌酐比、血尿素氮、血肌酐低于治疗前,肾小球滤过率高于治疗前(P<0.01),观察组改善更明显(P<0.01);观察组总有效率高于对照组(P<0.05)。 结论在西医常规治疗基础上中药穴位敷贴能有效抑制老年DKD患者血糖水平,改善患者肾功能和中医证候。
Abstract:
ObjectiveTo observe clinical effects of acupoint application of Chinese medicine in the treatment of senile diabetic kidney disease(DKD) of Qi and Yin deficiency intermingled with blood stasis pattern as adjunctive therapy. MethodsA total of 110 senile patients suffering type two DKD (Ⅲ and Ⅳ stages) were allocated to the control group and the observation group using random number table method, with 55 cases in each group. The control group orally took losartan potassium tables on the foundation of conventional therapy; the observation group accepted acupoint application of Chinese medicine based on the therapy the control group received. To observe the levels of blood glucose, renal function, symptom scores of Qi and Yin deficiency intermingled with blood stasis pattern and curative effects after eight weeks of the treatment. ResultsAfter the treatment, symptom scores of Qi and Yin deficiency intermingled with blood stasis pattern, FPG, 2hPG, HbAlc of both groups were lower than these before the treatment (P<0.01), the observation group was lower than the control group (P<0.01). After the treatment, 24 h urinary protein quantification, urine albumin/creatinine ratio, blood urea nitrogen and serum creatinine of both groups were lower than these before the treatment, glomerular filtration rate higher than that before the treatment (P<0.01), the improvements of the observation group were more noticeable (P<0.01); total effective rate of the observation group was higher than that of the control group (P<0.05). ConclusionOn the foundation of conventional therapy of Western medicine, acupoint application of Chinese medicine could effectively inhibit the levels of blood glucose, improve renal function and TCM syndrome.

相似文献/References:

[1]林晓芬,黄燕璇.益肾汤联合厄贝沙坦及胰激肽原酶治疗早期糖尿病肾病的疗效观察[J].西部中医药,2013,26(07):68.
 LIN Xiaofen,HUANG Yanxuan.Clinical Observation on YiShenTang Combined with Irbesartan and Pancreatic Kininogenase in the Treatment for Early Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(07):68.
[2]王学琦,李丰华,张荣华,等.温肾汤治疗早期糖尿病肾病80例[J].西部中医药,2013,26(09):62.
 WANG Xueqi,LI Fenghua,ZHANG Ronghua,et al.WenShenTang for 80 Cases of Early Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(07):62.
[3]任芳,徐厚谦△.黄芪注射液治疗糖尿病肾病有效性及安全性的系统评价[J].西部中医药,2014,27(01):77.
 REN Fang,XU Houqian.Systematic Review of the Effectiveness and Safety of HuangQi Injection in Treating Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2014,27(07):77.
[4]丁夏楠,许筠△,苏建平,等.益肾逐瘀方治疗糖尿病肾病蛋白尿37例[J].西部中医药,2014,27(04):96.
 DING Xianan,XU Jun,SU Jianping,et al.Treatment for Proteinuria of 37 Patients with Diabetic Nephropathy by Kidney-invigorating Stagnation-dispelling Prescription[J].Western Journal of Traditional Chinese Medicine,2014,27(07):96.
[5]肖远莉.循证护理的优效性及影响因素分析———来自终末期糖尿病肾病患者血液透析的证据[J].西部中医药,2014,27(08):127.
[6]周雨聪,指导:刘召.红灵五黄汤治疗2型糖尿病90例[J].西部中医药,2015,28(04):99.
[7]刘涛.缬沙坦联合复方丹参滴丸对早期2型糖尿病肾病患者尿微量白蛋白的影响[J].西部中医药,2015,28(05):106.
[8]连琯,史晓伟.当归补血汤合金水宝治疗早期糖尿病肾病16例临床观察[J].西部中医药,2013,26(06):68.
 LIAN Guan,SHI Xiaowei.Clinical Observation on DangGui BuXueTang and JinShuiBao in Treating 16 Cases of Early Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(07):68.
[9]任芳,徐厚谦△.黄芪注射液治疗糖尿病肾病随机对照试验报告质量评价[J].西部中医药,2013,26(12):1.
 REN Fang,XU Houqian.Quality Evaluation of the Report for Randomized Controlled Trials of HuangQi Injection in Treating Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(07):1.
[10]朱苗蕊,指导:金智生.糖脂平治疗早期糖尿病肾病60例疗效观察*[J].西部中医药,2013,26(03):74.
 ZHU Miaorui,Director: JIN Zhisheng.Clinical Observation on TangZhiPing in Treating 60 Cases of Early Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(07):74.
[11]王永军,石良静,范正超,等.益气养阴通络方对Ⅲ期糖尿病肾病患者免疫功能的影响[J].西部中医药,2021,34(10):111.[doi:10.12174/j.issn.2096-9600.2021.10.27]
 WANG Yongjun,SHI Liangjing,FAN Zhengchao,et al.Effects of Qi-benefiting Yin-nourishing Collaterals-dredging Prescription on Immunological Function in Patients Suffering Diabetic Nephropathy at Stage Ⅲ[J].Western Journal of Traditional Chinese Medicine,2021,34(07):111.[doi:10.12174/j.issn.2096-9600.2021.10.27]
[12]吕翠岩,郑爽,贾晓蕾,等.参芪地黄汤化裁方对早期糖尿病肾病患者血糖及尿蛋白的影响[J].西部中医药,2021,34(09):51.[doi:10.12174/j.issn.2096-9600.2021.09.14]
 LYU Cuiyan,ZHENG Shuang,JIA Xiaolei,et al.Effects of Modified Prescription of Shenqi Dihuang Decoction on Blood Glucose and Urinary Protein in Early Diabetic Kidney Disease[J].Western Journal of Traditional Chinese Medicine,2021,34(07):51.[doi:10.12174/j.issn.2096-9600.2021.09.14]
[13]张璇,姜睿斌,张晓菊,等.地黄配伍玄参对糖尿病肾病大鼠微循环障碍的影响[J].西部中医药,2023,36(10):31.[doi:10.12174/j.issn.2096-9600.2023.10.06]
 ZHANG Xuan,JIANG Ruibin,ZHANG Xiaoju,et al.Effects of Dihuang Compatible with Xuanshen on Microcirculatory Disorders in Diabetic Nephropathy Rats[J].Western Journal of Traditional Chinese Medicine,2023,36(07):31.[doi:10.12174/j.issn.2096-9600.2023.10.06]

备注/Memo

备注/Memo:
周舒梅(1980—),女,主管护师。研究方向:肾病护理。安徽省卫生厅中医药科研计划(2012zy105)。
更新日期/Last Update: 2023-07-15