[1]陈存龙,樊园园,郭慧君.益气通络方对丘脑型脑卒中感觉障碍患者血清炎症因子与血脂的影响[J].西部中医药,2023,36(09):97-100.[doi:10.12174/j.issn.2096-9600.2023.09.21]
　CHEN Cunlong,FAN Yuanyuan,GUO Huijun.Influence of Yiqi Tongluo Prescription on Serum Inflammatory Factors and Blood Lipid in Patients with Thalamic Sensory Disorder[J].Western Journal of Traditional Chinese Medicine,2023,36(09):97-100.[doi:10.12174/j.issn.2096-9600.2023.09.21]
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益气通络方对丘脑型脑卒中感觉障碍患者血清炎症因子与血脂的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年09期
页码:
97-100
栏目:
出版日期:
2023-09-15

文章信息/Info

Title:
Influence of Yiqi Tongluo Prescription on Serum Inflammatory Factors and Blood Lipid in Patients with Thalamic Sensory Disorder
作者:
陈存龙1, 樊园园2, 郭慧君1
1.东部战区总医院秦淮医疗区，江苏 南京 210000
2.南京市雨花台区铁心桥社区卫生服务中心，江苏 南京 210000
Author(s):
CHEN Cunlong1, FAN Yuanyuan2, GUO Huijun1
1.Qinhuai Medical District, Eastern Theater General Hospital, Nanjing 210000, China
2.Tiexinqiao Community Health Service Center of Yuhuatai District, Nanjing 210000, China
关键词:
脑卒中; 丘脑型感觉障碍; 炎症因子; 血脂; 益气通络方
Keywords:
stroke; thalamic sensory disorder; inflammatory factors; blood lipid; prescription
分类号:
R243
DOI:
10.12174/j.issn.2096-9600.2023.09.21
文献标志码:
B
摘要:
目的探讨益气通络方对丘脑型脑卒中感觉障碍患者血清炎症因子及血脂的影响。 方法将丘脑型脑卒中患者118例随机分两组各59例，对照组采用常规治疗，包括生活方式干预、药物治疗、物理疗法及其他对症治疗，观察组在此基础上加益气通络方，治疗4周后比较两组患者临床疗效，治疗前后Fugl-meyer评分、Berg平衡量表（berg balance scale，BBS）评分、美国国立卫生研究院卒中量表（national institute of health stroke scale，NIHSS）评分及血清肿瘤坏死因子α（tumor necrosis factor-α，TNF-α）、白细胞介素6（Interleukin-6，IL-6）、甘油三酯（triglyceride，TG）、总胆固醇（total cholesterol，TC）水平，并记录不良反应。 结果总有效率对照组为79.66%（47/59），观察组为93.22%（55/59），差异有统计学意义（P＜0.05）。与治疗前相比，两组患者治疗后Fugl-meyer评分、BBS评分均升高，NIHSS评分及血清TNF-α、IL-6与TC、TG降低；与对照组比较，观察组患者治疗后Fugl-meyer评分、BBS评分升高，NIHSS评分及血清TNF-α、IL-6与TC、TG降低，差异有统计学意义（P＜0.05）。治疗期间两组均无不良反应出现。 结论益气通络方治疗丘脑型脑卒中感觉障碍疗效确切，可改善患者感觉、平衡及神经功能，降低血脂和炎症因子水平。
Abstract:
ObjectiveTo discuss the influence of Yiqi Tongluo prescription on serum inflammatory factors and blood lipid in patients with thalamic sensory disorder (TSD). MethodsAll 118 patients suffering thalamic stroke were randomized into two groups, with 59 cases in each group, the control group adopted conventional therapy, including lifestyle, drug treatment, physiotherapy and other symptomatic treatment, and the observation group took Yiqi Tongluo prescription orally based on the therapy the control group accepted, after four weeks of the treatment, to compare clinical effects between both groups, Fugl-meyer scores, BBS scores, NIHSS scores, the levels of IL-6, TG and TC before and after the treatment, to record adverse reaction in the two groups. ResultsThe effective rate of the control group was 79.66% (47/59), lower than 93.22% (55/59) of the observation group, and the difference had statistical meaning (P<0.05). Compared with before the treatment, Fugl-meyer scores and BBS scores lifted in the two groups after the treatment, NIHSS scores and the levels of TNF-α, IL-6, TC and TG lowered; compared with the control group, Fugl-meyer scores and BBS scores were higher, NIHSS scores and the levels of serum TNF-α and IL-6, TC and TG were lower in the observation group after the treatment, and the difference had statistical meaning (P<0.05). No adverse reaction occurred in both groups during therapeutic periods. ConclusionYiqi Tongluo prescription could obtain definite clinical effects in the treatment of TSD, it could improve sensory, balance and nerve function, reduce the levels of blood lipid and inflammatory factors.

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备注/Memo

备注/Memo:
陈存龙（1988—），男，主治医师。研究方向：内科杂病的中医药诊疗。北京希思科临床肿瘤与研究基金会资助（Y-MX2014-067）。
更新日期/Last Update: 2023-09-15