[1]任鹏,武兵兵,曹璐,等.穴位埋线疗法治疗原发性高血压有效性的Meta分析[J].西部中医药,2024,37(11):56-62.[doi:10.12174/j.issn.2096-9600.2024.11.13]
　REN Peng,WU Bingbing,CAO Lu,et al.The Effectiveness of Acupoint Catgut Embedding in the Treatment of Essential Hypertension: a Meta-analysis[J].Western Journal of Traditional Chinese Medicine,2024,37(11):56-62.[doi:10.12174/j.issn.2096-9600.2024.11.13]
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穴位埋线疗法治疗原发性高血压有效性的Meta分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年11期
页码:
56-62
栏目:
二次研究
出版日期:
2024-11-15

文章信息/Info

Title:
The Effectiveness of Acupoint Catgut Embedding in the Treatment of Essential Hypertension: a Meta-analysis
作者:
任鹏1,2, 武兵兵1,2, 曹璐1,2, 赵信科1,2, 刘凯1,2
1.甘肃中医药大学，甘肃 兰州 730000
2.甘肃中医药大学循证医学中心，甘肃 兰州 730000
Author(s):
REN Peng1,2, WU Bingbing1,2, CAO Lu1,2, ZHAO Xinke1,2, LIU Kai1,2
1.Gansu University of Chinese Medicine, Lanzhou 730000, China
2.Evidence-based Medical Center, Gansu University of Chinese Medicine, Lanzhou 730000, China
关键词:
原发性高血压; 穴位埋线; 有效性; Meta分析
Keywords:
essential hypertension; acupoint catgut embedding; effectiveness; Meta analysis
分类号:
R255.3
DOI:
10.12174/j.issn.2096-9600.2024.11.13
文献标志码:
A
摘要:
目的系统评价穴位埋线疗法治疗原发性高血压的疗效。 方法计算机检索PubMed、The Cochrane Library、Embase、Web of Science、WanFang Data、维普（China science and technology journal database，VIP）、中国知网（China National knowledge infrastructure，CNKI）和中国生物医学文献数据库（China biology medicine disc，CBM）数据库，搜集有关原发性高血压的随机对照试验（randomized controlled trial，RCT），检索时限均从建库至2021年6月1日。由两名研究者独立筛选文献，提取资料并评价纳入研究的偏倚风险后，采用RevMan 5.3软件进行Meta分析。 结果共纳入12个RCT，包括1022例患者。Meta分析结果显示：试验组的有效率（OR=3.71，95%CI：2.62～5.27，P＜0.000 01）、收缩压（MD=-5.84，95%CI：-9.39～-2.28，P=0.001）、舒张压（MD=-4.61，95%CI：-6.93～-2.28，P=0.0001）、甘油三酯（MD=-0.06，95%CI：-0.08～-0.04，P＜0.000 01）、高密度脂蛋白胆固醇（MD=-0.01，95%CI：-0.02～-0.00，P=0.004）、低密度脂蛋白胆固醇差异（MD=0.09，95%CI：0.03～0.14，P=0.001）、体质量指数（Body Mass Index，BMI）（MD=-2.51，95%CI：-4.64～-0.37，P=0.02）、中医证候积分水平（MD=-6.08，95%CI：-10.9～-1.27，P=0.01）均优于对照组，差异具有统计学意义。 结论现有证据表明，穴位埋线疗法治疗原发性高血压患者的疗效优于常规治疗。但受研究数量和质量限制，上述结论尚需开展更多高质量的研究予以验证。
Abstract:
ObjectiveTo systematically assess clinical effects of acupoint catgut embedding in the treatment of essential hypertension (EH). MethodsRandomized controlled trial (RCT) of EH were retrieved from PubMed, The Cochrane Library, Embase, Web of Science, Wanfang data, VIP, CNKI and CBMdisc, and the time limit ranged between the establishment of the database to June 1, 2021. Two researchers independently screened the literature, extracted the data and assessed the risk of bias of the included studies, RevMan 5.3 software was adopted to perform Meta analysis. ResultsThe study has included 12 RCTs, involving 1022 patients. The results of Meta analysis showed that: the effective rate (OR=3.71, 95%CI:2.62-5.27, P<0.000 01), systolic pressure (MD=-5.84, 95%CI:-9.39--2.28, P=0.001), diastolic pressure (MD=-4.61, 95%CI:-6.39--2.28, P=0.0001), triglyceride (MD=-0.06, 95%CI:-0.08--0.04, P<0.000 01), high density lipoprotein cholesterol (MD=-0.01, 95%CI:-0.02--0.00, P=0.004), low density lipoprotein cholesterol (MD=0.09, 95%CI:0.03-0.14, P=0.001), BMI (MD=-2.51, 95%CI:-4.64--0.37, P=0.02) and TCM syndrome integrals (MD=-6.08, 95%CI:-10.9--1.27, P=0.01) of the experiment group were better than these of the control group, and the difference had statistical meaning. ConclusionThe existing evidence shows that the efficacy of acupoint catgut embedding in the treatment of EH is better than that of routine therapy. The above conclusions need to be verified by more high-quality trials due to the limitations in the quantity and quality of the included studies.

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备注/Memo

备注/Memo:
任鹏（1995—），女，硕士学位。研究方向：内科常见疾病的中西医结合防治。国家中医药循证能力建设项目（2019XZZX-XXG002）。
更新日期/Last Update: 2024-11-15