[1]潘浩宇,刘志春,张春花,等.肠道微生物诱导胆囊结石形成机制的研究进展[J].西部中医药,2024,37(12):120-123.[doi:10.12174/j.issn.2096-9600.2024.12.28]
　PAN Haoyu,LIU Zhichun,ZHANG Chunhua,et al.Research Progress of the Mechanism of Gallbladder Calculus Formation Induced by Gut Microorganisms[J].Western Journal of Traditional Chinese Medicine,2024,37(12):120-123.[doi:10.12174/j.issn.2096-9600.2024.12.28]
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肠道微生物诱导胆囊结石形成机制的研究进展
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年12期
页码:
120-123
栏目:
研究进展
出版日期:
2024-12-15

文章信息/Info

Title:
Research Progress of the Mechanism of Gallbladder Calculus Formation Induced by Gut Microorganisms
作者:
潘浩宇1, 刘志春2, 张春花2, 王定新3
1.甘肃中医药大学第一临床医学院，甘肃 兰州 730000
2.天水市第一人民医院，甘肃 天水 741000
3.天水市卫生健康委员会，甘肃 天水 741000
Author(s):
PAN Haoyu1, LIU Zhichun2, ZHANG Chunhua2, WANG Dingxin3
1.First Clinical Medical College, Gansu University of Chinese Medicine, Lanzhou 730000, China
2.Tianshui City First People's Hospital, Tianshui 741000, China
3.Tianshui City Health Commission, Tianshui 741000, China
关键词:
胆囊结石; 肠道微生物; 胆汁酸; 湿热证; 机制
Keywords:
gallbladder calculus; gut microorganisms; bile acid; damp-heat pattern; the mechanism
分类号:
R256.4
DOI:
10.12174/j.issn.2096-9600.2024.12.28
文献标志码:
A
摘要:
研究证实肠道微生物通过多种途径参与胆囊结石的发生、发展，湿热证是胆囊结石的中医病机，而肠道微生物与湿热证相互作用，相互影响。文章从肠道微生物及其代谢产物通过调控胆汁酸代谢及中医湿热内蕴引起肠道微生物失衡而诱发胆囊结石等方面阐述肠道微生物引起胆囊结石的发生机制，并指出调整肠道微生物及其代谢产物可能是预防和治疗胆囊结石的新的治疗方向。
Abstract:
More and more research has confirmed that gut microorganisms are involved in the occurrence and development of gallbladder stones, interacting with the damp-heat pattern, as damp-heat pattern is the pathogenesis of gallbladder stones in TCM. The mechanism of gallbladder stone formation induced by intestinal microorganisms was elaborated from the aspects that intestinal microorganisms and their metabolites regulate the metabolism of bile acids, and the imbalance of intestinal microorganisms caused by the internal accumulation of damp-heat, thereby inducing gallbladder stones, meanwhile, the regulation of intestinal microorganisms and their metabolites might be the new therapeutic direction for the prevention and treatment of gallbladder calculus.

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备注/Memo

备注/Memo:
潘浩宇（1999—），男，在读硕士研究生，医师。研究方向：普外科疾病的中西医结合治疗。甘肃省天水市科技局科技支撑计划基金资助项目（2023-SHFZKJK-3564）。
更新日期/Last Update: 2024-12-15