[1]杨笑笑,董芳辉,余妹.中医护理对腹膜透析患者早发性腹膜炎发生情况的干预效果探讨[J].西部中医药,2025,38(03):131-134.[doi:10.12174/j.issn.2096-9600.2025.03.25]
　YANG Xiaoxiao,DONG Fanghui,YU Mei.Intervention Effects of TCM Nursing on the Incidence of Early-onset Peritonitis in Patients Undergoing Peritoneal Dialysis[J].Western Journal of Traditional Chinese Medicine,2025,38(03):131-134.[doi:10.12174/j.issn.2096-9600.2025.03.25]
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中医护理对腹膜透析患者早发性腹膜炎发生情况的干预效果探讨()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年03期
页码:
131-134
栏目:
临床研究
出版日期:
2025-03-15

文章信息/Info

Title:
Intervention Effects of TCM Nursing on the Incidence of Early-onset Peritonitis in Patients Undergoing Peritoneal Dialysis
作者:
杨笑笑, 董芳辉, 余妹
上海市第六人民医院，上海 201306
Author(s):
YANG Xiaoxiao, DONG Fanghui, YU Mei
The 6th People’s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 201306, China
关键词:
早发性腹膜炎; 腹膜透析; 中医护理; 炎症因子
Keywords:
early-onset peritonitis; peritoneal dialysis; TCM nursing; inflammatory factors
分类号:
R248
DOI:
10.12174/j.issn.2096-9600.2025.03.25
文献标志码:
B
摘要:
目的观察中医护理对腹膜透析（peritoneal dialysis，PD）患者早发性腹膜炎（early-onset peritonitis，EOP）发生情况的干预效果。 方法将96例PD患者，根据随机原则分为对照组和观察组，每组48例。对照组采用PD专科护理干预，观察组在对照组基础上联合中医辨证护理干预。比较两组患者在院时、出院1个月、出院3个月和出院6个月时腹膜炎发生情况以及腹膜炎发生次数，比较干预前后患者白细胞计数、中性粒细胞与淋巴细胞的比值（neutrophils-lymphocytes ratio，NLR）、血小板与淋巴细胞的比值（platelets-lymphocytes ratio，PLR）、血清白细胞介素1β（interleukin-1β，IL-1β）、IL-6、IL-10和肿瘤坏死因子α（tumor necrosis factor-α，TNF-α）表达水平；评估患者对中医护理的依从性，分析中医护理依从性与EOP发生率的相关性。 结果观察组在院时和出院1个月时均无EOP发生，对照组同期各发生4例EOP，差异有统计学意义（P＜0.05）；观察组出院3个月和出院6个月时有2名患者出现EOP，对照组同期各有7名患者出现EOP，差异有统计学意义（P＜0.05）；两组发生腹膜炎的患者腹膜炎发生次数均为1次，无反复发作情况；干预后，观察组白细胞计数、NLR、PLR及血清IL-1β、IL-6、IL-10和TNF-α表达水平均升高，但对照组升高更明显，差异有统计学意义（P＜0.05）；中医护理依从性与EOP发生率具有显著相关性，其敏感性约92.3%，特异性约95.2%（AUC0.990）。 结论在常规护理基础上对PD患者实施中医护理，能够降低PD相关性EOP的发生率和发生次数，降低血清炎症因子表达水平，从而改善患者预后和生活质量。
Abstract:
ObjectiveTo observe the intervention effects of TCM nursing on the incidence of early-onset peritonitis (EOP) in patients undergoing peritoneal dialysis (PD). MethodsAll 96 PD patients were allocated to the control group and the observation group according to randomization principle with 48 cases in each group. The control group adopted PD specialist nursing intervention, and the observation group accepted nursing intervention of TCM syndrome differentiation based on the care of the control group. To compare the incidence and the times of EOP between the two groups when hospitalized, one month after discharging, three and six months after the discharging, and to detect WBC count, NLR, PLR and the expressions of IL-1β, IL-6, IL-10 and TNF-α before and after the intervention; to assess the patients’ compliance with TCM care, and to analyze the correlation between TCM nursing compliance and EOP incidence. ResultsThere was no EOP in the observation group when the patients were hospitalized and one month after the discharging, while four cases of EOP occurred in the control group in the corresponding period, and the difference had statistical meaning (P<0.05); Two patients suffered EOP in the observation group three months and six months after discharging, while seven manifested EOP in the control group over the same period, and the difference was statistically significant (P<0.05); the patients in the two groups suffered EOP only once, and there was no recurrence; after the intervention, WBC count, NLR, PLR, the expressions of IL-1β, IL-6, IL-10 and TNF-α were increased in the observation group, while the increase of the control group was more evident, and the difference had statistical meaning (P<0.05); there was a significant correlation between TCM nursing compliance and the incidence of EOP, with a sensitivity of around 92.3%, and the specificity of 95.2% (AUC0.990). ConclusionOn the foundation of conventional nursing, TCM nursing given to PD patients could reduce the incidence and the times of PD-related EOP, lower the expressions of serum inflammatory factors, thereby improving the patients’ prognosis and quality of life.

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备注/Memo

备注/Memo:
杨笑笑（1981—），女，主管护师。研究方向：肾脏疾病的临床护理。Email：330331269@qq.com。上海市中医药科研基金项目（2020Q104）。
更新日期/Last Update: 2025-03-15