[1]朱慧霞,王丽亚.除湿汤加味对小儿厌食症脾胃湿热证患儿疗效及血清胃肠激素水平的影响[J].西部中医药,2026,39(04):96-98.[doi:10.12174/j.issn.2096-9600.2026.04.20]
　ZHU Huixia,WANG Liya.Clinical Effects of Modified Dampness-eliminating Decoction in the Treatment of Pediatric Anorexia with Damp-heat in the Spleen and Stomach and Its Influence on the Levels of Gastrointestinal Hormones[J].Western Journal of Traditional Chinese Medicine,2026,39(04):96-98.[doi:10.12174/j.issn.2096-9600.2026.04.20]
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除湿汤加味对小儿厌食症脾胃湿热证患儿疗效及血清胃肠激素水平的影响()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年04期
页码:
96-98
栏目:
临床研究
出版日期:
2026-04-15

文章信息/Info

Title:
Clinical Effects of Modified Dampness-eliminating Decoction in the Treatment of Pediatric Anorexia with Damp-heat in the Spleen and Stomach and Its Influence on the Levels of Gastrointestinal Hormones
作者:
朱慧霞, 王丽亚
南京中医药大学附属张家港医院，江苏 张家港 215600
Author(s):
ZHU Huixia, WANG Liya
Zhangjiagang Hospital Affiliated to Nanjing University of Chinese Medicine, Zhangjiagang 215600, China
关键词:
厌食症; 脾胃湿热证; 除湿汤; 胃动素; 胃泌素
Keywords:
anorexia; damp-heat in the spleen and stomach; dampness-eliminating decoction; motilin; gastrin
分类号:
R256.39
DOI:
10.12174/j.issn.2096-9600.2026.04.20
文献标志码:
B
摘要:
目的探讨除湿汤加味对小儿厌食症脾胃湿热证的疗效及血清胃肠激素水平的影响。 方法选取146例小儿厌食症脾胃湿热证患儿作为研究对象，采用随机数字表法分为观察组和对照组，每组73例。对照组给予胃蛋白酶口服液口服干预，观察组在对照组治疗基础上服用除湿汤加味治疗。两组均连续治疗8周，并随访观察。比较两组临床疗效、日摄食量、脾胃湿热证证候评分及血清胃肠激素水平。 结果观察组总有效率［97.26％（71/73）］高于对照组［84.93％（62/73）］（P＜0.05）。治疗4、8周后，两组患儿日摄食量、血清胃动素及胃泌素水平均较治疗前升高（P＜0.05），脾胃湿热证证候评分均较治疗前降低（P＜0.05）；且观察组上述指标改善程度均优于对照组，差异有统计学意义（P＜0.05）。 结论除湿汤加味治疗小儿厌食症脾胃湿热证患儿疗效显著，可增加患儿日摄食量，改善中医证候，调节血清胃肠激素水平。
Abstract:
ObjectiveTo analyze therapeutic effects of modified dampness-eliminating decoction in the treatment of pediatric anorexia with damp-heat in the spleen and stomach and its influence on the levels of gastrointestinal hormones. MethodsA total of 146 children with anorexia of the spleen-stomach damp-heat syndrome were selected as the study subjects and randomly divided into an observation group and a control group using a random number table, with 73 cases in each group. The control group was treated with oral pepsin oral solution, while the observation group was treated with modified dampness-eliminating decoction in addition to the treatment given to the control group. Both groups were treated continuously for eight weeks and followed up. The clinical efficacy, daily food intake, spleen-stomach damp-heat syndrome scores, and serum gastrointestinal hormone levels were compared between the two groups. ResultsThe total effective rate of the observation group [97.26% (71/73)] was higher than that of the control group [84.93% (62/73)] (P<0.05). After four and eight weeks of treatment, the daily food intake, serum motilin and gastrin levels in both groups were increased compared with those before treatment (P<0.05), while the spleen-stomach damp-heat syndrome scores were decreased compared with those before treatment (P<0.05). Moreover, the improvement in the above indicators in the observation group was superior to that in the control group, and the differences were statistically significant (P<0.05). ConclusionModified dampness-eliminating decoction is highly effective in treating pediatric anorexia with damp-heat in the spleen and stomach, as evidenced by increased daily food intake, alleviated TCM syndromes, and regulated serum gastrointestinal hormone levels.

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备注/Memo

备注/Memo:
江苏省自然科学基金面上项目（BK20221381）。朱慧霞（1987—），女，主治中医师。研究方向：儿童消化系统疾病的中医药诊治。
更新日期/Last Update: 2026-04-15