[1]梁 周,王大伟△,陆兰兰,等.通脉生骨Ⅱ号方对激素性股骨头缺血性坏死BGP及VEGF表达的影响*[J].西部中医药,2012,25(10):44-46.
　LIANG Zhou,WANG Da-wei,LU Lan-lan,et al.Influence of TongMai ShengGu Recipe II on Expressions of BGP and VEGF in Glucocorticoid-induced Avascular Necrosis of Femoral Head[J].Western Journal of Traditional Chinese Medicine,2012,25(10):44-46.
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通脉生骨Ⅱ号方对激素性股骨头缺血性坏死BGP及VEGF表达的影响*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
25
期数:
2012年10期
页码:
44-46
栏目:
出版日期:
2012-10-15

文章信息/Info

Title:
Influence of TongMai ShengGu Recipe II on Expressions of BGP and VEGF in Glucocorticoid-induced Avascular Necrosis of Femoral Head
文章编号:
1004-6852(2012)10-0044-03
作者:
梁 周1，王大伟2△，陆兰兰1，龙朝阳1，陈双辉1，陈明科1
1 广西中医药大学，广西 南宁 530001； 2 广西中医药大学附属瑞康医院骨科
Author(s):
LIANG Zhou1, WANG Da-wei2△, LU Lan-lan1, LONG Zhao-yang1, CHEN Shuang-hui1, CHEN Ming-ke1
1 Guangxi University of Chinese Medicine, Nanning 530001, China；2 Ruikang Hospital of Guangxi Traditional Chinese Medical University
关键词:
股骨头坏死; 激素性; 通脉生骨Ⅱ号方; BGP; VEGF; 实验研究
Keywords:
necrosis of femoral head;  glucocorticoid-induced;  TongMai ShengGu recipe II;  BGP;  VEGF;  experimental study
分类号:
R683.421
文献标志码:
A
摘要:
目的：探讨中药通脉生骨Ⅱ号方对实验性兔BGP及VEGF表达的影响。方法：将45只健康成年雄性新西兰大白兔随机分成空白组，模型组，对照组，汤剂组4组，观察治疗前后BGP及VEGF的表达。结果：各组BGP及VEGF值治疗前后有显著性差异。结论：通脉生骨Ⅱ号方对家兔激素性股骨头坏死预防、治疗作用方面优于盐酸川芎嗪碱，有显著的防治效果。
Abstract:
Objective: To approach the influence of TongMai ShengGu recipe II on BGP and VEGF in experimental rabbits. Method: Forty-five healthy rabbits were randomly divided into blank group, model group, control group and decoction group, to observe expressions of BGP and VEGF before and after treating. Result: There are remarkable differences before and after treating in BGP and VEGF among different groups. Conclusion: TongMai ShengGu recipe II is better than ligustrazine in preventing and treating glucocorticoid-induced necrosis of femoral head, showing remarkable preventive effect.

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备注/Memo

备注/Memo:
收稿日期：2012-03-26 *基金项目：2010年广西研究生教育创新计划资助项目(编号2010106001006M26) 作者简介：梁周(1981—)，男，硕士研究生。研究方向：骨与关节退变与缺血性疾病的防治。 △通讯作者：王大伟(1956—)，男，硕士研究生导师，主任医师，教授。研究方向：骨与关节退变及缺血性疾病的防治。
更新日期/Last Update: 1900-01-01