[1]侯俊明,王磊.莪黄汤联合化疗治疗直肠癌前切除术后综合征疗效观察[J].西部中医药,2012,25(11):85-87.
 HOU Jun-ming,WANG Lei.Observation on Effects of EHuangTang and Chemotherapy on Anterior Resection Syndrome of Rectal Cancer[J].Western Journal of Traditional Chinese Medicine,2012,25(11):85-87.
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莪黄汤联合化疗治疗直肠癌前切除术后综合征疗效观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
25
期数:
2012年11期
页码:
85-87
栏目:
出版日期:
2012-11-15

文章信息/Info

Title:
Observation on Effects of EHuangTang and Chemotherapy on Anterior Resection Syndrome of Rectal Cancer
文章编号:
1004-6852(2012)11-0085-03
作者:
侯俊明1王磊2
1 陕西中医学院第一附属医院,陕西 咸阳 712000;2 陕西中医学院
Author(s):
HOU Jun-ming1, WANG Lei2
1 A ffiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, China; 2 Shaanxi University of Chinese Medicine
关键词:
直肠癌前切除术后综合征莪黄汤生活质量
Keywords:
rectal cancer anterior resection syndrome EHuangTang life quality
分类号:
R273
文献标志码:
B
摘要:
目的:观察莪黄汤联合化疗对直肠癌保肛术患者前切除术后排便功能及生活质量的影响。方法:将 40例直肠癌术后患者随机分为治疗组 22 例和对照组 18 例,2 组均采用 FOLFOX4 方案化疗,治疗组加用莪黄汤保留灌肠治疗,疗程为 4 周。治疗 4 周后,观察 2 组排便功能以及生活质量变化情况。结果:排便次数、大便失禁频次评分、大便能否在 15 分钟内排完、是否存在不能完全排净的感觉治疗组治疗前后比较差异有统 计学意义(P<0.01 或 P<0.05),2 组治疗后组间比较差异有统计学意义(P<0.01);排便次数、大便失禁频次评分对照组治疗前后比较差异有统计学意义(P<0.01 或 P<0.05),而大便能否在 15 分钟内排完、不能完全排净的感觉对照组治疗前后比较差异无统计学意义(P>0.05)。治疗组生活质量改善例数明显高于对照组(P<0.05)。结论:莪黄汤可有效改善前切除术后患者排便功能,能提高患者生活质量,值得临床推广及进一步研究。
Abstract:
Objective: To explore the effects of EHuangTang and chemotherapy on life quality and defecationfunction in patients with anterior resection syndrome of rectal cancer. Method: Forty cases were randomly divided into 22 cases in treatment group and 18 cases in control group. Both groups received FOLFOX4 plan of chemotherapy, treatment group were also treated with retention enema of EHuangTang, four weeks were one course.The effects on defecation function and life quality of both groups were observed. Result: Comparison of treatment group between before and after treating showed statistical meaning in defecation times, score of fecal incontinence frequency, whether defecation can finish within 15 minutes, the sense of incomplete defecation(P< 0.01 or P< 0.05),comparison between both groups after treating demonstrated statistical meaning (P< 0.01); comparisons of control group between before and after treating demonstrated statistical meaning in defection times and frequency scale of fecal incontinence (P< 0.01 or P< 0.05), while comparison of control group between before and after treating had no statistical meaning in whether defecation can finish within 15 minutes, the sense of incomplete defecation (P>0.05).The improved cases of treatment group were higher than control group obviously in life quality (P < 0.05).Conclusion: EHuangTang can effectively improve defecation of patients with anterior resection and raise life qualityof patients.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2012-04-27 作者简介:侯俊明(1964—),男,硕士研究生导师,教授,主任医师。研究方向:腺体、消化道肿瘤的基础与临床研究。
更新日期/Last Update: 2012-11-15