[1]骆元斌,顾立萍,黄小玲△.胃黄色瘤30例临床病理分析[J].西部中医药,2013,26(01):119.
 LUO Yuanbin,GU Liping,HUANG Xiaoling.Pathological Analysis for 30 Cases of Gastric Xanthoma[J].Western Journal of Traditional Chinese Medicine,2013,26(01):119.
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胃黄色瘤30例临床病理分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年01期
页码:
119
栏目:
出版日期:
2013-01-15

文章信息/Info

Title:
Pathological Analysis for 30 Cases of Gastric Xanthoma
文章编号:
1004-6852(2013)01-0119-02
作者:
骆元斌1顾立萍2黄小玲1△
1 甘肃省中医院病理科,甘肃 兰州 730050;
2 甘肃省中医药研究院
Author(s):
LUO Yuanbin1, GU Liping2, HUANG Xiaoling1△
1 Department of Pathology in Gansu Province Hospital of Traditional Chinese Medicine, Lanzhou 730050, China;
2 Gansu Province A cademy of Chinese Medicine
关键词:
胃黄色瘤慢性胃炎幽门螺杆菌
Keywords:
gastric xanthoma chronic gastritis helicobacter pylori (Hp)
分类号:
R36
文献标志码:
B
摘要:
目的:探讨胃黄色瘤(脂质岛)的临床病理特征及其与胃黏膜病变的关系。方法:收集2007—2012年胃黏膜活检资料,并对胃镜活检病理诊断为胃黄色瘤的30例病例进行病理分析。结果:3293例胃黏膜活检患者中胃黄色瘤检出30例,检出率为0.9%,病变位于胃窦部20例(66.7%);伴发浅表性胃炎2例(6.7%),萎缩性胃炎者28例(93.3%),伴发肠上皮化生者7例(23.3%),幽门螺杆菌阳性者4例(13.3%),非典型增生者5例(16.7%)。结论:胃黄色瘤好发于老年人,可能是年龄增长、慢性炎症刺激、萎缩、原发或继发性血脂过高、幽门螺杆菌感染等多种因素协同作用的结果,其中胃黏膜的炎症可能起主要作用。
Abstract:
Objective: To explore pathological features of gastric xanthoma (lipid island) and the relationship between gastric xanthoma and gastric mucosal lesion. Method: The date of gastric mucosal biopsy from 2007 to 2012 was collected and 30 cases of gastric xanthoma were analyzed pathologically. Result: All 30 cases were detected with gastric xanthoma from 3 293 patients,the detection rate of gastric xanthoma was 0.9% in gastriscope biopsy.Among 30 cases, there were 20 cases of lesions located at gastric antrium (66.7%); two cases complicated with superficial gastritis (6.7%), 28 cases of atrophic gastritis (93.3%), seven cases complicated with intestinal metaplasia (23.3%), four cases with negative helicobacter pylori (Hp) (13.3%), and five cases of atypical hyperplasia(16.7%).Conclusion: Gastric xanthoma usually happens in the elderly and it might be the result of age, chronic inflammation irritation, atrophy, primary and secondary hyperlipoidemia, Hp infection working together, the inflammation of gastric mucosa plays the key role among them.

参考文献/References:

[1] 刘先琪,冯丹书,候景贵,等.胃的黄色瘤 45 例临床分析[J].中华消化杂志,1997(9):97.
[2] Petrov S,Churtchev J,Mitova R,et al.Xanthoma of the stomach-some morphometrical peculiarities and scanning electron microscopy[J].Hepatogastroenterology,1999,46(26):1220-1222.
[3] Werzler G,Felix AA,Lipton JF,et al.Gastric xanthelasma[J].J Pediatr Gastroenterol Nutr,2010,51(1):1.
[4] 崔荣丽,金珠.胃黄色瘤的临床病理分析 312 例[J].世界华人消化杂志,2007,15(6):646-648.
[5] Halabi I,Yaseen M,Vesoulis Z.Multiple gastric xanthomas in a 3-year-old patient[J].Gastroenterol Hepatol(NY),2010,6(3):181-183.
[6] Gürsoy S,Yurci A,Torun E,et al.An uncommon lesion:gastric xanthelasma[J].Turk J Gastroenterol,2005,16(3):167-170.
[7] Naito M,Miura S,Funaki C,et al.Gastric xanthomas in the elderly[J].Nippon Roen I gakai Zasshi,1991,28:683-687.
[8] Arevalo F,Cerrillo G.Gastric xanthoma:histological findings and clinic endoscopic characteristics in the"Hospital Nacional 2 de Mayo" (1999—2005)[J].RevGastroenterol Peru,2005,25(3):268-271.
[9] Muraoka A,Suehiro I,Fujii M,et al.Type II early gastric cancer with proliferation of xanthoma cells [J].J Gastroenterol,1998,33(3):326-329.
[10] Kaiserling E,Heinle H,Itabe H,et al.Lipid islands in human gastric mucosa: Morphological and immunohistochemical findings [J].Gastroenterology,1996,110(2):369-374.
[11]Isomoto H,Mizuta Y,Inoue K,et al.A close relationship between helicobacter pylori infection and gastric xanthomas[J].Scand J Gastroenterol,1999,34(4):346-352.

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备注/Memo

备注/Memo:
收稿日期:2012-09-20
作者简介:骆元斌(1977—),男,硕士学位,主治医师。研究方向:消化道、骨及软组织病理诊断。
△通讯作者:黄小玲(1962—),女,主任医师,教授,中华医学会病理学会会员,中国抗癌协会甘肃省肉瘤专业委员会委员,中国医师协会专科会员,甘肃省医学会医疗事故技术鉴定专家库成员,兰州市医学会医疗事故技术鉴定专家库成员。研究方向:骨及软组织肿瘤。
更新日期/Last Update: 1900-01-01