[1]张桂华,苏红宝,赵健.鳖甲软肝胶囊联合拉米夫定、阿德福韦酯片治疗失代偿期乙肝肝硬化临床观察[J].西部中医药,2013,26(02):1-4.
　ZHANG Guihua,SU Hongbao,ZHAO Jian.Clinical Observation on BieJia RuanGan Capsule Combined with Lamivudine, Adefovir Dipivoxil Tablets for Decompensated Cirrhosis of Hepatitis B[J].Western Journal of Traditional Chinese Medicine,2013,26(02):1-4.
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鳖甲软肝胶囊联合拉米夫定、阿德福韦酯片治疗失代偿期乙肝肝硬化临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年02期
页码:
1-4
栏目:
出版日期:
2013-02-15

文章信息/Info

Title:
Clinical Observation on BieJia RuanGan Capsule Combined with Lamivudine, Adefovir Dipivoxil Tablets for Decompensated Cirrhosis of Hepatitis B
文章编号:
1004-6852(2013)02-0001-04
作者:
张桂华1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，苏红宝1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2，赵健1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2
1 太和县中医院，安徽 太和 236600；2 全国重点肝病专科
Author(s):
ZHANG Guihua1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2, SU Hongbao1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2, ZHAO Jian1,2' target="_blank" rel="external">2' target="_blank" rel="external">2' target="_blank" rel="external">2
1 Taihe County TCM Hospital, Taihe 236600, China; 2 National Key Department of Hepatology
关键词:
失代偿期肝硬化; 鳖甲软肝胶囊; 拉米夫定; 阿德福韦酯片
Keywords:
discompensated cirrhosis;  BieJia RuanGan capsule;  lamivudine;  adefovir dipivoxil tablets
分类号:
R969
文献标志码:
A
摘要:
目的：探讨鳖甲软肝胶囊联合拉米夫定、阿德福韦酯治疗乙肝失代偿期肝硬化的临床疗效。方法：收集乙肝肝硬化同时符合抗病毒适应症且中医辨证为湿热瘀毒，肝脾血瘀证的患者82例，随机分为2组。治疗组46例给予鳖甲软肝胶囊、拉米夫定、阿德福韦酯治疗;对照组36例给予拉米夫定和阿德福韦酯及保肝治疗，疗程72周。结果：在降低证侯积分，改善肝功能、肝纤维化指标、肝门脉压力及HBVDNA阴转等方面2组比较有统计学意义，治疗组优于对照组（P＜0.05）。结论：鳖甲软肝胶囊联合拉米夫定阿德福韦酯治疗失代偿期乙肝肝硬化疗效明显。
Abstract:
Objective: To explore clinical effects of BieJia RuanGan capsule combined with lamivudine,adefovir dipivoxil tablets in treating decompensated cirrhosis of hepatitis B. Method: Eighty-two patients, proved with cirrhosis of hepatitis B and up to antiviral indications, were differentiated with the patterns of dampness-heat-stagnation-toxicity andblood stasis of liver and spleen, collected, divided into both groups. 46 cases in the treatment group took BieJia RuanGan capsule, lamivudine and adefovir dipivoxil tablets. 36 cases in the control group received lamivudine, adefovir dipivoxil tablets and protecting liver therapy. The course of treatment was 72 weeks. Result: Comparisons of both groups demonstrated statistical meaning in decreasing symptom scale,improving liver function, indexes of liver fibrosis, pressure of hepatic portal vein, negative conversion of HBV-DNA, the treatment group was superior to the control group (P＜0.05). Conclusion: BieJia RuanGan capsule combined with lamivudine, adefovir dipivoxil tablets are effective in treating discompensated cirrhosis of hepatitis B.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期：2012-09-06 作者简介：张桂华(1967—)，男，副主任医师。研究方向：慢性乙型肝炎的中西医结合治疗及中医复方抗肝纤维化研究。
更新日期/Last Update: 2013-02-15