[1]马乔娟.银杏叶提取物对绝经后冠心病妇女冠脉血流及血管弹性的影响[J].西部中医药,2013,26(02):24-26.
 MA Qiaojuan.Effects of Ginaton on Coronary Blood Flow and Vascular Elasticity of Postmenopausal Women with Coronary Heart Disease[J].Western Journal of Traditional Chinese Medicine,2013,26(02):24-26.
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银杏叶提取物对绝经后冠心病妇女冠脉血流及血管弹性的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年02期
页码:
24-26
栏目:
方药·药理研究
出版日期:
2013-02-15

文章信息/Info

Title:
Effects of Ginaton on Coronary Blood Flow and Vascular Elasticity of Postmenopausal Women with Coronary Heart Disease
文章编号:
1004-6852(2013)02-0024-03
作者:
马乔娟
陕西煤化集团铜川矿务局中心医院心内科,陕西 铜川 727000
Author(s):
MA Qiaojuan
Department of Cardiology in Central Hospital of Tongchuan Coal Mining Bureauin Shaanxi Coal and Chemical Industry Group Co., Ltd., Tongchuan 727000, China
关键词:
冠心病绝经银杏叶提取物冠脉血流血管弹性
Keywords:
coronary heart disease menopause ginaton coronary blood flow vascular elasticity
分类号:
R541.4
文献标志码:
A
摘要:
目的:探讨银杏叶提取物对绝经后冠心病妇女冠脉血流及血管弹性的影响。方法:将92例绝经后冠心病患者随机分为2组,常规西医治疗组(对照组)46例,银杏叶提取物治疗组(观察组)46例,观察组在常规西医治疗的基础上深部肌肉注射银杏叶提取物注射液,治疗14天后观察血液黏度、冠脉血流以及影响血管弹性功能的各因子变化情况。结果:治疗后观察组全血黏度以及高切黏度、低切黏度均显著低于对照组(P<0.05);治疗后观察组一氧化氮和内皮素水平显著高于对照组(P<0.05),而前列环素则显著低于对照组(P<0.05);治疗后观察组舒张期峰值和收缩期峰值速度均显著快于对照组(P<0.05)。结论:银杏叶提取物能有效降低绝经后冠心病妇女冠脉粥样硬化程度,提高其冠脉血流速度,增加血管弹性,对提高疗效有积极作用。
Abstract:
Objective: To explore the effects of ginaton on coronary blood flow and vascular elasticity of postmenopausal women with coronary heart disease. Method: Ninety-two patients were randomly divided into the treatment group of routine western medicine treatment (the control group) and the treatment group of ginaton (the observation group) equally. The observation group received deep intramuscular injection of ginaton injection, blood viscosity, coronary blood flow and internal factors influencing vascular elasticity were observed after treating for 14 days. Result: The observation group were lower than the control group after treating in whole blood viscosity, high and low shear viscosity (P<0.05); the observation group were higher than the control group in nitric oxide and en-dothelin significantly (P<0.05); lower than control group in prostacyclin (P<0.05); peak value of diastole and peakvelocity of systole in the observation group were faster than that of the control group after treating (P<0.05). Conclusion: Ginaton could effectively decrease the degree of coronary atherosclerosis, raise coronary blood flow velocity and increase vascular elasticity of postmenopausal women with coronary heart disease, which performs an active role in improving the effects.

参考文献/References:

[1] 武宇洲,杨国锋,刘润田,等.银杏叶提取物治疗老年冠心病心绞痛临床观察[J].辽宁中医药杂志,2008,35(10):1515-1516. [2] Shim SH,Kim JM,Choi CY.Ginkgo biloba extract and bilberry anthocyanins improve visual function in patients with normal tension glaucoma[J].J Med Food,2012,15(9):818-823. [3] 武宇洲,杨国锋,刘润田,等.银杏叶提取物注射液治疗绝经后女性冠心病的临床观察[J].时珍国医国药,2009,20(4):946-947. [4] 刘颖.银杏叶制剂的药理作用及临床研究概述[J].中医药信息,2011,28(4):145-146. [5] 郭美华,张新建,段丽娟,等.银杏叶有效成分的提取工艺[J].中医药信息,2010,27(5):18-20. [6] Zhang SJ,Xue ZY.Effect of western medicine therapy assisted by Ginkgo biloba tablet on vascular cognitive impairment of none dementia[J].Asian Pac J Trop Med,2012,5(8):661-664. [7] Lautenschlager NT,Ihl R,Müller WE.Ginkgo biloba extract EGb 761 in the context of current developments in the diagnosis and treatment of age-related cognitive decline and alzheimer's disease:a research perspective[J].Int Psychogeriatr,2012,24(1):46-50. [8] 李淑琴,武字洲,祖秀光.银杏叶提取物对老年冠心病患者冠脉血流和内皮功能的影响[J].北京中医药大学学报,2008,31(10):712-714. [9] 谭红英.中药治疗反复发作口腔溃疡 13 例观察[J].实用中医内科杂志,2006,20(5):541. [10]王桂英,高英梅,郝玉杰,等.银杏叶提取物药理作用的研究进展[J].河北中医,2009,31(6):944-946.

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备注/Memo

备注/Memo:
收稿日期:2012-10-25 作者简介:马乔娟(1976—),女,主治医师。研究方向:冠心病、心衰、高血压等疾病的诊治。
更新日期/Last Update: 2013-02-15