云南白药联合LEEP治疗宫颈上皮内瘤变60例-《西部中医药》

文章信息/Info

Title:: YunNan BaiYao and LEEP in Treating 60 Cases of Cervical Intraepithelial Neoplasia

Author(s):: WANG Liying1，WANG Liping2; 1 Department of Gynecology and Obstetrics in Handan County Hospital, Handan 056000, China； 2 Shexian County Hospital

摘要:: 目的：观察云南白药联合LEEP治疗宫颈上皮内瘤变(CIN)的临床疗效。方法：将120例CIN患者随机分为2组。2组患者均行LEEP治疗。观察组用4 g云南白药粉倒入宫颈处，再用无菌纱布填塞宫颈处起压迫止血作用。2组术后均常规给予抗生素治疗。结果：术后出血量观察组平均(17.2±4.5)mL，对照组平均(24.5±5.6)mL，2组相比差异有统计学意义(P＜0.05)；术后脱痂期阴道流血过多观察组2例(3.33％)，对照组8例(13.33%)，2组相比差异有统计学意义(P＜0.05)；宫颈塑形满意观察组58例(96.67％)，对照组52例(86.67%)，2组相比差异有统计学意义(P＜0.05)；宫颈创面完全修复时间观察组平均(35.5±4.4)天，对照组平均(48.2±5.6)天；阴道排液时间观察组平均(7.3±0.5)天，对照组平均(12.5±0.8)天；宫颈创面完全修复时间、阴道排液时间2组比较差异有统计学意义（P＜0.05)。结论：云南白药联合LEEP治疗CIN临床疗效显著。

Abstract:: Objective: To observe clinical effects of YunNan BaiYao and LEEP in treating cervical intraepithelial neoplasia(CIN). Method: All 120 patients were randomized into two groups. Both groups were treated with LEEP. The observation group were poured YunNan BaiYao, 4 g, to the cervix, filled with sterile gauze and pressed to stop the bleeding. Both groups were adiministered with antibiotics. Result: Average bleeding amount of the observation group was (17.2±4.5) mL and the control group (24.5±5.6)mL, the difference had statistical meaning (P＜0.05). In the stadium of decrustation, there were two cases (3.33%) with more vaginal bleeding after surgery in the observation group and eight cases in the control group (13.33%), the difference had statistical meaning (P＜0.05).There were 58 patients satisfied with cervical regeneration in the observation group (96.67%) and 52 cases in the control group (86.67%), the difference had statistical meaning (P＜0.05). Average time of cervical wound complete recovery in the observation group was (35.5±4.4) days and the control group (48.2±5.6) days; average vaginal discharging time in the observation group was (7.3±0.5) days and the control group(12.5±0.8) days. The difference had statistical meaning in complete recovery time of cervical wound and vaginal discharging time(P＜0.05). Conclusion: YunNan BaiYao and LEEP could obtain notable effects in treating CIN.