[1]胡君茹,姜 华,李喜香.三种非水溶性供试品溶剂对抑菌试验效果的影响[J].西部中医药,2013,26(11):30-31.
 HU Junru,JIANG Hua,LI Xixiang.Study on Three Non-water-soluble Solvents Influencing of Inhibitory Activity in Antibacterial Test[J].Western Journal of Traditional Chinese Medicine,2013,26(11):30-31.
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三种非水溶性供试品溶剂对抑菌试验效果的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年11期
页码:
30-31
栏目:
出版日期:
2013-11-15

文章信息/Info

Title:
Study on Three Non-water-soluble Solvents Influencing of Inhibitory Activity in Antibacterial Test
文章编号:
1004-6852(2013)11-0030-02
作者:
胡君茹1姜 华1李喜香2
1 甘肃省中医药研究院,甘肃 兰州 730050; 2 甘肃省中医院
Author(s):
HU Junru1, JIANG Hua1, LI Xixiang2
1 Gansu Provincial Academy of Chinese Medicine, Lanzhou 730050, China; 2 Gansu Provincial Hospital of Traditional Chinese Medicine
关键词:
吐温-80DMSO12-丙二醇非水溶性溶剂抑菌作用
Keywords:
tween-80 DMSO 1 2- propanediol non-water-soluble solvents inhibitory activity
分类号:
R927
文献标志码:
A
摘要:
目的:考察吐温-80、二甲基亚砜(DMSO)、1,2-丙二醇3种非水溶性物质溶剂,在抑菌试验中溶解非水溶性供试品时对抑菌效果的影响。方法:通过体外抑菌试验,用琼脂扩散法测定3种溶剂的抑菌作用。结果:DMSO与水混合的不同浓度对金黄色葡萄球菌和大肠杆菌均无抑菌作用,在抑菌试验中可用于溶解非水溶性供试品,而吐温-80和1,2-丙二醇对抑菌效果有干扰。结论:在考察非水溶性供试品的抑菌活性时,DMSO对抑菌结果无干扰,可作为适宜的溶剂溶解非水溶性供试品。
Abstract:
Objective: To survey the effects of tween-80, dimethyl sulfoxide (DMSO) and 1, 2- propanediol on inhibitory activity in antibacterial test. Method: Inhibitory activity of all the solvents was detected by agar disc diffusion method for antibacterial test in vitro. Result: Different concentrations of DMSO mixed liquid showed no inhibition to Staphylococcus aureus and Escherichia coli while Tween 80 and 1, 2-propanediol demonstrated interference to antibacterial results. Conclusion: In the investigation of inhibitory activity of non-water-soluble solvents, DMSO has no interference to antibacterial results and is suitable for dissolving non-water-soluble solvents in antibacterial test.

备注/Memo

备注/Memo:
收稿日期:2013-01-27 作者简介:胡君茹(1980—),女,主管药师。研究方向:医院药学与中药分析。
更新日期/Last Update: 2013-11-15