导赤散合清胃散化裁防治鼻咽癌放疗中鼻咽出血及口腔黏膜反应30例-《西部中医药》

文章信息/Info

Title:: Modified DaoChi San and QingWeiSan in Preventing 30 Cases of Nasopharyngeal Hemorrhage and Oral Mucosa Reactions Caused by Radiotherapy for Nasopharyngeal Carcinoma

Author(s):: LIAO Tianhua, HUANG Changjiang, CAI Kai, LIU Junbo, HU Lianmin, YU Zhaosheng, HUANG Lili; Guigang Municipal TCM Hospital, Guigang 537100, China

Keywords:: DaoChi San; QingWei San; nasopharyngeal carcinoma; nasopharyngeal hemorrhage; oral mucosa reaction

摘要:: 目的：观察导赤散合清胃散化裁治疗鼻咽癌放疗中鼻咽出血及口腔黏膜反应的临床疗效。方法：选择放疗中鼻咽癌患者60例，随机分为对照组和观察组各30例。对照组予以常规放疗，观察组在对照组的基础上使用导赤散、清胃散化裁水煎口服。观察放疗中患者鼻咽出血、口腔黏膜炎的发生率。结果：鼻咽出血发生率观察组为50.00%，对照组为73.33%，2组相比差异显著（P＜0.05）。口腔黏膜炎发病率观察组为70.0%，对照组为93.3%，2组相比差异显著（P＜0.05）。结论：导赤散合清胃散化裁可降低鼻咽癌放疗中鼻咽出血及口腔黏膜炎的发生率。

Abstract:: Objective: To explore clinical effects of modified DaoChi San and QingWei San in treating nasopharyngeal hemorrhage and oral mucosa reaction caused by radiotherapy for nasopharyngeal carcinoma. Methods: All 60 patients were randomized into the control group and the observation group. The control group were administered with radiotherapy and the observation group took modified DaoChi San and QingWeiSan on the foundation of the therapy given to the control group. The incidences of nasopharyngeal hemorrhage and oral mucosa reaction in the patients were observed. Results: The incidence of nasopharyngeal hemorrhage in the observation group was 50.00%, lower than 73.33% of the control group, the difference was significant (P＜0.05). The incidence of oral mucosa reaction in the control group was 93.3%, higher than 70.0% of the observation group, the difference was significant (P＜0.05). Conclusion: Modified DaoChi San and QingWei San could reduce the incidences of nasopharyngeal hemorrhage and oral mucosa reaction in the course of radiotherapy for nasopharyngeal carcinoma.