[1]倪树文,孙金蝉.乌梅丸对腹泻型肠易激综合征患者生活质量影响的随机对照研究[J].西部中医药,2014,27(03):7-10.
 NI Shuwen,SUN Jinchan.Influence of WuMei Pills on Life Quality of the Patients with Diarrhea-predominated Irritable Bowel Syndrome: A Report of Randomized Controlled Trial[J].Western Journal of Traditional Chinese Medicine,2014,27(03):7-10.
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乌梅丸对腹泻型肠易激综合征患者生活质量影响的随机对照研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年03期
页码:
7-10
栏目:
出版日期:
2014-03-15

文章信息/Info

Title:
Influence of WuMei Pills on Life Quality of the Patients with Diarrhea-predominated Irritable Bowel Syndrome: A Report of Randomized Controlled Trial
文章编号:
1004-6852(2014)03-0007-04
作者:
倪树文1孙金蝉2
1 华池县中医医院,甘肃 华池 745600; 2 华池县人民医院
Author(s):
NI Shuwen1, SUN Jinchan2
1 Huachi County TCM Hospital, Huachi 745600, China; 2 Huachi County People′s Hospital
关键词:
IBS-DIBS-QOL症状积分乌梅丸随机对照
Keywords:
IBS-D IBS-QOL symptom scale WuMei pills randomized controlled trial
分类号:
R259
文献标志码:
A
摘要:
目的:观察乌梅丸治疗腹泻型肠易激综合征(IBS-D)的临床疗效及生活质量的改善情况。方法:将90例符合纳入标准的IBS-D患者采用分层区组随机法随机分为试验组(乌梅丸组)、对照组(洛哌丁胺组)各45例。试验组予乌梅丸汤剂,1剂/d,分2次口服,对照组予洛哌丁胺4 mg,2次/d,口服。2组疗程均为4周,分别于治疗结束及3个月时随访,采用症状积分量表与肠易激综合征(IBS)患者专用生活质量表(IBS-QOL)进行症状评分。结果:乌梅丸与洛哌丁胺均能显著降低IBS-D患者的症状积分及IBS-QOL评分(P<0.01)。试验组总有效率达91.1%,明显优于洛哌丁胺的82.2%(P<0.05),且乌梅丸在改善症状积分与IBS-QOL评分方面均优于洛哌丁胺(P<0.05),在改善行为障碍、健康担忧、进食逃避、性行为及关系拓展方面的远期疗效优于洛哌丁胺(P<0.05)。结论:乌梅丸可从整体上有效改善IBS-D患者的生活质量,且无副作用。
Abstract:
Objective: To observe therapeutic effects of WuMei pills in treating diarrhea-predominated irritable bowel syndrome(IBS-D) and its influence on improving life quality of the patients. Methods: All 90 patients who met the included standards were randomly allocated into the trial group(WuMei pills group) and the control group (loperamide group) by layering randomized method. The trial group took the decoction of WuMei pills, one dose per day, taking the decoction twice, and the control group given with loperamide, 4 mg each time, twice per day, orally. Four weeks were one course of treatment, by the end of the treatment and the follow-ups in three months, the symptoms were assessed with symptom scale and IBS-QOL for the patients respectively. Results: WuMei pills and loperamide could significantly decrease symptom scale and IBS-QOL scale of the patients (P<0.01), total effective rate of the trial group could reach 91.1%, obviously better than 82.2% of loperamide group(P<0.05), and WuMei pills were superior to loperamide in improving symptom scale and IBS-QOL scales (P<0.05), in long-term effects of improving behavior disorder, health anxiety, eating escape, sexual behavior and relation expanding (P<0.05). Conclusion: WuMei pills could improve life quality of IBS-D patients totally, and it's safe.

备注/Memo

备注/Memo:
收稿日期:2013-07-06作者简介:倪树文(1972—),男,主治医师。研究方向:肠腑病的中医药防治。
更新日期/Last Update: 2014-03-15