[1]常荣天,尚德民,蒋嘉尧.麻黄附子细辛汤治疗急性呼吸窘迫综合征临床观察[J].西部中医药,2014,27(05):99-101.
　CHANG Rongtian,SHANG Demin,JIANG Jiayao.Curative Observation on MaHuang FuZi XiXin Decoction in Treating Acute Respiratory Distress Syndrome[J].Western Journal of Traditional Chinese Medicine,2014,27(05):99-101.
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麻黄附子细辛汤治疗急性呼吸窘迫综合征临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年05期
页码:
99-101
栏目:
出版日期:
2014-05-15

文章信息/Info

Title:
Curative Observation on MaHuang FuZi XiXin Decoction in Treating Acute Respiratory Distress Syndrome
文章编号:
1004-6852(2014)05-0099-03
作者:
常荣天，尚德民，蒋嘉尧
张掖市人民医院重症医学科，甘肃 张掖 734000
Author(s):
CHANG Rongtian, SHANG Demin, JIANG Jiayao
Department of Critical Care Medicine of Zhangye Municipality People′s Hospital, Zhangye 734000, China
关键词:
ARDS; 麻黄附子细辛汤; 治疗; 临床研究性
Keywords:
ARDS;  MaHuang FuZi XiXin decoction;  treatment;  clinical study
分类号:
R254.1
文献标志码:
B
摘要:
目的：观察麻黄附子细辛汤治疗急性呼吸窘迫综合征(ARDS)的疗效。方法：将ICU收治的ARDS 患者126例按随机数字表法分为治疗组和对照组各63例，2组患者均予控制原发病的治疗，治疗组在此基础上予麻黄附子细辛汤每日1～2剂口服或鼻饲。治疗3周对2组患者基本情况评分及应用抗生素时间，抗生素使用率，抗生素使用强度（DDDS）以及血管活性药物、肾上腺皮质激素应用时间，机械通气时间，ICU住院时间，死亡率等进行比较。结果：治疗后Marshall评分治疗组为（5.23±2.25）分，与对照组（6.10±1.42）分比较P＜0.05；APACHEⅡ评分治疗组为（10.36±4.78）分，与对照组(14.31±2.13)分比较P＜0.05；PaO2/FiO2治疗组为（342.00±56.34）mmHg，与对照组（296.00±42.63）mmHg比较（P＜0.05）；2组应用抗生素时间、抗生素使用率、DDDS、血管活性药物应用时间，机械通气时间、死亡率、ICU住院时间等比较差异具有统计学意义（P＜0.05）。结论：在治疗原发病基础上采用麻黄附子细辛汤治疗ARDS安全有效。
Abstract:
Objective: To investigate therapeutic effects of MaHuang FuZi XiXin decoction in treating acute respiratory distress syndrome (ARDS). Methods: All 126 patients admitted to ICU were allocated to the treatment group and the control group by random number table method, on the foundation of the treatment for primary disease, the treatment group received MaHuang FuZi XiXin decoction by mouth or nasal feeding. The scores of basic conditions of the patients in both groups, the time and the rate of using antibiotics, DDDS, the time of vasoactive agent, the time of adrenal cortex hormone, mechanical ventilation time, ICU hospitalization time, death rate and others were compared after treating for three weeks. Results: After treating, Marshall scores of the treatment group were (5.23±2.25), which were compared to (6.10±1.42) of the control group P＜0.05; APACHEⅡ scores of the treatment group were (10.36±4.78), they were compared with (14.31±2.13) of the control group P＜0.05; PaO2/FiO2 of the treatment group were (342.00±56.34) mmHg, higher than(296.00±42.63)mmHg of the control group P＜0.05; the difference showed statistical meaning in the time and the rate of using antibiotics, DDDS, the time of vasoactive agent, mechanical ventilation time, death rate, ICU hospitalization time and others (P＜0.05). Conclusion: MaHuang FuZi XiXin decoction is safe and effective in treating ARDS.

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[1]薛海霞,袁冰华,指导：李妍怡.肃肺清肠合剂对ARDS患者呼吸力学和血流动力学的影响[J].西部中医药,2013,26(06):62.
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[2]马春丽,于艺,迟倩慧,等.麻黄附子细辛汤治疗缓慢性心律失常的网络药理学机制[J].西部中医药,2024,37(02):104.[doi:10.12174/j.issn.2096-9600.2024.02.20]
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备注/Memo

备注/Memo:
收稿日期：2013-11-22作者简介：常荣天(1967—)，男，硕士学位，副主任医师，甘肃省重症医学委员会委员。研究方向：重症医学。
更新日期/Last Update: 2014-05-15