[1]闫雪华.恩替卡韦联合复方鳖甲软肝片治疗代偿期乙肝肝硬化疗效观察[J].西部中医药,2014,27(07):84-86.
　YAN Xuehua.Clinical Observation on Entecavir Combined with Compound BieJia RuanGan Tablets in Treating Decompensated Liver Cirrhosis of Hepatitis B[J].Western Journal of Traditional Chinese Medicine,2014,27(07):84-86.
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恩替卡韦联合复方鳖甲软肝片治疗代偿期乙肝肝硬化疗效观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年07期
页码:
84-86
栏目:
出版日期:
2014-07-15

文章信息/Info

Title:
Clinical Observation on Entecavir Combined with Compound BieJia RuanGan Tablets in Treating Decompensated Liver Cirrhosis of Hepatitis B
文章编号:
1004-6852(2014)07-0084-03
作者:
闫雪华
兰州市第二人民医院肝病科，甘肃 兰州 730046
Author(s):
YAN Xuehua
Department of Liver Disease of Lanzhou Municipality the Second People′s Hospital, Lanzhou 730046, China
关键词:
乙型肝炎; 肝硬化; 肝纤维化; 恩替卡韦片; 复方鳖甲软肝片
Keywords:
liver cirrhosis of hepatitis B;  liver fibrosis;  entecavir;  compound BieJia RuanGan tablets
分类号:
R575.2
摘要:
目的：观察恩替卡韦联合复方鳖甲软肝片治疗代偿期乙肝肝硬化临床疗效。方法：将56 例乙肝肝硬化代偿期患者随机分为恩替卡韦与复方鳖甲软肝片联合治疗组及恩替卡韦单药组，分别于治疗前和治疗后48周检测肝功能、HBV-DNA、血清肝纤维化指标及肝脏瞬时弹性成像测定。结果：2组患者治疗后肝功能好转、HBV-DNA水平下降，2组比较无明显差异（P＞0.05），但联合治疗组肝纤维化程度改善更明显（P＜0.05）。结论：恩替卡韦与复方鳖甲软肝片联合治疗在抗纤维化程度方面优于单用恩替卡韦。
Abstract:
Objective: To explore curative effects of entecavir and compound BieJia RuanGan tablets in treating decompensated liver cirrhosis of hepatitis B. Methods: All 56 patients were randomized into 29 cases of the treatment group and 27 cases of the control group, liver function, HBV-DNA, the indexes of liver fibrosis in the serum and liver fibroScan were detected before treating and in 48 weeks after treating. Results: After treating, liver functions were improved, the levels of HBV-DNA were decreased in both groups, there was no significant difference (P＞0.05); the improvements of liver fibrosis in the treatment group were more remarkable (P＜0.05). Conclusion: Curative effects of entecavir and compound BieJia RuanGan tablets are superior to the effects of entecavir in treating fibrosis.

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备注/Memo

备注/Memo:
收稿日期：2013-12-20作者简介：闫雪华(1973—)，女，硕士学位，副主任医师。研究方向：病毒性肝炎的防治。
更新日期/Last Update: 2014-07-15