[1]马青.中西药物联合治疗急性髓系白血病 48 例[J].西部中医药,2014,27(08):86-87.
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中西药物联合治疗急性髓系白血病 48 例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年08期
页码:
86-87
栏目:
出版日期:
2014-08-15

文章信息/Info

文章编号:
1004-6852(2014)08-0028-03
作者:
马青
临夏州人民医院血液科,甘肃 临夏 731100
关键词:
髓系白血病急性益气健脾补肾汤阿柔比星阿糖胞苷诱导缓解方案
分类号:
R733.71
摘要:
目的:观察益气健脾补肾汤联合阿柔比星、阿糖胞苷诱导缓解化疗方案治疗急性髓系白血病(AML)的临床疗效。方法:将96例患者随机分为对照组和观察组各48例,2组均给予阿柔比星联合阿糖胞苷诱导缓解化疗方案。观察组在此基础上给予益气健脾补肾汤,化疗期间,1剂/d,水煎分服。结果:完全缓解率观察组为50.0%,对照组为25.0%,2组比较差异显著(P<0.05)。总有效率观察组为79.2%,对照组为45.8%,2组比较差异显著(P<0.05)。出血、感染、胃肠道反应、骨髓抑制、肝功能异常等不良反应发生率观察组显著低于对照组(P<0.05)。6、12、18个月时复发率对照组为25.0%、54.2%、58.3%,观察组为16.7%、20.8%、20.8%。2组比较差异具有统计学意义(P<0.05)。结论:益气健脾补肾汤联合阿柔比星、阿糖胞苷诱导缓解化疗方案治疗AML疗效确切,复发率低,可以有效降低化疗毒性反应。

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备注/Memo

备注/Memo:
作者简介:马青(1969—),男, 副主任医师。研究方向:血液病的临床诊治。
更新日期/Last Update: 2014-08-15