[1]严亚锋,白海侠,周海哲,等.脑清通颗粒对高血压肝热痰瘀证大鼠血浆ET-1和Ang II含量的影响[J].西部中医药,2015,28(09):10-13.
点击复制

脑清通颗粒对高血压肝热痰瘀证大鼠血浆ET-1和Ang II含量的影响
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年09期
页码:
10-13
栏目:
出版日期:
2015-09-15

文章信息/Info

文章编号:
1004-6852(2015)09-0010-04
作者:
严亚锋1白海侠1周海哲1李香2
1 陕西中医药大学,陕西 咸阳 712046; 2山东省肥城市老城街道卫生院
关键词:
高血压肝热痰瘀证ET-1AngⅡ脑清通颗粒
分类号:
R331.3
文献标志码:
A
摘要:
目的:观察脑清通颗粒对高血压肝热痰瘀证大鼠血浆中内皮素-1(ET-1)和血管紧张素Ⅱ(AngⅡ)含量的影响,探讨其治疗高血压的作用机制。方法:采用慢性复合电刺激加高脂饮食致大鼠高血压肝热痰瘀证模型,测定大鼠血浆中ET-1和AngⅡ的含量。结果:与治疗前及模型组比较,脑清通颗粒各剂量组治疗第2周血压明显降低(P<0.01),第3周降压作用最明显;与模型组比较,脑清通颗粒各剂量组均能降低模型大鼠血浆中ET-1和AngⅡ的含量(P<0.01)。结论:脑清通颗粒可降低高血压肝热痰瘀证模型大鼠血压,其降压机制可能与降低血浆中ET-1和AngⅡ的含量有关。

相似文献/References:

[1]马学芳,郜志宏.老年高血压中医证型与危险因素之间的相关性研究[J].西部中医药,2012,25(10):79.
 MA Xue-fang,GAO Zhi-hong.Relevant Study between Senile Hypertension and Risk Factors of TCM Syndrome[J].Western Journal of Traditional Chinese Medicine,2012,25(09):79.
[2]王记,指导:李应东.李应东教授以补虚活血法论治高血压经验[J].西部中医药,2013,26(04):49.
 WANG Ji,DirectorLI Yingdong.Professor LI Y ingdong's Experience of Tonifying Deficiency and Activating Blood Method for Hypertension[J].Western Journal of Traditional Chinese Medicine,2013,26(09):49.
[3]徐宏.益水生新饮对高血压早期肾损害患者血液流变学及ALB和α1-MG的影响*[J].西部中医药,2013,26(06):4.
 XU Hong.Effects of Y iShui ShengXinY in on Hemorheology, ALB and α1-MG of Hypertensive Patients with Early Renal Damage[J].Western Journal of Traditional Chinese Medicine,2013,26(09):4.
[4]魏丽丽.45例妊娠高血压患者眼底检查分析[J].西部中医药,2012,25(08):112.
 WEI Li-li.Analysis on Eyeground Examination of 45 Pregnant Patients with Hypertension[J].Western Journal of Traditional Chinese Medicine,2012,25(09):112.
[5]刘希宏.中西药物联用对老年高血压合并2型糖尿病患者肾功能的保护作用[J].西部中医药,2012,25(07):9.
 LIU Xi-hong.Protection of Integrated Traditional Chinese and Western Medicine on Renal Function of Patients with Senile Hypertension and Type 2 Diabetes Mellitus[J].Western Journal of Traditional Chinese Medicine,2012,25(09):9.
[6]张成慰.天麻钩藤饮联合氯沙坦治疗肾性高血压60例[J].西部中医药,2013,26(09):76.
 ZHANG Chengwei.TianMa GouTeng Drink and Losartan for 60 Cases of Renal Hypertension[J].Western Journal of Traditional Chinese Medicine,2013,26(09):76.
[7]刘赵丽,徐耀,张昶,等.中药腿足浴疗法治疗Ⅰ级高血压疗效观察[J].西部中医药,2013,26(10):113.
 LIU Zhaoli,XU Yao,ZHANG Chang,et al.Observation on TCM Leg-feet Balneotherapy for Hypertension Level One[J].Western Journal of Traditional Chinese Medicine,2013,26(09):113.
[8]丁劲,施兴艳.中医护理干预对肝阳上亢型高血压睡眠障碍的影响*[J].西部中医药,2013,26(10):115.
 DING Jin,SHI Xingyan.Effects of TCM Nursing Intervention on Sleep Disorder Induced by Hypertension of Liver Yang Hyperactivity Pattern[J].Western Journal of Traditional Chinese Medicine,2013,26(09):115.
[9]蒋文潇,王保和△.从气虚角度探讨眩晕与高血压病机的相关性[J].西部中医药,2014,27(03):61.
 JIANG Wenxiao,WANG Baohe.A Probe into the Relationship between the Pathogenesis of Hypertension and Vertigo from the Angle of Qi Deficiency[J].Western Journal of Traditional Chinese Medicine,2014,27(09):61.
[10]郭海莉.某医院临床高血压患者的服药依从性调查分析[J].西部中医药,2014,27(09):69.

备注/Memo

备注/Memo:
*基金项目:陕西省教育厅2013年科学研究项目计划(自然科学专项)(编号2013JK0831);陕西省教育厅2014年科学研究项目计划(自然科学专项)(编号14JK1195)。作者简介:严亚锋(1976—),男,硕士学位,工程师,讲师。研究方向:老年病的防治及其中药药理学。
更新日期/Last Update: 2015-09-15