[1]柳春玲,周黎黎,牛亭惠,等.运脾颗粒对幼龄厌食模型大鼠消化功能的影响[J].西部中医药,2016,29(02):9-12.
　LIU Chunling,ZHOU Lili,NIU Tinghui,et al.Influence of YunPi Granules on Digestive Function of Juvenile Rats with Anorexia[J].Western Journal of Traditional Chinese Medicine,2016,29(02):9-12.
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运脾颗粒对幼龄厌食模型大鼠消化功能的影响()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
29
期数:
2016年02期
页码:
9-12
栏目:
出版日期:
2016-02-15

文章信息/Info

Title:
Influence of YunPi Granules on Digestive Function of Juvenile Rats with Anorexia
文章编号:
1004-6852(2016)02-0009-04
作者:
柳春玲1，周黎黎2，牛亭惠3，杜丽东3，4' target="_blank" rel="external">4，吴国泰3，4' target="_blank" rel="external">4
1 兰州市中医医院，甘肃 兰州 730050； 2 甘肃省中医院；3 甘肃中医药大学； 4 甘肃省中药药理与毒理学重点实验室
Author(s):
LIU Chunling1, ZHOU Lili2, NIU Tinghui3, DU Lidong3，4' target="_blank" rel="external">4, WU Guotai3，4' target="_blank" rel="external">4
1 Lanzhou Municipality TCM Hospital, Lanzhou 730050, China;2 Gansu Provincial Hospital of Traditional Chinese Medicine; 3 Gansu University of Traditional Chinese Medicine; 4 Key Laboratory of Pharmacology and Toxicology for Traditional Chinese Medicines of Gansu Province(nurturing station)
关键词:
运脾颗粒; 幼龄; 厌食模型大鼠; 消化功能
Keywords:
YunPi granules;  juvenile;  rats with anorexia;  digestive function
分类号:
R285.5
文献标志码:
A
摘要:
目的：探讨运脾颗粒对幼龄厌食模型大鼠消化功能的影响。方法：将60只SD幼龄大鼠随机分为正常对照组、模型对照组、阳性对照组(儿宝颗粒，1.75 g/kg)、运脾颗粒高剂量组( 4.20 g/kg)、运脾颗粒中剂量组(2.10 g/kg )、运脾颗粒低剂量组(1.05 g/kg )，每组10只，模型建立后灌胃给药。结果：与模型对照组比较，运脾颗粒不同剂量组体质量均有不同程度的增加(P＜0.05)；与模型对照组比较，运脾颗粒不同剂量组24小时摄食量均有不同程度的增加(P＜0.05)；与模型组对照组比较，运脾颗粒高剂量组大鼠胃排空率和肠推进率明显增大(P＜0.05)；与模型对照组比较，运脾颗粒各剂量组大鼠脾脏指数均明显减小(P＜0.05)。结论：运脾颗粒对幼龄厌食模型大鼠一定的调节作用。
Abstract:
Objective: To explore the influence of YunPi granules on digestive function of juvenile rats with anorexia. Methods: Sixty SD rats were randomized into normal control group, model control group, positive control group (ErBao granules, 1.75 g/kg), high (4.20 g/kg), moderate (2.10 g/kg) and low (1.05 g/kg) doses groups of YunPi granules, ten rats each group, the models accepted intragastric administration after the models were established. Results: Compared with model control group, body weights of rats in different doses groups of YunPi granules increased in different degrees(P＜0.05); compared with the model control group, 24hours food intake of the rats in different doses groups of YunPi granules increased to different extents(P＜0.05); compared with the model control group, gastric emptying rate and intestinal propulsion rate increased remarkably in high dose group of YunPi granules (P＜0.05); compared with the model control group, spleen indexes of the rats in different doses groups of YunPi granules decreased notably(P＜0.05). Conclusion: YunPi granules could regulate juvenile rats with anorexia to a certain degree.

相似文献/References:

[1]周黎黎,任耀全,柳春玲.运脾颗粒治疗脾虚型小儿厌食的临床观察[J].西部中医药,2015,28(03):110.
[2]周黎黎,柳春玲,沈玉鹏,等.运脾颗粒对幼龄厌食模型大鼠胃肠激素水平的影响[J].西部中医药,2017,30(03):12.
　ZHOU Lili,LIU Chunling,SHEN Yupeng,et al.Effect of YunPi Granule on Gastrointestinal Hormone Levels in Juvenile Anorexia Rat Models[J].Western Journal of Traditional Chinese Medicine,2017,30(02):12.
[3]马国珍,舒劲,王煜,等.运脾颗粒对功能性消化不良大鼠胃肠激素的影响[J].西部中医药,2018,31(04):20.
　MA Guozhen,SHU Jin,WANG Yu,et al.Effects of Spleen-activating Granules on Gastrointestinal Hormone of the Rats with Functional Dyspepsia[J].Western Journal of Traditional Chinese Medicine,2018,31(02):20.
[4]陈燕云,李初谊,李竞.运脾颗粒对功能性消化不良小鼠胃肠运动和胃泌素、抑胃肽的影响[J].西部中医药,2021,34(07):44.[doi:10.12174/j.issn.2096-9600.2021.07.10]
　CHEN Yanyun,LI Chuyi,LI Jing.Effects of Spleen-activating Granules on Gastrointestinal Motility, Gastrin, Gastric Inhibitory Polypeptide in the Mice with Functional Dyspepsia[J].Western Journal of Traditional Chinese Medicine,2021,34(02):44.[doi:10.12174/j.issn.2096-9600.2021.07.10]

备注/Memo

备注/Memo:
*基金项目：甘肃省中医药管理局科研立项课题（编号GZK-2014-28）。作者简介：柳春玲(1963—)，副主任医师。研究方向：内科及儿科常见疾病的诊治。
更新日期/Last Update: 2016-02-15