[1]吴燕,金芳梅.针灸联合甲氨喋呤治疗类风湿性关节炎53例[J].西部中医药,2016,29(02):126-128.
 WU Yan,JIN Fangmei.Treating 53 Cases of Rheumatoid Arthritis by Acupuncture and Methotrexate[J].Western Journal of Traditional Chinese Medicine,2016,29(02):126-128.
点击复制

针灸联合甲氨喋呤治疗类风湿性关节炎53例()
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
29
期数:
2016年02期
页码:
126-128
栏目:
出版日期:
2016-02-15

文章信息/Info

Title:
Treating 53 Cases of Rheumatoid Arthritis by Acupuncture and Methotrexate
文章编号:
1004-6852(2016)02-0126-03
作者:
吴燕金芳梅
甘肃省中医院,甘肃 兰州 730050
Author(s):
WU Yan, JIN Fangmei
Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
关节炎类风湿性针灸甲氨喋呤
Keywords:
arthritis rheumatoid acupuncture methotrexate
分类号:
R593.22
文献标志码:
B
摘要:
目的:观察针灸联合甲氨喋呤治疗类风湿性关节炎(rheumatoid arthritis,RA)的临床疗效。方法:将106例RA患者随机分为观察组、对照组各53例,观察组给予针灸联合甲氨喋呤治疗,对照组给予甲氨喋呤治疗。疗程均为4个月,观察2组临床症状、实验室指标和不良反应。结果:总有效率观察组为88.68%,对照组为71.70%,2组比较差异有统计学意义(P<0.05 )。疼痛程度评分、晨僵时间、双手握力、15 m步行时间、血沉(ESR)、C反应蛋白(CRP)、类风湿因子(RF)等指标2组治疗后均明显改善(P<0.05 ),观察组改善更明显(P<0.05 )。2组不良反应发生率差异无统计学意义(P>0.05 )。结论:针灸联合甲氨喋呤治疗RA有较好的临床疗效和安全性。
Abstract:
Objective: To observe curative effects of acupuncture jointed with methotrexate in the treatment for rheumatoid arthritis (RA). Methods: All 106 patients were divided into the observation group and the control group, 53 cases each group, the observation group accepted acupuncture and methotrexate, the control group methotrexate only. Both groups were treated for four months. Clinical symptoms, lab indexes and adverse reaction of both groups were observed. Results: Total effective rate of the observation group was 88.68%, higher than 71.70% of the control group, the difference had statistical meaning (P<0.05). Pain degree scales, morning stiffness time, hand grip, 15m walking time, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), rheumatoid factors (RF) and others improved significantly after treating in both groups (P<0.05), the improvement of the observation group was more obvious (P<0.05). There was no significant difference in the comparison of the incidence of adverse reaction between both groups (P>0.05). Conclusion: Acupuncture jointed with methotrexate in the treatment for rheumatoid arthritis (RA) show better clinical effects and safety.

相似文献/References:

[1]覃仕化,汪悦.痹痛灵颗粒对胶原诱导性关节炎大鼠血清及滑膜组织匀浆中IL-2的影响[J].西部中医药,2011,24(11):9.
[2]陈志龙,徐霞,申建军,等.中药洗剂外敷配合舒血宁注射液治疗膝关节骨性关节炎80例[J].西部中医药,2011,24(11):31.
[3]赵军,邢涛,董林,等.骨刺消巴布剂对兔膝骨性关节炎IL-1β和TNF-α的影响*[J].西部中医药,2012,25(11):25.
 ZHAO Jun,XING Tao,DONG Lin,et al.Effects of GuCiXiao Cataplasm on IL-1β and TNF-α of Rabbits with Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(02):25.
[4]雷斌,宋敏△,刘宗权.阶梯疗法在膝骨性关节炎治疗中的指导意义[J].西部中医药,2012,25(11):116.
 LEI Bin,SONG Min,LIU Zong-quan.Guiding Significance of Rescue by Stages in the Treatment of Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(02):116.
[5]姚兴璋,李兴勇△.从流行病学浅析膝关节骨性关节炎的危险因素[J].西部中医药,2012,25(09):132.
 YAO Xing-zhang,LI Xing-yong.Analysis of Epidemiology on Risk Factors of Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(02):132.
[6]张勇.四妙永安汤加味治疗急性痛风性关节炎140例[J].西部中医药,2012,25(07):59.
 ZHANG Yong.Clinical Observation on Modified SiMiao YongAnTang in Treating 140 Cases of Acute Gouty Arthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(02):59.
[7]侯建平,王亚军,严亚峰,等.虎杖提取物抗动物高尿酸血症的实验研究[J].西部中医药,2012,25(05):21.
 HOU Jian-ping,WANG Ya-jun,YAN Ya-feng,et al.Study of Polygonum Cuspidatum Extract on Anti-Hyperuricemia in Rats and Mice[J].Western Journal of Traditional Chinese Medicine,2012,25(02):21.
[8]董三明.针刺配合中药熏洗治疗退行性膝关节炎30例[J].西部中医药,2013,26(09):106.
 DONG Sanming.Needling and TCM Fumigation in Treating 30 Cases of Degenerative Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2013,26(02):106.
[9]李凡.针灸治疗膝关节骨性关节炎30例[J].西部中医药,2013,26(09):108.
 LI Fan.Treatment for 30 Cases of Knee Osteoarthritis with Acupuncture[J].Western Journal of Traditional Chinese Medicine,2013,26(02):108.
[10]赵颖林,李延红,张满臣,等.活络止痛软膏配合手法和功能锻炼治疗膝骨性关节炎90例*[J].西部中医药,2013,26(10):106.
 ZHAO Yinglin,LI Yanhong,ZHANG Manchen,et al.HuoLuo ZhiTong Ointment, Manipulation and Functional Exercise in Treating 90 Cases of Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2013,26(02):106.
[11]唐瑛,肖力强,江花,等.中药复方敷擦外治类风湿性关节炎的用药规律研究*[J].西部中医药,2013,26(05):57.
 TANG Ying,XIAO Liqiang,JIANG Hua,et al.Research on the Law of Medicine Application of TCM Compound in Treating Rheumatoid Arthritis for External Use[J].Western Journal of Traditional Chinese Medicine,2013,26(02):57.
[12]张振顺.宣痹汤合二妙散加减治疗类风湿性关节炎的临床观察[J].西部中医药,2012,25(08):77.
 ZHANG Zhen-shun.Clinical Observation on Modified XuanBiTang and ErMiaoSan in Treating Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(02):77.
[13]胡学玲.中药塌渍配合红外线治疗类风湿性关节炎临床观察[J].西部中医药,2012,25(07):96.
 HU Xue-ling.Clinical Observation on Hot Compress with Herbs and Infrared in Treating Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(02):96.
[14]曹江山,庄贺,侯王君,等.独活寄生汤治疗活动期类风湿性关节炎29例[J].西部中医药,2014,27(02):102.
 CAO Jiangshan,ZHUANG He,HOU Wangjun,et al.Treatment for 29 Patients with Rheumatoid Arthritis at Active Stage by DuHuo JiSheng Tang[J].Western Journal of Traditional Chinese Medicine,2014,27(02):102.
[15]刘国强.三痹汤加减联合甲氨喋呤治疗类风湿性关节炎48例疗效观察[J].西部中医药,2014,27(03):107.
 LIU Guoqiang.Observation on Modified SanBi Tang and Methotrexate in Treating 48 Cases of Rheumatoid arthritis[J].Western Journal of Traditional Chinese Medicine,2014,27(02):107.
[16]倪角角,金芳梅.蜡疗配合护理干预治疗类风湿性关节炎35例[J].西部中医药,2016,29(04):124.
 NI Jiaojiao,JIN Fangmei.Wax Therapy Combined with Nursing Intervention in Treating 35 Patients with Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2016,29(02):124.
[17]马风英.仙灵骨葆胶囊联合甲氨蝶呤治疗类风湿性关节炎继发骨质疏松症37例[J].西部中医药,2018,31(02):98.
 MA Fengying.XianLing GuBao Capsules Combined with Methotrexate in Treating 37 Rheumatiod Arthritis Patients with Secondary Osteoporosis[J].Western Journal of Traditional Chinese Medicine,2018,31(02):98.
[18]刘继业,李丰林.益肾祛痹汤联合西药治疗类风湿性关节炎60例[J].西部中医药,2018,31(06):93.
 LIU Jiye,LI Fenglin.Kidney-tonifying Arthralgia-eliminating Decoction Combined with Western Medicine in Treating 60 Cases of Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2018,31(02):93.
[19]高雪军,刘佳,李小姣,等.中药熏蒸联合温针灸治疗类风湿性关节炎29例[J].西部中医药,2018,31(06):111.
 GAO Xuejun,LIU Jia,LI Xiaojiao,et al.Herbal Fumigation Combined with Warm Needling Method in Treating 29 Cases of Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2018,31(02):111.
[20]许松梅.心理护理对类风湿性关节炎患者心理状态及生活质量的影响[J].西部中医药,2018,31(10):144.
 XU Songmei.Influence of Psychological Nursing on Psychological State and Quality of Life of RA Patients[J].Western Journal of Traditional Chinese Medicine,2018,31(02):144.

备注/Memo

备注/Memo:
作者简介:吴燕(1975—),女,主治医师。研究方向:风湿病的临床诊治。
更新日期/Last Update: 2016-02-15