接骨丹对大鼠胫骨骨折愈合疗效的影像学研究-《西部中医药》

文章信息/Info

Title:: Imaging Study on Curative Effects of JieGu Pills in Healing the Rats with Bone Defect

作者:: 牛恒立1，赵国彪2，马中兴3，陈晓东4△，白雪红5; 1 兰州大学第二医院，甘肃兰州 730030； 2 兰州大学药学院； 3 秦安县人民医院； 4 甘肃药业信息研究所； 5 甘肃省人民医院

Author(s):: NIU Hengli1, ZHAO Guobiao2, MA Zhongxing3, CHEN Xiaodong4△, BAI Xuehong5; 1 Lanzhou University Second Hospital, Lanzhou 730030, China;2 Pharmacy School of Lanzhou University； 3 Qin′an County People′s Hospital;4 Gansu Institute for Pharmaceutical Information; 5 Gansu Provincial Hospital

摘要:: 目的：探讨接骨丹对骨缺损愈合及骨形成的影响。方法：采用开放性骨折模型制作方法制作大鼠骨缺损模型，通过拍摄胫骨X光片，并根据骨折肢X片评分标准，对各组大鼠不同时间段骨折肢进行相应评分，考察接骨丹对骨折愈合及骨形成的影响。结果：给药组较空白组骨缺损部位骨痂生成良好、骨缺损明显减小、骨折肢X线片评分明显高于空白对照组(P＜0.05)。结论：接骨丹对骨缺损愈合及骨形成有促进作用。

Abstract:: Objective: To explore the influence of JieGu pills on the healing of bone defect and bone formation. Methods: Rat model with bone defect was prepared by adopting open bone fracture model establishment method, the fracture limb of the rats in different groups were scored at different times by filming tibial X-ray according to fractured limb X-ray scaling standard, and the influence of JieGu pills on the healing of bone fracture and bone formation was discussed. Results: Callus formation grew well, and bone defects reduced obviously when the medication group was compared with the blank group, it was higher than blank control group in X-ray scales of fractured limbs obviously (P＜0.05). Conclusion: JieGu pills could promote the healing of bone defect and bone formation.