[1]刘鹏,肖勇,江立富,等.气管炎颗粒一定质量比配伍治疗慢性支气管炎疗效比较[J].西部中医药,2017,30(03):9-12.
 LIU Peng,XIAO Yong,JIANG Lifu,et al.Effects Comparison of Tracheitis Granules in Certain Mass Ratio Drugs Compatibility in the Treatment of Chronic Bronchitis[J].Western Journal of Traditional Chinese Medicine,2017,30(03):9-12.
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气管炎颗粒一定质量比配伍治疗慢性支气管炎疗效比较()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年03期
页码:
9-12
栏目:
方药·方剂配伍
出版日期:
2017-03-15

文章信息/Info

Title:
Effects Comparison of Tracheitis Granules in Certain Mass Ratio Drugs Compatibility in the Treatment of Chronic Bronchitis
文章编号:
1004-6852(2017)03-0009-04
作者:
刘鹏肖勇江立富李伟 邢琦潘宇杰
解放军第五医院,宁夏 银川 750004
Author(s):
LIU Peng XIAO Yong JIANG Lifu LI Wei XING Qi PAN Yujie
The Fifth Hospital of PLA, Yinchuan 750004, China
关键词:
慢性支气管炎气管炎颗粒药材质量比配伍治疗临床研究性
Keywords:
chronic bronchitis tracheitis granules medicinal material quality ratio treatment clinical study
分类号:
R256.1
文献标志码:
A
摘要:
目的:探讨气管炎颗粒药材一定质量比配伍治疗慢性支气管炎的临床及中医证型疗效。方法:提取不同质量比配伍的药材[甘草∶黄芪∶白术(2∶2∶1),苦杏仁:旋覆花:百部:桔梗(1∶3∶3.5∶2.2)]有效活性成分,制成颗粒。将慢性支气管炎患者490例随机分为2组。治疗组冲服气管炎颗粒10 g/次,3次/d。对照组口服与气管炎颗粒处方相同药味和剂量的汤剂,100 mL/ 次,3次/d。2组同时均进行心理辅导和健康指导。比较2组患者临床疗效、中医证型疗效及血清白细胞介素6(IL-6)、肿瘤坏死因子α(TNF-α)含量。结果:临床总有效率2组比较差异有统计学意义(P<0.05);中医证型疗效方面热蕴肺证、痰浊阻肺证、肺肾气虚证、风寒袭肺证患者2组比较差异有统计学意义(P<0.05);血清IL-6、TNF-α 2组比较差异有统计学意义(P<0.05)。结论:气管炎颗粒药材一定质量比配伍治疗慢性支气管炎有较好的临床及中医证型疗效。
Abstract:
Objective: To study the clinical effects and TCM syndromes effects of certain mass ratio drugs compatibility of bronchitis granules in the treatment of chronic bronchitis. Methods: Active ingredients were extracted from GanCao (Glycyrrhiza uralensis Fisch.), HuangQi (Radix Astragalus), and BaiZhu (Atractylodes macrocephala) (medicinal material quality ratio of them was 2∶2∶1) and KuXingRen (Semen Armeniacae Amarum), inula flower, BaiBu (radix stemonae) and JieGeng (Platycodon grandiflorum) (medicinal material quality ratio of them was 1∶3∶3.5∶2.2) for making granules. All 490 patients with chronic bronchitis were randomly divided into two groups. The treatment group was treated by tracheitis granules after mixing it with water, 10 g/time, three times /d. The control group was treated by orally taking the decoction with the same herbs and dose in the tracheitis granules, 100 mL/time, three times/d. And both groups were given psychological services and health guidance. Clinical effects, TCM syndromes effects, the contents of serum IL-6 and TNF-αof patients in two groups were compared. Results: In the aspect of clinical total effective rates, the differences between two groups were statistically significant (P<0.05). In the aspect of TCM syndromes effect, there were statistically significant differences among patients with heat stagnated in lung syndrome, phlegm stagnated in lung syndrome, lung and kidney Qi deficiency syndrome and wind-cold attacking lung syndrome between two groups(P<0.05). Compared the serum IL-6 and TNF-α levels between two groups, the differences were statistically significant (P<0.05). Conclusion: Certain mass ratio drugs compatibility of tracheitis granules in the treatment of chronic bronchitis has good clinical effects and TCM syndromes effects.

相似文献/References:

[1]王 洋,韩玲爱,王永兴,等.黄龙咳喘胶囊治疗慢性支气管炎急性发作期(肺肾气虚、痰热郁肺证)的有效性和安全性[J].西部中医药,2015,28(11):6.

备注/Memo

备注/Memo:
收稿日期:2015-08-06 作者简介:刘鹏(1978—),男,主管药师。研究方向:医院药学。
更新日期/Last Update: 2017-03-15