[1]丁高恒,殷晓春,慕婷婷,等.敦煌遗方“神仙粥”抗衰老作用的研究[J].西部中医药,2018,31(02):19-21.
　DING Gaoheng,YIN Xiaochun,MU Tingting,et al.Study on Anti-aging Effects of “ShenXian Zhou” in DunHuang YiFang[J].Western Journal of Traditional Chinese Medicine,2018,31(02):19-21.
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敦煌遗方“神仙粥”抗衰老作用的研究()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年02期
页码:
19-21
栏目:
出版日期:
2018-02-15

文章信息/Info

Title:
Study on Anti-aging Effects of “ShenXian Zhou” in DunHuang YiFang
文章编号:
1004-6852(2018)02-0019-03
作者:
丁高恒，殷晓春，慕婷婷，孟军亮，裴凌云，刘永琦，蔺光遥，吴建军△
甘肃中医药大学，甘肃 兰州 730000
Author(s):
DING Gaoheng, YIN Xiaochun， MU Tingting， MENG Junliang，PEI Lingyun， LIU Yongqi， LIN Guangyao，WU Jianjun△
Gansu University of Chinese Medicine, Lanzhou 730000, China
关键词:
神仙粥; 敦煌遗方; 抗衰老; 动物实验; 大鼠
Keywords:
ShenXian Zhou;  DunHuang YiFang.;  anti-aging effect;  animal experiment;  the rats
分类号:
R2-09
文献标志码:
A
摘要:
甘肃中医药大学，甘肃 兰州 730000
Abstract:
Objective: To discuss the anti-aging effects and the mechanism of “ShenXian Zhou” in DunHuang YiFang. Methods: All 48 SPF healthy SD rats, aging two months and body weight (150±30)g,were selected, eight rats were randomly chosen and taken as the blank group, the other rats were prepared to the aging models through hypodermic injection of D-galactose (125 mg/(kg·d), the blank group were injected with equivalent dose of 0.9% physiological saline. After successfully preparing the models, the aging rat models were randomized into the model group, positive control group, low, moderate and high dose groups of ShenXian Zhou, eight rats each group, half male and half female, to perform the intervention experiment, basic conditions of the rats were observed simultaneously, organic level (thymus index, spleen index) and immunity levels (SOD and MDA) were observed to study anti-aging effects of ShenXian Zhou. Results: The difference had statistical meaning when organic levels and immunity levels of the model group were compared with the levels of the other five groups (P＜0.05). The difference had no statistical meaning in the comparisons among the other groups except the model group (P＞0.05), the difference was statistically significant when SOD activity and MDA contents of the model group were compared with these of the blank group, positive control group, high dose group of ShenXian Zhou(P＜0.05), the difference had no statistical meaning in the comparisons of the other groups except the model group (P＞0.05). Conclusion: “ShenXian Zhou” in DunHuang YiFang shows anti-aging effects.

相似文献/References:

[1]吴建军,丁高恒,殷晓春,等.敦煌遗方“神仙粥”对AD模型大鼠学习记忆能力及海马组织Bcl-2、Bax基因表达的影响[J].西部中医药,2019,32(04):19.
　WU Jianjun,DING Gaoheng,YIN Xiaochun,et al.Effects of DunHuang YiFang "ShenXian Zhou" on Learning and Memory Ability, the Expressions of Bcl-2 and Bax Gene in the Hippocampus of AD Rat Model[J].Western Journal of Traditional Chinese Medicine,2019,32(02):19.

备注/Memo

备注/Memo:
收稿日期：2017-06-20 *基金项目：敦煌医学与转化省部共建教育部重点实验室项目(编号DHYX14-005)。 作者简介：丁高恒(1991—)，男，在读硕士研究生。研究方向：公共卫生。 △通迅作者：吴建军(1972—)，男，医学博士，副教授，硕士研究生导师。研究方向：公共卫生。
更新日期/Last Update: 2018-02-15