[1]程晨,王燕萍,白瑞斌,等.复方红芪促睡眠颗粒剂制备工艺研究[J].西部中医药,2018,31(04):45-49.
　CHENG Chen,WANG Yanping,BAI Ruibin,et al.Research on the Preparation Process of Compound HongQi Boosting-sleep Granules[J].Western Journal of Traditional Chinese Medicine,2018,31(04):45-49.
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复方红芪促睡眠颗粒剂制备工艺研究()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年04期
页码:
45-49
栏目:
出版日期:
2018-04-15

文章信息/Info

Title:
Research on the Preparation Process of Compound HongQi Boosting-sleep Granules
文章编号:
1004-6852(2018)04-0045-05
作者:
程晨1，2，王燕萍2，白瑞斌2，张静2，杨扶德1，胡芳弟1，2△
1 甘肃中医药大学药学院，甘肃 兰州 730000； 2兰州大学药学院
Author(s):
CHENG Chen1,2, WANG Yanping2, BAI Ruibin2, ZHANG Jing2, YANG Fude1, HU Fangdi1，2△
1 School of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, China; 2 School of Pharmacy, Lanzhou University
关键词:
复方红芪方; 制备工艺; 浸膏粉; 正交实验
Keywords:
compound HongQi prescription;  the preparation technology;  powdered extract;  orthogonal test
分类号:
R283
文献标志码:
A
摘要:
目的：确定复方红芪促睡眠颗粒剂的制备工艺。方法：以正交实验法优选复方红芪促睡眠颗粒剂的最佳提取工艺条件，以最佳提取工艺条件进行制剂工艺研究。结果：取处方量的复方红芪方中药，加10倍水煎煮3次，l.5 h/次，合并煎液，静置，滤过，煎煮浓缩至相对密度为1.25～1.30(60℃)的稠膏，减压干燥(70℃)，得到干膏粉。干膏粉和糊精按1∶1.5混合均匀后以85%乙醇溶液为湿润剂制成颗粒，干燥，即得。结论：该制备方法简单可行，所得制剂质量稳定，可作为复方红芪促睡眠颗粒剂的制备工艺。
Abstract:
Objective: To confirm the preparation process of compound HongQi (manyinflorescenced sweet-vetch root) boosting-sleep granules. Methods: The best extraction conditions of compound HongQi boosting-sleep granules were optimized by orthogonal test, and the preparation technology was studied under the best extraction technology conditions. Results: The herbs were measured and selected according to compound HongQi prescription, after adding ten times water, the herbs were decocted for three times, 1.5 hours each time, decoction was merged, left to stand, filtrated, decocted to the thick paste in the relative density of 1.25~1.30(60℃), decompressed and dryied (70℃), to obtain dry paste powder. Dry paste powder and dextrine were mixed well in the ratio of 1: 1.5, and 85% ethanol solution was taken as the wetting agent to granulate and dry. Conclusion: The preparation method, simple and feasible with stable preparations, could be used to produce compound HongQi boosting-sleep granules.

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备注/Memo

备注/Memo:
收稿日期：2017-10-25 *基金项目：甘肃省科技计划项目（编号17ZC1LA016）；甘肃省科技重大专项（编号17ZD2FA009）；兰州市科技局专利转化项目（编号2017-4-119）。 作者简介：程晨(1989—)，女，在读硕士研究生。研究方向：中药学。 △通讯作者：胡芳弟(1971—)，女，博士学位，教授，博士研究生导师。研究方向：中药新药研发及中药质量标准研究。
更新日期/Last Update: 2018-04-15