[1]贾丽娜,康学智,李亚明,等.良性甲状腺结节患者血清维生素水平与中医辨证分型的相关性[J].西部中医药,2018,31(09):93-96.
　JIA Lina,KANG Xuezhi,LI Yaming,et al.The Correlation between TCM Syndrome Differentiation and Patterns and the Level of Vitamin of the Patients with Benign Thyroid Nodule[J].Western Journal of Traditional Chinese Medicine,2018,31(09):93-96.
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良性甲状腺结节患者血清维生素水平与中医辨证分型的相关性()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年09期
页码:
93-96
栏目:
出版日期:
2018-09-15

文章信息/Info

Title:
The Correlation between TCM Syndrome Differentiation and Patterns and the Level of Vitamin of the Patients with Benign Thyroid Nodule
文章编号:
1004-6852(2018)09-0093-04
作者:
贾丽娜1，康学智2，李亚明1，张 栩1△
1 复旦大学附属华东医院中医科，上海 200040； 2 上海交通大学附属第六人民医院针推伤科
Author(s):
JIA Lina1, KANG Xuezhi 2, LI Yaming1, ZHANG Xu1△
1 TCM Department, Huadong Hospital Affiliated to FuDan University, Shanghai 200040, China; 2 Traumatic Department of Acupuncture and Massage, the 6th People′s Hospital Affiliated to Shanghai Jiaotong University
关键词:
甲状腺结节; 维生素B6; 维生素B9; 肝郁气滞证; 肾气虚证; 肾阴虚证
Keywords:
thyroid nodule;  vitamin B6;  vitamin B9;  liver depression and Qi stagnation pattern;  renal Qi deficiency pattern;  renal Yin deficiency pattern
分类号:
R322
文献标志码:
B
摘要:
目的：探讨体内维生素水平与良性阶段甲状腺结节的相关性，以及不同中医证型患者维生素水平的差异性。方法：通过超声检查将疑似良性甲状腺结节患者84例分为正常甲状腺的对照组21例及良性甲状腺结节患者的病例组63例，采用中医辨证方法将病例组分为肝郁气滞证35例、肾气虚证14例、肾阴虚证14例；比较各组血清维生素A(VitA)，维生素D(VitD)，维生素E(VitE)，维生素B1(VitB1)，维生素B2(VitB2)，维生素B6(VitB6)，维生素B9(VitB9)，维生素C(VitC)水平的差异。结果：VitA、VitD、VitE、VitB1、VitB2、VitC水平各组间比较差异无统计学意义(P＞0.05)，VitB6水平病例组低于对照组(P＜0.05)。肝郁气滞证患者VitB6水平低于对照组(P＜0.01)，VitB9水平低于肾气虚证与肾阴虚证患者(P＜0.05)。结论：低VitB6水平与良性甲状腺结节有关，低VitB6水平成为肝郁气滞证区别于其他证型的特征，可为肝郁气滞证的辨病基础。低VitB9水平与肝郁气滞证相关。低VitB6和VitB9水平可为良性甲状腺结节中医辨病与辨证用药提供依据。
Abstract:
Objective: To discuss the correlation between the level of vitamin and benign thyroid nodule, and the difference of the levels of vitamin of the patients with different TCM patterns. Methods: All 84 patients who were proved with benign thyroid nodule by ultrasonic examination were separated into 21 cases of the control group (normal thyroid) and 63 cases of the medical cases group(benign thyroid nodule), medical cases group was divided into 35 cases of liver depression and Qi stagnation pattern, 14 cases of renal Qi deficiency pattern and 14 cases of renal Yin deficiency pattern; to compare the levels of vitamin A (VitA), vitamin D (VitD), vitamin E (VitE), vitamin B1 (VitB1), vitamin B2 (VitB2), vitamin B6 (VitB6),vitamin B9 (VitB9),vitamin C(VitC) in different groups. Results: There was no statistical difference in the comparisons of the levels of VitA, VitD, VitE, VitB1, VitB2 and VitC among the groups(P＞0.05), medical cases group was lower than the control group in the level of VitB6 (P＜0.05), the patients of liver depression and Qi stagnation pattern were lower than the control group in the level of VitB6 (P＜0.01), lower than the patients of renal Qi deficiency pattern and renal Yin deficiency pattern in the level of VitB9 (P＜0.05). Conclusion: Low level of VitB6 is related to benign thyroid nodule, low level of VitB6become the feature that distinguished liver depression and Qi stagnation pattern from other patterns, which could be taken as the basis of syndrome differentiation of liver depression and Qi stagnation pattern. Low level of VitB9 is connected to liver depression and Qi stagnation pattern. Low level of VitB6and VitB9could provide the reference for disease differentiation, syndrome differentiation and pharmacy of benign thyroid nodule.

备注/Memo

备注/Memo:
收稿日期：2017-06-02 *基金项目：国家自然科学基金项目(编号81001569， 81102657)。 作者简介：贾丽娜(1980—)，女，硕士学位，主治医师。研究方向：内分泌代谢疾病的中西医结合治疗。 △通讯作者：张栩(1960—)，男，硕士学位，主任医师。研究方向：免疫系统疾病的中西医结合治疗。
更新日期/Last Update: 2018-09-15