[1]郭敏,展锐,王红丽△.射干扶正口服液指纹图谱研究[J].西部中医药,2019,32(02):41-43.
 GUO Min,ZHAN Rui,WANG Hongli.Study on Fingerprint of SheGan FuZheng Oral Liquid[J].Western Journal of Traditional Chinese Medicine,2019,32(02):41-43.
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射干扶正口服液指纹图谱研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年02期
页码:
41-43
栏目:
方药·质量分析
出版日期:
2019-02-15

文章信息/Info

Title:
Study on Fingerprint of SheGan FuZheng Oral Liquid
文章编号:
1004-6852(2019)02-0041-03
作者:
郭敏展锐王红丽△
甘肃省中医院,甘肃 兰州 730050
Author(s):
GUO Min ZHAN Rui WANG Hongli△
Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
射干扶正口服液指纹图谱高效液相色谱法
Keywords:
SheGan FuZheng oral liquid fingerprint HPLC
分类号:
R282
摘要:
目的:建立射干扶正口服液的指纹图谱。方法:采用高效液相色谱法,色谱柱为Eclipse Plus C18柱(250 mm×4.6 mm,5 μm);流动相为乙腈-1%甲酸水溶液梯度洗脱;流速:1 mL/min;检测波长:242 nm;柱温:30℃;进样量:20 μL。采用中药指纹图谱相似度评价系统对10批射干扶正口服液指纹图谱进行评价。结果:标定了20个共有峰,其中4个共有峰分别为车前子苷、射干苷、黄芪甲苷、大黄素。10批射干扶正口服液指纹图谱相似度均大于0.971。结论:该法稳定、快速、简便,结果准确、可靠,可用于射干扶正口服液的质量控制。
Abstract:
Objective:To build the fingerprint of SheGan FuZheng oral liquid. Methods: Using HPLC method, chromatographic column was Eclipse Plus C18 column (250 mm×4.6 mm, 5 μm); mobile phase was acetonitrile-1% formic acid aqueous solution as gradient elution; flow rate: 1mL/min; detection wavelength: 242 nm; column temperature: 30℃; sample size: 20 μL. Fingerprints of ten batches of SheGan FuZheng oral liquids were evaluated using similarity evaluation system for herbal fingerprint. Results: All 20 common peaks were marked, among them, four common peaks were plantaridin, belamcandin, astragaloside A and emodin respectively. Fingerprint similarity of ten batches of SheGan FuZheng oral liquids were greater than 0.971. Conclusion: The method, stable, rapid, simple and convenient, accurate and reliable results, could used for quality control of SheGan FuZheng oral liquid.

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备注/Memo

备注/Memo:
收稿日期:2018-07-06 *基金项目:甘肃省中医药管理局项目(编号GZK-2014-65)。 作者简介:郭敏(1983—),女,硕士学位,主管药师。研究方向:中藏药质量标准化及活性成分筛选。 △通讯作者:王红丽(1978—),女,硕士学位,副主任药师。研究方向:天然产物及临床药学研究。
更新日期/Last Update: 2019-02-15